Clinical trials: Ageing
Aging
Ambient Independence Measures for Guiding Care Transitions
The purpose of this study is to learn more about how to maintain health and independence for seniors by developing tools that collect data constantly from their home.
- Trial name
- AIMs (NCT02566239)
- Testing
- Share activity data with care team
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Older Adults, Mental Health
The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)
The goal of this clinical trial is to learn if the BE WITH (Belonging through Empathy With Intentional Targeted Helping) innovation delivered to older adults improves their mental health.
- Conditions
- Older Adults, Mental Health, Depression, Loneliness
- Trial name
- BE_WITH (NCT07204444)
- Testing
- standardized and manualized warm calls from providers trained in the BE training, standardized and manualized warm calls from providers trained in the BE training + ASIST training
- Where
- United States
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging, Cognitive Change
Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community
The goal of this study is to test the feasibility of launching a personalized digital health assessment and remediation program for the older adults in senior living communities based upon an initial characterization of these…
- Trial name
- ACCT (NCT04905849)
- Testing
- Adaptive Cognitive Control Trainer (ACCT), Active Control App
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aging
CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
The purpose of this study is to test the hypothesis that two years of sustained 25% caloric restriction (CR) in men age 21-50 (inclusive) and women age 21-47 (inclusive) will slow aging and protect against age-related disease…
- Trial name
- NCT00427193
- Testing
- Caloric Restriction (CR), Control
- Where
- 3 sites in United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Duke University
Sedentary Lifestyle
A "Stand Up and Move More" Intervention for Older Adults
The purpose of the expanded study is to examine the effectiveness of a "Stand Up and Move More" intervention to reduce sedentary behavior in older adults from underserved communities.
- Trial name
- NCT03412084
- Testing
- Stand up and move more
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aging, Wrinkle
Restylane Refyne for Correction of Horizontal Neck Rhytides
Subjects with grades ranging from 1---3 on the Transverse Neck Line Scale, will be randomized to receive up to 1cc of Restylane Refyne on one side of their neck utilizing a cannula and up to 1cc of Restylane Refyne on the other…
- Conditions
- Aging, Wrinkle, Rhytides
- Trial name
- NCT04162496
- Testing
- Restylane Refyne
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Siperstein Dermatology
Skin Aging
Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
The objective of this POC clinical study is to evaluate the moisturising effects on fine lines and wrinkles, texture, barrier function, hydration and elasticity delivered by 4 weeks of twice daily application of the test product…
- Trial name
- NCT03180645
- Testing
- Test product (Moisturising cream), Positive control (Commercial market place moisturising cream), No treatment
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Schizophrenia, Aging
Functional Rehabilitation for Older Patients With Schizophrenia
Aging and psychosis are major priority areas for VA. This project is a continuation of a Merit Review Program, in which we developed, manualized and conducted randomized controlled trials of a novel psychosocial rehabilitation…
- Trial name
- FROPS (NCT00712075)
- Testing
- CBSST+PDA, Cognitive Behavioral Social Skills Training, PDA-only
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- US Department of Veterans Affairs
HIV Positive, Ageing
The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'
The purpose of this study is to identify medical conditions that may cause particular problems to individuals receiving care for HIV infection over the age of 50.
- Trial name
- POPPY (NCT01737047)
- Where
- 8 sites in Ireland, United Kingdom
- Volunteers
- 1,377 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Delirium, Alzheimer Disease
Improving the Recovery and Outcome Every Day After the ICU
Primary Specific Aim: Determine the effect of the combined physical exercise and cognitive training on the cognitive function of ICU survivors aged 50 and older.
- Trial name
- IMPROVE (NCT03095417)
- Testing
- Physical Exercise Intervention, Cognitive Training Intervention, Stretching Control
- Where
- 6 sites in United States
- Volunteers
- 249 people
- Sponsor
- Indiana University
Sedentary Lifestyle
Aerobic Exercise and Cognitive Training in Older Adults
The purpose of this study is to examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults.
- Trial name
- NCT02787655
- Testing
- Aerobic exercise + Cognitive Training Group, Cognitive training Only
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
HIV
Strength Training and Endurance Exercise for LIFE
Research is needed to determine safe and effective exercise rehabilitation programs to prevent and improve physical disability in older adults living with HIV. This problem is of great importance to the VA.
- Trial name
- STEEL (NCT02101060)
- Testing
- exercise
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Scarring, Skin Aging
Open-label, Prospective, Multicenter Study to Evaluate the Cutera Excel V™ Laser and a Micro-Lens Array Attachment
Open-label, Prospective, Study to Evaluate the Cutera excel V laser at 532 nm in a low fluence, high repetition rate mode and the Micro-Lens Array attachment used with excel V laser at 1064 nm and 532 nm for the improvement of…
- Trial name
- NCT03424148
- Testing
- Excel V™ Laser & Micro-Lens Array Attach
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Aging
Optimizing tDCS to Improve Dual Task Gait and Balance
The objective of this study is to determine the acute effects of single sessions of optimized tDCS, conventional tDCS, and sham stimulation on dual task standing and walking in older adults who are free of overt disease yet who…
- Trial name
- OptiStim (NCT04295798)
- Testing
- Conventional tDCS, Optimized tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Dementia, Alzheimer Disease
The Cognition and Flow Study
About the research There are currently 850,000 people living with dementia in the United Kingdom. It is now understand that Alzheimer's disease (AzD) can result from damaged blood vessels in the brain.
- Conditions
- Dementia, Alzheimer Disease, Mild Cognitive Impairment, Aging
- Trial name
- NCT03656107
- Testing
- Cognitive Training
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Dementia, Alzheimer Disease
Aging Brain Care Virtual Program
The program involves a virtual intervention to be delivered by RN or SW care coordinators over one year. Every care partner will receive monthly virtual visits during the first 3 months and then quarterly or more depending on…
- Trial name
- ABCV (NCT06245499)
- Testing
- Aging Brain Care Virtual Program
- Where
- United States
- Volunteers
- 987 people
- Sponsor
- Indiana University
Mitochondrial Function, Physical Function
Resveratrol to Enhance Vitality and Vigor in Elders
Resveratrol, a compound found in red wine and dark-skinned grapes, will improve the function of mitochondria (energy producing components) within the leg muscles of moderate functioning older adults.
- Trial name
- REVIVE (NCT02123121)
- Testing
- Resveratrol 1000 mg/day, Resveratrol 1500 mg/day, Vegetable cellulose
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Presbycusis, Aging
At-home Auditory Training Clinical Trial
The purpose of this study is to investigate the effectiveness of an auditory training program used at home with the subject's own hearing aids.
- Conditions
- Presbycusis, Aging, Hearing Loss
- Trial name
- Training (NCT01950013)
- Testing
- Auditory training program
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Aging Well
Immersive Technology and Virtual Reality as a Health Support Tool in a Residence for the Elderly
The purpose of this clinical trial is to learn more about the potential for using virtual reality in older adults living in residences for elderly to maintain health (physical activity, cognitive activity, social behaviors).
- Trial name
- NCT06117319
- Testing
- Individual assistance Virtual reality training sessions, Collective assistance Virtual reality training sessions
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- TOPMED
Mid-facial Volume Deficit Related to Aging
Safety and Effectiveness of Juvéderm® VOLUMA XC Injectable Gel for Cheek Augmentation
Multicenter, single-blind, randomized, "no-treatment" control study to demonstrate the safety and effectiveness of VOLUMA XC for deep injection for cheek augmentation to correct age-related volume deficit in the mid-face.
- Trial name
- NCT00978042
- Testing
- Juvéderm® VOLUMA XC
- Where
- 2 sites in United States, Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Allergan