Clinical trials: Aged Skin
Breast Cancer, Lung Cancer
Impact of Geriatrician Interventions on Chemotherapy Delivery in Vulnerable Elderly Oncology Patients
This is a randomized parallel group trial designed to evaluate the impact of implementing geriatrician-prescribed interventions based on the comprehensive geriatric assessment (CGA), on the ability to deliver adequate…
- Conditions
- Breast Cancer, Lung Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- GIVE (NCT02785887)
- Testing
- Geriatrician review
- Where
- 3 sites in Italy
- Volunteers
- 233 people
- Sponsor
- Azienda USL 4 Prato
Tinea Corporis, Tinea Cruris
A Pilot Study to Evaluate the Therapeutic Efficacy of Intra-Lesional Immunotherapy in Patients Aged 10-60 Years With Recalcitrant Tinea Cruris and Corporis
This pilot study will test intra-lesional immunotherapy (MMR vaccine) injections as a treatment for recalcitrant tinea cruris and corporis in patients aged 10-60 years who have not improved with standard antifungal treatments.
- Trial name
- IL-ImmuneRTC (NCT07312604)
- Testing
- Intra-Lesional MMR Immunotherapy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Abeer Mohamed Abdelaziz Elkholy
Skin Ageing
Clinical and Instrumental Evaluation of the Face Biorevitalization Effect With the Medical Device Foliage Hydrofil
this is a Post market, prospective, single arm, clinical investigation. Foliage Hydrofil is a CE marked, class III, resorbable medical device (sterile, non-pyrogenic and physiological gel) to be used for the hydration of the skin…
- Trial name
- NCT07010549
- Testing
- Hyaluronic Acid injections
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Phitogen Beauty Labs SRL
Melanoma
Adding Anakinra and Tocilizumab to Nivolumab and Ipilimumab for the Treatment of Melanoma Patients 50 Years of Age or Older
This phase I trial studies the side effects of adding anakinra and tocilizumab to standard treatment with nivolumab and ipilimumab and to see how well it works in treating melanoma patients who are 50 years of age or older.
- Trial name
- NCT07838974
- Testing
- Anakinra, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Atopic Eczema
A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis
The study will evaluate the safety and effect of pimecrolimus cream 1% on quality of life of caregivers of South African children with mild to moderate atopic dermatitis (AD).
- Trial name
- NCT00484003
- Testing
- Pimecrolimus cream 1%
- Where
- South Africa
- Sponsor
- Novartis
Skin Aging
Effect of Oligopin® on Skin Ageing
Extrinsic or exogenous ageing is caused by repetitive exposure of the skin to harmful agents, while primary cause the exposure to ultraviolet (UV) radiation, known as photoageing, including solar effect.
- Trial name
- OLIGOSKIN (NCT04141059)
- Testing
- Oligopin
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Scleroderma
Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples
The aim is to find the presence of anti vitamin D antibodies in scleroderma patients and compare with control. A second goal is anti vitamin D levels in serum of scleroderma patients in relation to the clinical manifestations of…
- Trial name
- SSc (NCT01553890)
- Testing
- Blood sample
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Breast Cancer, Adjuvant Therapy
Chemotherapy Exemption in Elderly Women With Node-Positive ER+/HER2- Breast Cancer
This study is a prospective, open-label, multicenter, single-arm Phase II clinical trial. Based on the use of CDK4/6 inhibitors in endocrine-sensitive luminal-type (ER+/HER2-) breast cancer, it aims to explore the possibility of…
- Trial name
- ELDER (NCT07826052)
- Testing
- CDK4/6 inhibitor, Endocrine Therapy (Optional)
- Volunteers
- 494 people
- Sponsor
- Fudan University
Dermatitis, Dermatitis, Atopic
Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects
B7451014 is a Phase 3 study to investigate PF-04965842 in patients aged 12 years and over with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis.
- Conditions
- Dermatitis, Dermatitis, Atopic, Eczema, Skin Diseases
- Trial name
- NCT03627767
- Testing
- PF-04965842 100 mg, PF-04965842 200 mg
- Where
- 235 sites in United States, Argentina and 19 more
- Volunteers
- 1,235 people
- Sponsor
- Pfizer
Premature, Parent-Child Relations
Effect of Parental Enteral Nutrition on Quality Of Parent-Child Interactions
Studies underline both the importance of the link and contact that occurs in the earliest days of life and the need to involve parents early with their premature child.
- Trial name
- PREMIAM (NCT05313464)
- Testing
- parent-pushed enteral feeding, syringe-push enteral feeding
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Venous Leg Ulcer
Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population
This study is designed to assess the clinical effectiveness of Membrane Wrap, a human amniotic membrane for the management of difficult to heal partial- or full-thickness venous leg ulcers (VLUs)
- Trial name
- NCT06544564
- Testing
- Membrane Wrap™, Standard of Care
- Where
- 9 sites in United States
- Volunteers
- 30 people
- Sponsor
- BioLab Holdings
Breast Cancer, Prostate Cancer
A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer
The purpose of this study is to examine whether psychoeducation counseling for older cancer patients undergoing treatment is feasible and worthwhile.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Lymphoma Cancer
- Trial name
- NCT00984321
- Testing
- group intervention and questionnaires, individual phone intervention and questionnaires, expressive writing (arm will not be include in the randomization)
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Breast Neoplasms
Imaging Characteristics of Breast Cancer in Women Under 40 Years of Age
To evaluate if there is any imaging characteristic of breast cancers in women younger than 40 years of age.
- Trial name
- NCT00155038
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer, Colorectal Cancer
Geriatric Assessment and Promotores (GAP) Pilot Feasibility Study
The goal of this clinical trial is to test a new way to help older adults who have had cancer. The researchers want to see if a program that assesses participants health and aging is achievable and makes a difference.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- GAP (NCT06125145)
- Testing
- Geriatric Assessment and Promotora Coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Tinea Capitis
Safety and Efficacy of NAFT900 in Children With Tinea Capitis
A Double-Blind, Randomized, Vehicle-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of NAFT-900 in Children Aged 6 to < 13 Years with Tinea Capitis
- Trial name
- NCT02658292
- Testing
- Naftifine hydrochloride foam, 3%, Vehicle
- Sponsor
- Merz North America, Inc.
Skin Aging, Facial Asymmetry
Comparison of an Office-based Limited Facelift and Hospital-based Full Facelift
To compare safety, patient satisfaction, and technical correction between a limited and full facelift, patients meeting strict clinical and safety criteria for both types of facelift will be randomly assigned to have one of these…
- Conditions
- Skin Aging, Facial Asymmetry, Aging Problems
- Trial name
- COAL2 (NCT05419609)
- Testing
- Limited facelift, Full facelift, FACE-Q | Aesthetics - Satisfaction With Lower Face and Jawline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dufresne, Craig, MD, PC
Hereditary Angioedema
A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children
The main aims of this study are to learn how lanadelumab moves through a child's body and if the children have any medical problems from lanadelumab.
- Trial name
- SPRING (NCT04070326)
- Testing
- Lanadelumab
- Where
- 17 sites in United States, Canada and 3 more
- Volunteers
- 21 people
- Sponsor
- Shire
Dermatitis Atopic
A Study of Long-term Effect of Dupilumab on Skin Barrier Function in Pediatric Participants With Atopic Dermatitis
This is a 2-year, open-label, exploratory study with a 4-week screening period and a 104-week treatment phase designed to investigate dupilumab's long-term effect on skin barrier function as measured by transepidermal water loss…
- Trial name
- PELISTAD-EX2 (NCT05983068)
- Testing
- dupilumab
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 48 people
- Sponsor
- Sanofi
Dermatitis Atopic
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)
This is a parallel group, Phase 3, multinational, multicenter, randomized, double-blind, placebo-controlled, 3-arm monotherapy study for treatment of participants diagnosed with moderate to severe atopic dermatitis (AD), whose…
- Trial name
- NCT06181435
- Testing
- Amlitelimab
- Where
- 142 sites in United States, Argentina and 14 more
- Volunteers
- 589 people
- Sponsor
- Sanofi
Breast Cancer, Lung Cancer
Docetaxel in Treating Older Patients With Metastatic Breast, Lung, or Prostate Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel, use different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Breast Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00059943
- Testing
- docetaxel
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center