Clinical trials: Ageing
Aging Problems
Effect of a New HA Filler in Correcting Nasolabial Fold
The investigators aimed to evaluate the efficacy and safety of new HA filler for nasolabial fold correction
- Trial name
- NCT06574750
- Testing
- CUREAⓇ (ARIBIO, Ltd., Seoul, Republic of Korea), JuvedermⓇ (Q-Med AB, Uppsala, Sweden)
- Where
- South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Healthy
Application of Deuterated Water (D2O) to Define the Etiology of Musculoskeletal Decline in Ageing and the Efficacy of Nutritional Supplementation
Maintaining muscle mass and function is important in healthy ageing to maintain quality of life. Loss of muscle mass is major problem, as beyond the age ~50, muscle mass declines by ~1-2% a year.
- Trial name
- NCT02505438
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sleep, Health Promotion
Aging Well, Sleeping Efficiently: Protecting Health In Later Life
The purpose of this study is to see whether protecting sleep quality in later life is important in continued healthy aging. The value of education in healthy sleep practices along with reducing time in bed each night by going to…
- Trial name
- AgeWise (NCT00177385)
- Testing
- Modest sleep deprivation with sleep hygiene education
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Aging
The Eggs and actiVity in hEalth agiNg Pilot (EVEN-P) Trial in Older Persons
Two of the most effective lifestyle-based approaches to reduce the risk of adverse health events and enhance quality of life with aging are exercise and a healthy diet.
- Trial name
- EVEN-P (NCT04264013)
- Testing
- Exercise, Exercise plus diet (egg)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Ageing
Study to Assess the Effect of Leucine Along With Resistance Exercise on Muscle Strength and Quality of Life in Elders
The purpose of this study is to determine whether a nutritional supplement with an amino acid called leucine along with resistance exercise are effective in the improvement of muscle strength and quality of life in elderly people.
- Trial name
- NCT00929929
- Testing
- L-leucine., Maltodextrin., Exercise program.
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Skin Health
An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Cream on Skin Health and Signs of Aging
This is a virtual, single-group clinical trial that will last 8 weeks. Participants will use the Manuka Health Eternal Renewal Regenerating Face Cream with Royal Jelly and Bee Venom twice daily and complete questionnaires at…
- Trial name
- NCT06148766
- Testing
- Manuka Health Eternal Renewal Regenerating Face Cream with Royal Jelly and Bee Venom
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Manuka Health
Digital Health Literacy, Healthy Aging
Effectiveness of Intensive Tutoring vs. Flexible Self-Learning on Digital Health Literacy and Self-Efficacy for "My Health Bank" App Use Among Adults Over 50
The purpose of this study is to evaluate the effectiveness of two different educational models in improving the use of the "My Health Bank" App (a Personal Health Record system in Taiwan) among adults aged 50 and older.
- Trial name
- NCT07515495
- Testing
- AI-Collaborative eHealth Education
- Where
- 2 sites in Taiwan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
COPD
Novel Predictors of Premature Aging in COPD Patients
•Examine whether COPD is associated with accelerated aging using a biological marker of aging and dermatological score
- Trial name
- NCT06019286
- Testing
- SCINEXA score
- Volunteers
- 100 people
- Sponsor
- Assiut University
Aging
Study Human Digital Support Transitional Care
The purpose of the study is to compare the effectiveness of Divomed in organising complex hospital discharges with a conventional organisation.
- Trial name
- SUNH-ST (NCT06354166)
- Testing
- Unscheduled hospital admissions
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Divoluci
Establish the Amount of CENPV Protein in Human Oocytes as a Diagnostic Tool Against Damage Caused by Ageing or by the Procedure of Vitrification of Oocytes, Advance Maternal Age
CENP-V as a Potential Diagnostic Marker of Damage in Human Oocytes
Proper chromosome segregation is essential to avoid aneuploidy, yet in mammalian oocytes it progressively fails in an age-dependent manner.
- Conditions
- Establish the Amount of CENPV Protein in Human Oocytes as a Diagnostic Tool Against Damage Caused by Ageing or by the Procedure of Vitrification of Oocytes, Advance Maternal Age, Vitrification and Thawing
- Trial name
- CENP-PILOT (NCT06788379)
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Vida Recoletas Sevilla
Wellness Programs, Hospitalization
The Effectiveness of Peer-to-Peer Community Support to Promote Aging in Place
The investigators' overall objective is to evaluate the effectiveness of peer-to-peer support programs in preventing the necessity of acute health care and nursing home services for older adult populations and in promoting their…
- Conditions
- Wellness Programs, Hospitalization, Emergency Room
- Trial name
- NCT02308696
- Testing
- Peer-to-Peer Support, Standard Community Services
- Where
- 5 sites in United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes, Prediabetes
Study of Diabetes' Risk Factors and Accelerated Aging According to Socio-economic Status in a Population From the North of France - 3-year Follow-up
Populations in precarious situations or with low socio-economic status are at greater risk of diabetes and accelerated ageing. Depending on the population studied, the factors that may explain these health inequalities are not…
- Trial name
- PrévenDIAB 2 (NCT06866002)
- Testing
- Biological analysis, Physical examination and Questionnaires, Physical examination and Questionnaires
- Where
- France
- Volunteers
- 2,011 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Frailty Syndrome, Aging
Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)
This is a Phase I, open-label, non-randomized clinical trial to evaluate the safety and preliminary efficacy of adipose-derived mesenchymal stem cell secretome capsules (VinVital) in patients with frailty syndrome.
- Trial name
- VinVital (NCT07856602)
- Testing
- VinVital
- Volunteers
- 20 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Parkinson's Disease (PD), Healthy Aging
Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease
This study will evaluate whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and in individuals living with Parkinson's disease, populations at high risk of falls and mobility…
- Trial name
- NCT07567482
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre intégré de santé et de services sociaux de l'Outaouais
Delirium, Aging
MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care
This will be the first large cohort study to define the epidemiology of and identify modifiable risk factors for long-term CI and functional deficits of ICU survivors.
- Conditions
- Delirium, Aging, Dementia
- Trial name
- NCT00400062
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- VA Office of Research and Development
Fine Lines, Wrinkles
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin…
- Conditions
- Fine Lines, Wrinkles, Photoaging
- Trial name
- NCT04545970
- Testing
- Facial cleanser, Facial moisturizer, Sunscreen
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Fall Injury, Age Problem
CatchU: A Quantitative Multisensory Falls-Assessment Study
The ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. To date, only a few studies have investigated the clinical translational value of multisensory…
- Conditions
- Fall Injury, Age Problem, Well Aging, Sensory Disorders
- Trial name
- CatchU (NCT05544760)
- Testing
- CatchU Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Healthy Older Adults
Transcranial Alternating Current Stimulation for the Improvement of Episodic Memory in Healthy Older Adults
Memory complaints are a common symptom among Subjective Cognitive Decline, Mild Cognitive Impairment and Alzheimer disease. Indeed, episodic memory and Alzheimer disease are highly sensitive to aging.
- Trial name
- NCT06284720
- Testing
- Gamma tACS (40 Hz) over the precuneus
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Aging
Mindfulness Meditation in Older Adults
The purpose of this study is to test if an 8-week mindfulness meditation training (vs a wait-list control condition) program reduces neurobehavioral reactivity and improves affect regulation in a sample of older adults, as…
- Trial name
- MIND (NCT01532596)
- Testing
- Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy Aging, Cognitive Change
A Digital Active Aging Training Program for Older Adults
The proposed project aims to develop and validate a multi-dimensional digital active aging program integrated with resilience to promote the biopsychosocial functions of older adults aged 60, including Chinese older immigrants in…
- Conditions
- Healthy Aging, Cognitive Change, Psychological Stress, Loneliness
- Trial name
- AAT (NCT06270862)
- Testing
- Resilience training, cognitive training, physical exercise
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University