Clinical trials: Ageing
Aging
Ambient Independence Measures for Guiding Care Transitions
The purpose of this study is to learn more about how to maintain health and independence for seniors by developing tools that collect data constantly from their home.
- Trial name
- AIMs (NCT02566239)
- Testing
- Share activity data with care team
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hearing Loss
Evaluation of the Benefits for Overall Health Following Cochlear Implant Treatment in the Elderly Population
The purpose of this study is to show that cochlear implant treatment improves the overall health related quality of life and general well-being in elderly individuals.
- Trial name
- NCT03072862
- Testing
- Commercial Nucleus Cochlear Implant Systems
- Where
- 8 sites in France, Israel and 2 more
- Volunteers
- 100 people
- Sponsor
- Cochlear
Aging, Sarcopenia
Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals
Nitrate is a naturally-occurring substance found in foods, especially green leafy vegetables and beets. Increasing nitrate intake (by drinking beetroot juice (BRJ) has been shown to improve muscle function young and middle-aged…
- Trial name
- NCT03595774
- Testing
- Beet root juice
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Indiana University
Ageing
Effect of a Transcutaneous Electrical Nerve Stimulation (TENS) Device on Overall Facial Appearance
Safety and clinical performance of the BMR Face device (manufactured by Bio-Medical Research)
- Trial name
- NCT01740440
- Testing
- BMR Face
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bio-Medical Research, Ltd.
Mild Cognitive Impairment, Healthy Aging
SHARE(D) Stage II: Alzheimer's Risk Disclosure Protocol Piloting
The goal of this study is to test efficacy and safety of person-centered, culturally-informed protocols for disclosure of different combinations of Alzheimer's dementia risk factors.
- Trial name
- SHARE(D) (NCT04309500)
- Testing
- Personalized DAT Risk Disclosure Protocol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy Aging
What Makes People Better at Naming Pictured Objects
This study is being conducted to learn more about how mindful breathing might be related to the ability to produce names for pictured objects.
- Trial name
- NCT06405893
- Testing
- Mindful breathing exercise
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Colorado Springs
Depressive Disorder
Depressed Mood Improvement Through Nicotine Dosing 2
Deficits in cognitive control are core features of late-life depression, contributing both to emotion dysregulation and problems with inhibiting irrelevant information, conflict detection, and working memory.
- Trial name
- DepMIND2 (NCT04433767)
- Testing
- Transdermal Nicotine patch
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Vanderbilt University Medical Center
Aging
Mindfulness Training in Healthy Older Veterans
Evidence shows the positive effects of Brain Health \& Wellness classes in younger individuals. The proposed study investigates the usefulness of these classes in older Veterans aged 50-85.
- Trial name
- MTGHOV (NCT02816723)
- Testing
- Mindfulness-based Stress Reduction, Brain Health
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Skin Aging
Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
The purpose of this study is to determinate whether Xeomin® (Botulinum toxin Type A) is safe, effective and tolerable in woman aged 30 to 50 years old for treatment of mild, moderate or severe expression lines (wrinkles) in the…
- Trial name
- XEO-001/07 (NCT00986570)
- Testing
- Botulinum Toxin A
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Aging-related Inflammation in HIV-infected Patients
Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen
Physicians in charge of HIV-infected patients are increasingly being faced to previously unrecognized comorbid conditions such as atherosclerosis and cardiovascular events, loss of renal function, osteopenia/osteoporosis and bone…
- Trial name
- NCT02577042
- Testing
- Raltegravir, PI-based regimen, Atorvastatin
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Aging, Obesity
Effects of Testosterone Gel on Carbohydrate and Lipid Metabolism In Elderly Obese Men
A. HYPOTHESES: In older men low testosterone levels, abdominal obesity and elevated fasting insulin who are at risk for the cardiovascular complications such as heart attack and stroke. 1.
- Conditions
- Aging, Obesity, Insulin Resistance, Hypogonadism
- Trial name
- NCT00365794
- Testing
- Topical testosterone gel 10 g/day
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Physical Activity, Aging
A Study of Physical Activity paTTerns and Major Health Events in Older People With Implantable Cardiac Devices
An observational study of physical activity patterns in 150 older adults with cardiac implantable electronic devices (CIED)
- Conditions
- Physical Activity, Aging, Cardiac Disease
- Trial name
- PATTErn (NCT03544424)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 183 people
- Sponsor
- University of Manchester
Sedentary Lifestyle, Self Efficacy
Planning the Next Steps: Using an Implementation Intention Approach to Increase Daily Walking
The study goal is to design an intervention utilizing implementation intentions to help participants prospectively plan and visualize ways to increase activity for the next day among working adults who do not currently exercise…
- Conditions
- Sedentary Lifestyle, Self Efficacy, Control Locus
- Trial name
- NCT03124563
- Testing
- Control Group, Implementation Intention Condition
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Depressive Symptoms
Nurse-Led Interprofessional Mental Health Promotion Intervention for Older Home Care Clients
Objective: The objective of this study is to evaluate the feasibility, acceptability and effectiveness of a 6-month nurse-led, interprofessional mental health promotion intervention aimed at older home care clients with…
- Trial name
- NCT01407926
- Testing
- Nurse-Led Mental Health Promotion Intervention
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- McMaster University
Skin Aging
Safety and Efficacy Evaluation of Erbium Treatment
The purpose of this research study is to evaluate the safety and effectiveness of erbium lasers for dermatological cosmetic procedures.
- Trial name
- NCT00766376
- Testing
- Erbium laser
- Where
- 5 sites in United States
- Volunteers
- 151 people
- Sponsor
- Palomar Medical Technologies, Inc.
Resilience, HIV-1-infection
Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV
This study will examine the mechanisms and efficacy of a resilience building intervention in older people living with HIV.
- Conditions
- Resilience, HIV-1-infection, Stress, Psychological
- Trial name
- RISE+ (NCT05314088)
- Testing
- RISE+, Stress Reduction Control
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Alabama at Birmingham
Aging, Heart Failure With Preserved Ejection Fraction
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure
In a randomized controlled trial, to study the utility of inspiratory muscle training (IMT) to improve functional outcomes in adults aged ≥70 years with heart failure (HF) who have been referred to palliative care for end-stage…
- Conditions
- Aging, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Frailty
- Trial name
- RETRO (NCT06576297)
- Testing
- Inspiratory Muscle Training (IMT), Standard of Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Aging
A Social Media Game to Increase Physical Activity Among Older Adult Women
This study will test the effects of a social media game on the physical activity of older adult women. The game will consist of playful weekly challenges that require sharing photographs on a private social media group and also…
- Trial name
- CHALLENGE (NCT04095923)
- Testing
- Social media game, Standard self-regulation
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Aging, Activity
Return to Everyday Activities in the Community and Home
The purpose of this study is to test feasibility for the delivery and perceptions of a lifestyle model for middle-aged and older adults by involving participants in its development.
- Conditions
- Aging, Activity, Lifestyle
- Trial name
- REACH (NCT02786394)
- Testing
- REACH
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Skin Laxity
Radio Frequency Microneedling for Suprapatellar Skin
The human skin aging process is characterized by thinning dermis, atrophy of the extracellular matrix, and reduced collagen synthesis.
- Trial name
- NCT03507036
- Testing
- Profound system
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center