Clinical trials: Aged Skin
Breast Cancer
Capecitabine and Vinorelbine in Treating Older Women Who Have Metastatic Breast Cancer With or Without Bone Involvement
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003902
- Testing
- capecitabine, vinorelbine tartrate
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Swiss Cancer Institute
Breast Cancer, Estrogen Receptor Positive Breast Cancer
A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older
The purpose of this research study is to evaluate a decision aid to help women aged 70 and older decide on treatment for their breast cancer.
- Conditions
- Breast Cancer, Estrogen Receptor Positive Breast Cancer, Node-negative Breast Cancer, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
- Trial name
- NCT02823262
- Testing
- Breast Cancer Treatment Decision Aid for women 70+, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy Female Volunteer
Relationship Between Skin Microbiome, Epigenetic Age, and Facial Features in Aging
The goal of this observational study is to evaluate the effect of age on skin microbiome.
- Trial name
- NCT07431203
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
Breast Neoplasms
Australian Screening Mammography Decision Aid Trial (ASMDAT)
The purpose of the study is to develop and evaluate a decision aid to assist women aged 70 years and over to make an informed choice about whether to continue screening mammography.
- Trial name
- NCT00247442
- Testing
- Decision aid
- Where
- Australia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Wrinkle, Fatigue
Anti-ageing Efficacy of a Cosmetic Formulation Containing NMN (2%) Versus Placebo
The study aims at evaluating skin wrinkling, puffiness and fatigue and dark circle appearance on asian and african-american healthy volunteer cohorts receiving a cosmetic formulation containing NMN (2%).
- Conditions
- Wrinkle, Fatigue, Puffiness Around the Eyes
- Trial name
- NCT04685096
- Testing
- Test product creme, Reference creme
- Where
- 2 sites in United States, China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Seneque SA
Pressure Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Prevention of Pressure Injury (PI) in Hospitalised Infants, Children, and Young People (CYP) (Aged 0-19 Years)
What is the problem? Children and young people admitted to hospital can sometimes be harmed by what is called a pressure injury. Pressure injuries are sores (ulcers) that happen on areas of the skin that are under pressure.
- Trial name
- CYPPI (NCT07303569)
- Where
- United Kingdom
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Herpes Simplex
Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old
Main goal of this study is to compare the occurrence of serious adverse events (SAEs) between the herpes simplex (gD2-AS04) vaccine group and the Saline control group throughout the study period (up to month 12).
- Trial name
- NCT00224484
- Testing
- GSK208141, Havrix (investigational formulation)
- Where
- 151 sites in United States, Australia and 16 more
- Volunteers
- 5,960 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Women of Reproductive Age
The Effect Of Self-Breast Examination Training On The Belief Of Breast Health
The aim of the present research was to detect the effect of self-breast examination provided to women between 18 and 49 years of age and practice on the belief of women on their breast health.
- Trial name
- NCT06410573
- Testing
- Breast Self-Examination and Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Hair Thinning, Hair Loss
A Clinical Trial to Examine the Efficacy of a Supplement to Support Healthy Hair and Skin
This is a triple-blinded, randomized, placebo-controlled clinical trial designed to evaluate the efficacy of Scale Media's Live Conscious Beyond Collagen supplement on overall hair and skin health.
- Trial name
- NCT06579742
- Testing
- Live Conscious Beyond Collagen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Scale Media Inc
Skin Aging
Effectiveness of a Bilayering Serum and Cream Containing GABA, DMAE, Cysteamine, and Bakuchiol for Skin Whitening and Anti-Aging
This study aims to evaluate the clinical efficacy and safety of a multi-functional bilayering skincare regimen-consisting of a serum and cream-for improving skin brightness and reducing wrinkles.
- Trial name
- NCT07477288
- Testing
- GABA, DMAE, Cysteamine
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Renal Transplant
Kidney Transplant Low-AGE Diet Study
The purpose of the present study is to test the feasibility of conducting a larger randomised controlled trial (RCT) which will investigate whether a diet low in toxins called advanced glycation end-products (AGEs) decreases skin…
- Trial name
- Transplant LAD (NCT05104242)
- Testing
- Diet low in Advanced Glycation End-Products (AGE)
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Fever
Development of a Fever Detection Algorithm Based on Non-invasive Skin-based Sensor Values in Infants up to 18 Months of Age
Fever of infants up to 18 months of age will be monitored in the hospital using the standard clinical methods and wearable research prototypes.
- Trial name
- NCT04654559
- Testing
- Unobtrusive data collection using wearable non-invasive sensors
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- greenTEG AG
Breast Cancer, Hormone Receptor Positive, Aromatase Inhibitor-Associated Arthralgia
Geriatric Oncology Assessment and Coping Skills Training for Older Women on Aromatase Inhibitor Therapy
Older women (≥65 years) with HR+ non-metastatic breast cancer experience high symptom burden and reduced quality of life during aromatase inhibitor (AI) therapy.
- Trial name
- GOAL-AI (NCT07232056)
- Testing
- GOAL-AI, CST-AI
- Volunteers
- 452 people
- Sponsor
- Duke University
Atopic Dermatitis
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)
The primary objective of the study is to assess the long-term safety of dupilumab in pediatric participants with AD. The secondary objectives of the study are: To assess the long-term efficacy of dupilumab in pediatric…
- Trial name
- NCT02612454
- Testing
- Dupilumab
- Where
- 84 sites in United States, Canada and 5 more
- Volunteers
- 880 people
- Sponsor
- Regeneron Pharmaceuticals
Skin Aging
Comparison of Outcome Parameters in Laser Rhytide Treatment
We previously published a comparative split-face study which has shown a significant, albeit moderate, effect of ablative fractional laser treatment.
- Trial name
- NCT00994474
- Testing
- Fractional carbon dioxide laser treatment, Fractional Er:YAG laser treatment
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Laserklinik Karlsruhe
Skin Manifestations
New Regenerative Approach for Dermal Renovation (Karisma)
Purpose/Objectives of the Study: Regenerative medicine, as well as aesthetic plastic surgery and dermatology field persistently seeks innovative, minimally invasive interventions to enhance skin quality and mitigate signs of…
- Trial name
- Karisma (NCT06152718)
- Testing
- Karisma
- Where
- 2 sites in Italy, Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Photo-aged Skin
Efficacy and Safety Evaluation of Microfocused Ultrasound Combined With 1550 nm Non-Ablative Fractional Laser for Facial Rejuvenation
This study adopted the research method of a single-center case-control study. According to the inclusion and exclusion criteria, 25 patients with facial photoaging were included.
- Trial name
- NCT07107308
- Testing
- Microfocused Ultrasound, Erbium-Doped Fiber Laser
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Pressure Injuries, Caregiver
Evaluate the Feasibility and Effectiveness of a Community-based Care Bundle in Managing and Preventing Pressure Injuries
Community-acquired pressure injuries are pressure injuries that developed outside of hospital, typically in the patient's own home environment. Pressure injuries (PI) used to be commonly known as bedsores or pressure ulcers.
- Conditions
- Pressure Injuries, Caregiver, Community Dwelling Older Adult
- Trial name
- NCT07074743
- Testing
- community-based PI care bundle, Wait-list
- Where
- 2 sites in Singapore
- Volunteers
- 216 people
- Sponsor
- Singapore General Hospital
BREAST CANCER
Impact of Chemo-induced Menopause on Quality of Life in Women <45 Years Old, Diagnosed With Non-metastatic Breast Cancer
Prospective multicenter study, Not on Health Products that evaluates up to 2 and a half years the impact of chemo-induced menopause (CIM) on the functional score of the QLQ-C30 quality of life questionnaire in young women of…
- Trial name
- MENOCOR (NCT02102568)
- Where
- 3 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Jean Perrin
Pressure Ulcer, Pressure Injury
The Use of a Fully Automated Pulsating Support System (CuroCell® A4 CX20) in Pressure Ulcer Prevention and Treatment
Pressure Ulcers are a serious and common problem for residents admitted to long-term care facilities and community care patients.
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Pressure Ulcer, Buttock
- Trial name
- NCT04890678
- Testing
- 22 residentsat risk for PU development, 18 residents at least one PU category III-IV in the sacral area
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent