Clinical trials: Aged Skin
Cutaneous Mastocytosis, Systemic Mastocytosis
Mastocytosis From Pediatric Age to Adulthood: Local Registry of Cutaneous and Systemic Mastocytosis
Given the renewed focus on mastocytosis (recognized in Italy as a rare disease since 2018) and emerging clinical and immunogenetic knowledge, and considering the rarity of the disease and limited understanding of its progression…
- Trial name
- MaRe (NCT07142473)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Irritation/Irritant
Study in Elderly Alzheimer's Patients to Assess Skin Tolerability, Irritation With 3, 7-Day Applications of DTP-System
This study is designed to assess skin tolerability, skin irritation, and adhesion of the 350 mg Donepezil Transdermal Patch (DTP-system), following 3, 7-day applications to 3 specific areas of the body (upper back, upper middle…
- Trial name
- DTP-System (NCT00916383)
- Testing
- 350 mg Donepezil Transdermal Patch
- Where
- 7 sites in United States
- Volunteers
- 49 people
- Sponsor
- Teikoku Pharma USA, Inc.
Rheumatoid Arthritis
Safety and Effectiveness of Biological DMARDs in Elderly Patients With Rheumatoid Arthritis
Study objectives 1. Comparison of drug persistency rates between elderly RA patients and young RA patients with biological DMARDs 2.
- Trial name
- NCT01685918
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Hanyang University
Skin Aging
Evaluation of the Skin-Beautifying Effects of Collagen Drinks
This study aims to investigate the skin beauty benefits of collagen drinks in healthy individuals.
- Trial name
- NCT06900660
- Testing
- Collagen Drinks
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Simply Plus Co., Ltd.
Breast Cancer, Lung Cancer
Impact of Geriatrician Interventions on Chemotherapy Delivery in Vulnerable Elderly Oncology Patients
This is a randomized parallel group trial designed to evaluate the impact of implementing geriatrician-prescribed interventions based on the comprehensive geriatric assessment (CGA), on the ability to deliver adequate…
- Conditions
- Breast Cancer, Lung Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- GIVE (NCT02785887)
- Testing
- Geriatrician review
- Where
- 3 sites in Italy
- Volunteers
- 233 people
- Sponsor
- Azienda USL 4 Prato
Skin Aging, Photoaging of Skin
Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules
This is a placebo-controlled blinded clinical evaluation of day and night skin care creams supplemented by Medicell Technology's composition of defensins and supportive molecules determine the skin hydration and anti-aging…
- Trial name
- NCT02765763
- Testing
- 2-Minute Reveal Masque, 24/7 Barrier Repair Cream, 8-in-1 BioSerum
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Advanced Dermatology
Skin Aging
Comparison of Redermic, Rejuva-A and Combination of Both Redermic and Rejuva-A in Subjects With Signs of Aging
Facial skin aging is a complex process combining factors such as sun exposure, smoking and those that are believed to be inherited.
- Trial name
- NCT00974480
- Testing
- Redermic, Tretinoin (Rejuva-A)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Skin Aging
A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging
A clinical study with approximately 40 subjects, aged 35-65 years of age, who must have crow's feet and at least one other type of facial fine lines/wrinkles in order to evaluate the efficacy of Activated Silk™ 27P-α to improve…
- Trial name
- NCT06804759
- Testing
- Investigational Facial Serum #1, Investigational Facial Serum #2, Investigational Facial Serum #3
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Victoria Collotta
Breast Cancer
'ADVANCE' (A Pilot Trial)
This study is being conducted to carefully study how chemotherapy is tolerated in group of patients age 70.
- Trial name
- NCT03858322
- Testing
- Paclitaxel, Cyclophosphamide, Carboplatin
- Where
- 5 sites in United States
- Volunteers
- 41 people
- Sponsor
- Dana-Farber Cancer Institute
Tuberculosis
Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.
This is a randomized, blind, positive-controlled study to explore the skin test dosage of recombinant mycobacterium tuberculosis fusion protein ( EEC) in the population aged 18 to 65 years old , and to further evaluate the safety…
- Trial name
- NCT06305104
- Testing
- 2.5μg/ml EEC, 5μg/ml EEC, 5 unit（U） EC
- Where
- 6 sites in China
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Chengdu CoenBiotech Co., Ltd
Skin Aging
Comparison of Outcome Parameters in Laser Rhytide Treatment
We previously published a comparative split-face study which has shown a significant, albeit moderate, effect of ablative fractional laser treatment.
- Trial name
- NCT00994474
- Testing
- Fractional carbon dioxide laser treatment, Fractional Er:YAG laser treatment
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Laserklinik Karlsruhe
Hereditary Angioedema
Safety of Ruconest in 2-13 Year Old Hereditary Angioedema (HAE) Patients
This open-label study is being conducted to confirm the safety, pharmacokinetic profile and efficacy of Ruconest at a dose of 50 U/kg when used for the treatment of acute angioedema attacks in patients, from 2 up to and including…
- Trial name
- NCT01359969
- Testing
- rhC1INH
- Where
- 16 sites in United States, Czechia and 8 more
- Volunteers
- 57 people
- Sponsor
- Pharming Technologies B.V.
Periorbital Hollowing, Skin Aging
Clinical Research on Deep-Plane Rejuran S Injection for Improvement in the Apperance of Periorbital Hollowing Using a Cannula Technique
The goal of this clinical study is to learn whether DOT PN (Rejuran S), a polynucleotide injectable gel, improves periorbital hollowing (a sunken look around the eyes) in adults aged 25 to 65 years when injected into the deep…
- Trial name
- NCT07912814
- Testing
- DOT PN (Rejuran S)
- Where
- 3 sites in Malaysia, Singapore and 1 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PharmaResearch Co.,Ltd
Breast Cancer
Young Breast Cancer Survivors Study
Despite significant overall reductions in mortality rates for breast cancer over the past decade, both incidence and mortality rates have steadily climbed in adults diagnosed before age 50.
- Trial name
- YBCSS (NCT05981716)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- University of South Carolina
Juvenile Idiopathic Arthritis (JIA)
OLE Study With Filgotinib in JIA
This OLE study is designed to evaluate long-term safety, tolerability, and efficacy of filgotinib in patients with polyarticular or systemic juvenile idiopathic arthritis (pJIA-sJIA) who have completed the treatment…
- Trial name
- OLE JIA (NCT07553182)
- Testing
- Filgotinib
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 80 people
- Sponsor
- Alfasigma S.p.A.
Scabies
PK and Safety Study of Natroba Topical Suspension 0.9% in Subjects 1 Month to 3 Years 11 Months of Age With Scabies
A population of approximately 50 pediatric subjects will be enrolled to assess the PK of spinosad and benzyl alcohol for 3 hours following a single, full-body topical application (open label) on a single in-clinic visit (Day 1…
- Trial name
- NCT05310734
- Testing
- Spinosad Topical
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cipher Pharmaceuticals Inc.
Face Skin Photoaging
Face Photoaging: Efficacy and Tolerance Evaluation of an Intradermal Injective Treatment
Efficacy and tolerance evaluation of an intradermal injective treatment
- Trial name
- NCT03274232
- Testing
- SUNEKOS ® 200
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Incontinence-associated Dermatitis
Prevention of Incontinence-associated Dermatitis
Incontinence-associated dermatitis (IAD) is an inflammation of the skin caused by prolonged direct contact of the skin with urine and/or stool. Elderly and care-dependent people are often affected by this type of inflammation.
- Trial name
- PID (NCT05403762)
- Testing
- ESENTA™ Skin Barrier Spray (ConvaTec, UK), Hydrophobes Basisgel DAC
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Ostomy, Living in Roskilde County
Skin Problems in Ostomy Patients: An Epidemiological Study
Peristomal skin complications are thought to be common but the exact frequency and cause of these complications are unknown. We have sought to document the incidence of cutaneous peristomal problems and to find risk factors that…
- Conditions
- Ostomy, Living in Roskilde County, Persons More Than 18 Years of Age, Willingness to Participate
- Trial name
- NCT00391508
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Aging Skin
Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment
Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days.
- Trial name
- NCT06431282
- Testing
- CO2 laser + HA, Thulium laser + HA
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf