Clinical trials: Aging
Ageing
Individual and Environmental Risk Factors of Unplanned Admissions of Elderly
The aim of this multicenter study is to investigate risk factors for unplanned hospitalizations, including individual and environmental factors, notably air pollution.
- Trial name
- RIEHO (NCT00986739)
- Where
- 2 sites in France
- Volunteers
- 973 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pneumonia, Aging
Genomics and Epigenomics of the Elderly Response to Pneumococcal Vaccines
This is a prospective, single-site, randomized, then open-label study designed to develop a detailed transcriptional and epigenetic profile of the immune response to pneumococcal vaccination with conjugated and non-conjugated…
- Trial name
- NCT03104075
- Testing
- Pneumococcal 13valent Conj Vaccine Diphtheria CRM197 Protein, Pneumococcal Vaccine Polyvalent
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Jackson Laboratory
Aging Disorder, Parkinson Disease
Contribution of Virtual Reality and Modelling in Falling Risk Assessment in Elderly and Parkinson's Disease Patients
The process of ageing affects at the same time the sensory, cognitive and driving functions. Furthermore, ageing is often accompanied by pathologies increasing the effects of the senescence.
- Trial name
- PrévSim (NCT03848897)
- Testing
- Metrology of motor behavior
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Aging
Enhancing Cognition in Older Adults With Intermittent Hypoxia and Cognitive Training
The current study will investigate methods for enhancing cognitive training (CT) effects in healthy older adults by employing a combination of interventions facilitating neural plasticity and optimizing readiness for learning.
- Trial name
- EXCITE (NCT03957213)
- Testing
- Acute Intermittent Hypoxia, Computerized Cognitive Training
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Florida
Well Aging
Mindfulness Training for Seniors
The purpose of this research study is to learn more about how mindfulness training may influence thinking and feeling.
- Trial name
- NCT04378803
- Testing
- Mindfulness training (MT) Connect
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Miami
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Insomnia Chronic
Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers
Treatment of insomnia in caregivers is needed given that 60% of Alzheimer disease caregivers report sleep complaints, and insomnia may add to the burden of AD caregiving and contribute to morbidity and mortality risk.
- Trial name
- CARES (NCT03538574)
- Testing
- CBT-I, MAP-I
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of California, Los Angeles
Aging
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise
Advanced age is the main risk factor for chronic diseases such as cardiovascular disease, type 2 diabetes, Alzheimer's disease and cancer.
- Trial name
- NCT03419988
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Healthy Volunteers
Metabolism of Omega-3 and Omega-6 During Healthy Aging
The purpose of this study is to determine the kinetics of 13C-eicosapentaenoic acid (EPA) and 13C-arachidonic acid (AA) in young and older participants
- Trial name
- NCT02957188
- Testing
- 13C eicosapentaenoic acid and 13C arachidonic acid
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Menopause, Gut Microbiome
AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing
AGEWISE is an observational study that aims to understand how changes in gut microbiome are related to hormonal changes during women's ageing, particularly across the different stages of menopause.
- Conditions
- Menopause, Gut Microbiome, Hormonal Changes, Chronic Low-Grade Inflammation
- Trial name
- NCT07614542
- Where
- Portugal
- Volunteers
- 300 people
- Sponsor
- Gulbenkian Institute for Molecular Medicine
Sarcopenia
Sarcopenia, Active Aging and Oral Microbiota. Effects of HIIT in Older Adults
To analyze the effects of a high intensity exercises program by intervals on sarcopenia, active aging and oral microbiota in older adults.
- Trial name
- NCT05220670
- Testing
- HIIT, MICT
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Jaén
Muscle Disuse
Immune Cells During Disuse and Recovery
This is an interventional study enrolling healthy individuals aged 18-35 and 60-85 to understand the recovery of muscle health following a period of inactivity. The enrollment goal is 45 participants.
- Trial name
- NCT04416191
- Testing
- Limb immobilization
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Utah
Aging
Evaluation of Safety and Tolerability of Salvia Haenkei Extract As a Dietary Supplement Ingredient
Evalution of the safety and tolerability of the oral administration of Salvia haenkei in a healthy population.
- Trial name
- NCT05936346
- Testing
- Salvia haenkei 175mg, Salvia haenkei 350mg
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Qualitative Research, Euthanasia
Requests for Euthanasia and Assisted Suicide in Establishment of Accommodation for Dependent Old Persons.
The main aim of this project is to analyze and understand the meaning of explicit requests to hasten death (euthanasia and assisted suicide) from older people living in an Establishment of accommodation for dependent old persons.
- Conditions
- Qualitative Research, Euthanasia, Assisted Suicide, Aging
- Trial name
- DESAGE (NCT03353870)
- Testing
- qualitative interview
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Aging
Impact of Theater Experience on Older Adults Living in Retirement Communities
Theater is a complex, multi-component performing art. On stage, actors not only need to memorize the script, but also be able to portray emotion and feeling through movement and move in whichever manner is deemed appropriate by…
- Trial name
- NCT04582370
- Testing
- theater program
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Joint Pain
Move Study in Healthy Aging People
Bone and muscle losses occur during ageing leading to increased risk of osteoporosis (there are more than 200 million people affected by osteoporosis worldwide), sarcopenia, loss of functionality and mobility.
- Trial name
- NCT02276183
- Testing
- Nutrition intervention, test formula, progressive physical activity
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Aging
Age-related Changes in Ovarian Follicular Wave Dynamics
The investigators hypothesize that age-related changes in the number and growth dynamics of ovarian follicles will be associated with changes in hormone levels and corresponding changes in musculoskeletal health.
- Trial name
- NCT01389141
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Hypertension
Medication Adherence in Hypertension Study
The purpose of this study is to test an intervention to help older adults do a better job of following blood pressure medication regimens prescribed by their health care providers.
- Trial name
- NCT00688350
- Testing
- Behavioral feedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Safety, Peripheral Neuropathy
Xanamem™ in Healthy Elderly Subjects
Xanamem™ is being developed as a potential drug for Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in the body.
- Conditions
- Safety, Peripheral Neuropathy, Cortisol, Central Nervous System
- Trial name
- XanaHES (NCT03830762)
- Testing
- Xanamem
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Aging-related Inflammation in HIV-infected Patients
Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen
Physicians in charge of HIV-infected patients are increasingly being faced to previously unrecognized comorbid conditions such as atherosclerosis and cardiovascular events, loss of renal function, osteopenia/osteoporosis and bone…
- Trial name
- NCT02577042
- Testing
- Raltegravir, PI-based regimen, Atorvastatin
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia