Clinical trials: Aging, Premature
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
HIV Infection, Vaginal Atrophy
Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial
During menopause, there is a decrease in a hormone estrogen, which leads to aging of the vagina. Vaginal aging includes changes in the type and amount of healthy bacteria in the vagina, inflammation and a breakdown of natural…
- Conditions
- HIV Infection, Vaginal Atrophy, Menopause, Menopause Related Conditions
- Trial name
- NCT04079218
- Testing
- Estradiol Vaginal Insert
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kerry Murphy
Aging, Premature Aging
Dissector Assisted Malar Elevation for Rhytidoplasty
BACKGROUND: Endoscopy was first used in plastic surgery for the treatment of frontal rhytides. This minimally invasive approach allows the treatment of frontal wrinkles using a practical procedure that does not directly interfere…
- Trial name
- DAME (NCT00925158)
- Testing
- Dissector Assisted Malar Elevation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Diminished Ovarian Reserve, Diminished Ovarian Reserve Due to Advanced Maternal Age
Ovarian Function Following Intraovarian Injection of PRP
Consenting women with evidence of poor ovarian reserve will be randomly assigned to treatment with either Platelet Rich Plasma (PRP) or Platelet Poor Plasma (PPP).
- Trial name
- PRP4POA (NCT04278313)
- Testing
- PRP - Platelet Rich Plasma, PPP - Platelet Poor Plasma
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Premature Ovarian Failure
Dehydroepiandrosterone (DHEA) Treatment and Premature Ovarian Failure (POF)
The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with open tubes, fertile male partners and evidence of premature ovarian failure.
- Trial name
- DHEAFert2 (NCT00948857)
- Testing
- Dehydroepiandrosterone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- David H. Barad
HIV-1-infection, Aging, Premature
Mental Ability Challenge Study in Adults With and Without HIV
It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age.
- Conditions
- HIV-1-infection, Aging, Premature, Cognitive Impairment, Memory Impairment
- Trial name
- NCT03244488
- Testing
- Scopolamine Injectable Product, Mecamylamine Pill
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
COPD
Novel Predictors of Premature Aging in COPD Patients
•Examine whether COPD is associated with accelerated aging using a biological marker of aging and dermatological score
- Trial name
- NCT06019286
- Testing
- SCINEXA score
- Volunteers
- 100 people
- Sponsor
- Assiut University
Primary Ovarian Insufficiency, Unexplained Infertility
Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility
The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with otherwise unexplained infertility and evidence of premature ovarian aging (POA).
- Trial name
- DHEAFert (NCT00650754)
- Testing
- Dehydroepiandrosterone
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Telomere Length, Exercise
Physical Exercise in Patients With First Psychotic Episode
Justification: Patients with first-episode psychosis are at increased risk of premature ageing and early mortality, associated with telomere shortening and increased inflammatory markers.
- Conditions
- Telomere Length, Exercise, First Episode Psychosis (FEP)
- Trial name
- NCT07207538
- Testing
- Other: Strength physical exercise programme, Other: Normal life
- Volunteers
- 40 people
- Sponsor
- University of Salamanca
Progeria
Clinical Studies of Progeria
This study will examine children with Hutchinson-Gilford Progeria syndrome, a genetic disease that causes many changes to the body over time, including heart disease, bone changes, hair loss, and joint and skin changes.
- Trial name
- NCT00094393
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Human Genome Research Institute (NHGRI)