Clinical trials: Aggressive Behaviour
Aggressive Periodontitis
Frequency Of MCP-1 And CCR2 Gene Polymorphisms And Its Effect On Gene Expression In Patients With AgP
The aim of this study is to estimate genetic impact of MCP-1 -2518 and its receptor CCR2 -190 polymorphisms on AgP patients among Turkish individuals and whether MCP-1 genotype effects mRNA levels of Peripheral Blood Mononuclear…
- Trial name
- NCT02817568
- Testing
- Drawing Blood
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
De-escalation Skills
Evaluation of Training in De-escalation
The purpose of the study is to evaluate one of the chapters in the new national Norwegian training manual (MAP). The chapter that is selected to be evaluated is the chapter on de-escalation.
- Trial name
- NCT03924141
- Testing
- Training in de-escalation
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Bergen University College
AIDS-Related Diffuse Large B-cell Lymphoma, AIDS-Related Non-Hodgkin Lymphoma
Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
This phase I trial evaluates the side effects and usefulness of axicabtagene clioleucel (a CAR-T therapy) and find out what effect, if any, it has on treating patients with HIV-associated aggressive B-cell non-Hodgkin lymphoma…
- Conditions
- AIDS-Related Diffuse Large B-cell Lymphoma, AIDS-Related Non-Hodgkin Lymphoma, HIV Infection, Recurrent Diffuse Large B-Cell Lymphoma
- Trial name
- NCT05077527
- Testing
- Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- AIDS Malignancy Consortium
Mature B-cell Non-Hodgkin Lymphoma
Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents
The purpose of this study is to test whether intensive chemotherapy combined with early, adequate, and intensive use of Rituximab for aggressive B-NHL in children and adolescents can improve the EFS and OS compared with the…
- Trial name
- B-NHL (NCT07168980)
- Testing
- Cyclophosphamide, Vincristine, Cytarabine, Doxorubincin, Prednisone, Drug: Ifosphamide, Etoposide, Methotrexate, Vincristine, Prednisone, Ifosphamide, Etoposide, Methotrexate, Vincristine, Prednisone
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Children's Cancer Group, China
Aggression, Psychosocial Problem
The Added Value of an Internet-based Intervention for Treatment of Forensic Psychiatric Outpatients
Even though internet-based interventions have been used in treatment of forensic psychiatric outpatients for over ten years, no robust research into their effectiveness has taken place.
- Conditions
- Aggression, Psychosocial Problem, Forensic Psychiatry, Internet-based Intervention
- Trial name
- NCT05711342
- Testing
- Aggression, Treatment as usual
- Where
- 4 sites in Netherlands
- Volunteers
- 128 people
- Sponsor
- University of Twente
CD20+ Aggressive B-Cell Lymphoma
OPTIMAL>60 / DR. CHOP, Improvement of Therapy of Elderly Patients with CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine
The purpose of this study is to improve the outcome of elderly patients with CD20-Aggressive B-Cell Lymphoma and to reduce the toxicity of standard used Immuno-Chemotherapy by using an optimised schedule of the monoclonal…
- Trial name
- OPTIMAL>60 (NCT01478542)
- Testing
- Conventional Vincristine, Liposomal Vincristine, Ricover-scheme rituximab
- Where
- 127 sites in Germany
- Volunteers
- 1,152 people
- Sponsor
- Universität des Saarlandes
Periodontitis, Aggressive, Diode Laser Therapy
Diode Laser With Periodontal Flap Surgery in Periodontitis
The authors theorize that periodontal flap surgery therapy with adjunctive DL therapy might bring favourable therapy results (clinical and bacterial parameters) in patients with stage 3-grade C periodontitis.
- Conditions
- Periodontitis, Aggressive, Diode Laser Therapy, Periodontal Diseases
- Trial name
- NCT05108727
- Testing
- Diode Laser, Modified Widman Flap
- Volunteers
- 18 people
- Sponsor
- Bulent Ecevit University
Substance Use, Deliberate Self-harm
Evaluation of a Brief Surf the Urge Intervention
The purpose of this study is to evaluate the effectiveness of a brief "Surf the Urge" intervention to reduce adolescent and young adult (i.e., 14 to 24 years old) urge-related behaviors.
- Conditions
- Substance Use, Deliberate Self-harm, Trichotillomania, Aggression
- Trial name
- SUBMI (NCT02771886)
- Testing
- Surf the Urge
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kimberly N Schubert
Post Traumatic Stress Disorder, Offensive Aggression
Exploring the Psycho-traumatic Impact of a Violent Act Commited at the Bordeaux-Gradignan Penitentiary Center
The study will seek to explore the possibility of developing post-traumatic stress disorder following a violent offense commited, among the population of prisoners of the Bordeaux-Gradignan penitentiary center.
- Conditions
- Post Traumatic Stress Disorder, Offensive Aggression, Violent Behavior
- Trial name
- IPTAVC (NCT05026450)
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Symptomatic Non-acute Intracranial Artery Occlusion, Ischemic Stroke
Randomized Clinical Trial of Endovascular Recanalization for Symptomatic Non-Acute Intracranial Artery Occlusion（REPAIR）
A multicenter, randomized, open-label, endpoint-blinded trial to compare the effects of endovascular recanalization plus aggressive medical management with aggressive medical management alone on stroke recurrence and mortality in…
- Trial name
- NCT07495969
- Testing
- Endovascular Recanalization Strategy, Aggressive Medical Management
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Feng Gao
Social Competence, Bullying
Effects of ACT OUT! Social Issue Theater on Youth and Adolescents
The ACT OUT! Trial is designed as a proof-of-concept, cluster, randomized, superiority trial with two parallel groups. Although the unit of measurement is student, the unit of randomization is classroom, stratified by school.
- Trial name
- NCT04097496
- Testing
- Act Out! Intervention
- Where
- United States
- Volunteers
- 1,537 people, healthy volunteers welcome
- Sponsor
- Indiana University
Attention Deficit Disorder With Hyperactivity, Conduct Disorder
Medication Strategies for Treating Aggressive Behavior in Youth With Attention Deficit Hyperactivity Disorder
This study will assess whether adding a mood stabilizer, divalproex sodium, to stimulant treatment is more effective than stimulant treatment alone in reducing aggressive behavior among children with attention deficit…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Oppositional Defiant Disorder
- Trial name
- NCT00228046
- Testing
- Divalproex Sodium, Methylphenidate, Dextroamphetamine
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma
A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)
The purpose of this study is to assess the safety and tolerability of zilovertamab vedotin as monotherapy and in combination in participants with select B-cell lymphomas including mantle cell lymphoma (MCL), Richter's…
- Conditions
- Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Follicular Lymphoma, Richter Transformation Lymphoma
- Trial name
- NCT05458297
- Testing
- Zilovertamab vedotin, Nemtabrutinib
- Where
- 109 sites in United States, Brazil and 19 more
- Volunteers
- 189 people
- Sponsor
- Merck Sharp & Dohme LLC
Decision Support Systems, Clinical, Prostate Cancer
Pioneering Advances in Care and Education (PACE)
This clinical trial evaluates the use of novel decision support educational materials and services using health coaches. The study includes men newly diagnosed with low-risk prostate cancer. A 160 men will be recruited.
- Trial name
- PACE (NCT03397160)
- Testing
- Decision Support Intervention (DSI)
- Where
- 4 sites in United States
- Volunteers
- 119 people
- Sponsor
- University of California, San Francisco
Bendamustine, Conditioning Therapy
Bendamustine, Cytarabine, Etoposide and Melphalan (BeEAM) as Conditioning for Autologous Stem Cell Transplant (ASCT) in Aggressive Non Hodgkin's Lymphoma (NHL).
The purpose of this study is to determine whether Bendamustine in combination with Etoposide, Cytarabine and Melphalan (BeEAM) are effective as conditioning followed by ASCT in patients with aggressive lymphoma.
- Conditions
- Bendamustine, Conditioning Therapy, Autologous Stem Cell Transplant, Aggressive Non Hodgkin's Lymphoma
- Trial name
- BeEAM2010-01 (NCT01296256)
- Testing
- Bendamustine-EAM
- Where
- 21 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Aggressive Periodontitis
Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels
The aim of our study is to determine the interleukin-1βeta (IL-1β), interleukin-8 (IL-8) and tumor necrosis factor-αlfa (Tnf-α) levels in gingival crevicular fluid (GCF) and clinical periodontal parameters following the treatment…
- Trial name
- NCT03034824
- Testing
- SRP+940±15 nm diode laser, SRP+Er,Cr:YSGG laser, Scaling and root planing (SRP)-Control
- Volunteers
- 26 people
- Sponsor
- Yuzuncu Yil University
Leukemia, Lymphoma
Multicenter Trial to Treat Patients With Relapsed/Refractory Aggressive Non Hodgkin Lymphoma
This is a multicenter study to assess the anti-tumour activity,to investigate the safety profile and to obtain additional pharmacokinetic information for Aplidin® given as 1-hour weekly IV infusion in patients with aggressive…
- Trial name
- NCT00884286
- Testing
- Aplidin®
- Where
- 12 sites in France, Italy and 4 more
- Volunteers
- 67 people
- Sponsor
- PharmaMar
Lymphoma, Non-Hodgkin
Nivolumab With Gemcitabine, Oxaliplatin + Rituximab in r/r Elderly Lymphoma Patients
This study evaluates the addition of nivolumab to gemcitabine, oxaliplatin plus rituximab in case of B-cell lymphoma
- Trial name
- NIVEAU (NCT03366272)
- Testing
- Nivolumab, Rituximab, Gemcitabine
- Where
- 77 sites in Austria, Belgium and 6 more
- Volunteers
- 348 people
- Sponsor
- Universität des Saarlandes
Bullying
Peer Relationship Program: Effects on Bullying, Peer Relations, Self-Efficacy, and Critical Thinking
This study examines the effects of a Peer Relationship Enhancement Program on early adolescents' attitudes toward bullying, friendships, self-efficacy, and critical thinking skills.
- Trial name
- NCT07206953
- Testing
- Peer Functional Relationship Enhancement Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hilal Mercan Akcay
Arthoplasty
" Comparative Evaluation of Aggressive Gap Arthroplasty With Minimal Gap Arthroplasty in the Management of TMJ Ankylosis "
the most commonly used protocol in the management of TMJ ankylosis is Kabans protocol in which 1.5 to 2 cm aggressive resection of bone is recommended which may lead to gap between cranial base and condyle of mandible.1 However…
- Trial name
- NCT05618795
- Testing
- minimal gap arthoplasty v/s aggressive gap arthoplasty
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak