Clinical trials: Aging Frailty
Older People, Frailty
A Technology-based Intervention to Support Older Adults in Living Independently
The general objective of this study is to test the usability and efficiency of the SAVE prototype, a technology-based support for enabling older adults to keep their independent and active lives in their homes and maintain their…
- Trial name
- SAVE (NCT05626556)
- Testing
- SAVE system
- Where
- 3 sites in Hungary, Italy and 1 more
- Volunteers
- 80 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Aging, Frailty
Cognitive-Motor Exergame Training in Frail Adults
This international multicentre pragmatic randomized controlled trial (RCT) aims to evaluate the effectiveness of personalized, home-based cognitive-motor training using exergames in improving cognitive and motor functions in…
- Trial name
- SMART (NCT07074639)
- Testing
- Personalized, home-based motor-cognitive exergame training, Otago Exercise Program
- Where
- Switzerland
- Volunteers
- 344 people
- Sponsor
- Eleftheria Giannouli
Frailty, Sarcopenia
Effect of a Multicomponent Therapeutic Exercise Program in Primary Care on Frailty and Sarcopenia in Older Adults
Background: Frailty and sarcopenia are common conditions in older adults that increase the risk of disability, dependence, and hospitalizations.
- Conditions
- Frailty, Sarcopenia, Aging, Exercises Therapy
- Trial name
- FRACTEP-65 (NCT07132632)
- Testing
- 12-week multicomponent therapeutic exercise program including supervised and home-based sessions focused on strength, balance, mobility, and aerobic capacity
- Volunteers
- 60 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Sarcopenia, Frailty
Evaluation of Efficacy, Tolerability, and Pharmacokinetics of MYMD1 for Chronic Inflammation and Sarcopenia/Frailty
The study will be conducted to investigate the efficacy, tolerability and pharmacokinetics of MYMD1 in participants with chronic inflammation associated with sarcopenia/frailty, a condition linked to elevated levels of…
- Conditions
- Sarcopenia, Frailty, Aging
- Trial name
- NCT05283486
- Testing
- MYMD-1 600MG, MYMD-1 750mg, MYMD-1 900mg
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- TNF Pharmaceuticals, Inc.
Aging, Frailty
Renal Ageing-sarcopenia Network
Frailty is a syndrome in which the accumulation of small, individually insignificant deficits leads to heightened vulnerability to adverse events and predisposes to potential catastrophic decompensation.
- Conditions
- Aging, Frailty, Hypertension, CKD
- Trial name
- NCT04630132
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Healthy Ageing, Frailty
An Intrinsic Capacity Identification and Management Programme for Older Adults in Singapore's Primary Care
The IMPACTFrail program is an intrinsic capacity (IC) identification and management program for mildly frail older adults. Specifically, it delivers the three-tier approach recommended in the National Frailty Strategy Policy…
- Trial name
- IMPACTFrail (NCT06753643)
- Testing
- The IMPACTFrail programme
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Geriatric Education and Research Institute
Aging
Preliminary Testing of Cafe Move for Primary Prevention of Physical Frailty
This project explores a novel means of health promotion and prevention of age-related physical frailty, which is designed to overcome barriers to access and promote autonomy in managing physical health.
- Trial name
- NCT05720507
- Testing
- Cafe Move
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Montana
Dementia
Cardiovascular Risk Factors, Aging and Dementia
The global challenges caused by dementia affect society from both the public health and economic perspective, and are exacerbated by the rapid growth of the population in the oldest age groups.
- Trial name
- CAIDE (NCT03938727)
- Where
- Finland
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Age-related Cognitive Decline, Age-related Physiology Decline
Brain Aging: Muscle-to-brain Axis Modulates Physio-cognitive Decline
The primary goal is to develop a multidomain intervention program focused on preserving global or regional brain volume and functions while simultaneously improving physical mobility and cognitive functions in older individuals…
- Trial name
- NCT05828043
- Testing
- Multi-domain intervention
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- National Yang Ming Chiao Tung University