Clinical trials: Aged Skin
Skin Ageing
Evaluation of Soy Isoflavones on Skin Ageing Parameters
This double-blind, placebo-controlled, randomised pilot trial aims to assess the effect of oral soy isoflavone consumption on skin ageing parameters in post-menopausal women.
- Trial name
- ISOSKIN (NCT06047145)
- Testing
- soy isoflavones
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Breast Cancer, Metastasis
Bevacizumab and Capecitabine in Treatment of Elderly Patients With Metastatic Breast Cancer
This is an open-label, single-arm, multicenter study of capecitabine and bevacizumab administered as first-line treatment of previously untreated elderly patients, older than 70 years, with metastatic or locally recurrent breast…
- Trial name
- NCT01195298
- Testing
- Capecitabine and Bevacizumab
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- South Eastern European Research Oncology Group
Atopic Dermatitis (AD)
A Phase 3 Trial of OPA-15406 Foam in Children and Infants With Atopic Dermatitis
To investigate the superiority of 0.3% OPA-15406 foam to the vehicle in children with atopic dermatitis (AD)
- Trial name
- NCT07184645
- Testing
- OPA-15406, Vehicle
- Where
- Japan
- Volunteers
- 198 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Hyperpigmentation
Clinical Study to Assess Safety, Efficacy and In-Use Tolerability of Oziva Bioactive Gluta Fizzy Effervescent Tablets on Subjects With Facial Dark Spots Such as Pimple Marks, Sunspots, Age Spots and Uneven Skin Tone
This is a randomized, double-blinded, single-centre, two-arms, placebo-controlled, prospective study to evaluate clinical safety, efficacy and in-use tolerability of Test Product i.e.
- Trial name
- NCT07162623
- Testing
- Oziva Bioactive Gluta Fizzy Effervescent Tablets 4.1 g containing Glutathione
- Where
- India
- Volunteers
- 62 people
- Sponsor
- NovoBliss Research Pvt Ltd
Pediculosis
Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice
A comparative safety and efficacy study of NatrOVA Creme Rinse - 1% versus NIX Creme Rinse, under actual use conditions in subjects 6 months of age or greater who are infested with Pediculosis capitis (human head lice).
- Trial name
- NCT00545753
- Testing
- Spinosad, Permethrin 1%
- Where
- 6 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- ParaPRO LLC
Rheumatoid Arthritis
STudying Ageing in Rheumatic Diseases (STAR)
The primary objective of the STAR study is to investigate how measures of disease activity and measures for cognition, physical activity and performance behave in ageing population controls and patients with rheumatoid arthritis…
- Trial name
- NCT05463666
- Testing
- Rheumatoid arthritis
- Where
- Netherlands
- Volunteers
- 840 people
- Sponsor
- Maastricht University Medical Center
Skin Aging
Pilot Study to Evaluate the Safety and the Efficacy of the Matrix and Cells Obtained by the AmeaCell® Device and Intended for the Filling of Wrinkles on the Face.
The purpose of this study is to evaluate the filling using the Matrix and Cells, obtained by the Ameacell® device from autologous adipose tissue and intended for the filling of wrinkles on the face.
- Trial name
- SKINMAT (NCT03529292)
- Testing
- AmeaCell
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Symbioken
Breast Cancer
ExclUsive endocRine Therapy Or Radiation theraPy for Women Aged ≥70 Years Early Stage Breast Cancer
Rationale and relevance for patients and the scientific community. In low risk early stage patients ≥70 years, exclusive radiation therapy (RT) approach might be superior in terms of Health-Related Quality of Life (HRQoL), when…
- Trial name
- EUROPA (NCT04134598)
- Testing
- Breast irradiation (RT), Endocrine Therapy (ET): letrozole, anastrozole, exemestane, tamoxifen
- Where
- Italy
- Volunteers
- 926 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Breast Cancer
Development of a Personalized Discussion Prioritization Tool for Older Adults Considering Adjuvant Chemotherapy for Breast Cancer
The investigators have developed a Discussion Prioritization Tool (DPT) for older adults consider adjuvant chemotherapy that utilizes Conjoint Analysis (CA) methodology and the objective of the current study is to assess…
- Trial name
- NCT05073432
- Testing
- Experimental
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Leukemia, Myelodysplastic Syndromes
DT388IL3 Fusion Protein in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes
RATIONALE: Combinations of biological substances in DT388IL3 fusion protein may be able to carry cancer killing substances directly to the cancer cells.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Blastic Plasmacytoid Dendritic Cell Neoplasm
- Trial name
- NCT00397579
- Testing
- DT388IL3
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Atopic Dermatitis (Eczema)
Safety Study of Roflumilast Cream 0.05% in Infants Aged 3 Months to Less Than 2 Years With Atopic Dermatitis
This study will assess the safety and tolerability of ARQ-151 cream 0.05% applied once a day for 4 weeks in infants with atopic dermatitis (eczema).
- Trial name
- NCT06998056
- Testing
- ARQ-151 cream 0.05%
- Where
- 22 sites in United States, Canada and 1 more
- Volunteers
- 101 people
- Sponsor
- Arcutis Biotherapeutics, Inc.
Breast Neoplasms
GETNA2 Neoadj. TAX+Femara vs Femara in g I/II Breast Cancer
Primarily to evaluate the rates of clinical and radiological response in the 2 groups. Secondarily rate of histological response.
- Trial name
- NCT00617968
- Testing
- DOCETAXEL
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Sanofi
Healthy
Immune Responses After Human Subject Challenge With Sand Fly Bites
Sand flies can carry the infection leishmaniasis (a parasite). The purpose of this study is to evaluate the human immune response to uninfected laboratory raised sand fly bites and select from the immune response to sand fly…
- Trial name
- NCT01289977
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Skin Depressions, Skin Elasticity
A Study to Evaluate the Effect of Juvederm Volift With Lidocaine on Aging Hands in Participants Age 35 and Older
This study will evaluate the effect of Juvederm Volift with Lidocaine, an injectable gel implant, to treat aging hands of participants 35 and older.
- Conditions
- Skin Depressions, Skin Elasticity, Skin Laxity
- Trial name
- NCT04390581
- Testing
- Juvéderm® VOLIFT with Lidocaine
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Allergan
Brow Ptosis, Skin Aging
Single-Session Microfocused Ultrasound, AbobotulinumtoxinA and Temporal Hyaluronic Acid Filler for Non-Surgical Brow Lifting
This observational study describes the results of a routine aesthetic treatment for mild to moderate eyebrow drooping (brow ptosis).
- Conditions
- Brow Ptosis, Skin Aging, Facial Aging
- Trial name
- NCT07894822
- Testing
- Microfocused ultrasound with visualization, AbobotulinumtoxinA, Hyaluronic acid filler
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- Estelab Clinic
Papillomavirus Infections
GARDASIL™ Study in Healthy Females Between 9 and 26 Years of Age in Sub-Saharan Africa (V501-046)
The study is designed to determine the safety, tolerability and immunogenicity of a 3-dose regimen of GARDASIL™ administered to healthy females between 9 and 26 years of age, in Sub-Saharan Africa.
- Trial name
- NCT01245764
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine (GARDASIL™)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Facial Skin Aging, Facial Volume Loss
Comparing Facial Aging Between Identical Twins With 3D Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age.
- Conditions
- Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
- Trial name
- NCT07760532
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ponsky Facial Aesthetics And Plastic Surgery, Llc
Skin, Skin Ageing
Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging.
This clinical study investigates the effects and safety of a topical cosmetic product containing postbiotics (Bifida ferment extract and Pediococcus ferment extract) in women aged 35-60 with visible signs of skin aging.
- Conditions
- Skin, Skin Ageing, Fine Lines, Face Aging/Photo Aging of Moderate Grade
- Trial name
- SkinMeter (NCT07343544)
- Testing
- Active cream
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Skin Aging
Evaluation of the Anti-aging Efficacy of a Novel Skin Health Product
The aim of this study is to investigate the effect of cosmetic products with two different concentrations of the active on skin aging and in acting on the mitochondrial health of skin in comparison to a placebo product.
- Trial name
- NCT05300984
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Chronic Hand Dermatitis
Pimecrolimus Cream 1% in Patients (18 Years of Age and Over) With Mild to Moderate Chronic Hand Dermatitis
Topical steroids are standard of care for Chronic Hand Dermatitis, but long-term use is associated with adverse effects. This study will assess the efficacy and safety of pimecrolimus cream 1% in patients with mild-to-moderate…
- Trial name
- NCT00226707
- Testing
- Pimecrolimus Cream 1%
- Volunteers
- 652 people
- Sponsor
- Novartis