Clinical trials: Aging Frailty
Healthy Aging, Sarcopenia
Plant-based Diets and Healthy Aging
This prospective study investigates the health effects of vegetarian and plant-based diets in middle-aged and older adults in Taiwan, specifically, recruiting 5000 Tzu Chi volunteers.
- Conditions
- Healthy Aging, Sarcopenia, Frailty, Cognitive Decline
- Trial name
- TCAS (NCT07151365)
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
HIV, Aging
Psychosocial Stress and Aging in HIV
This study will begin to assess the association between perceived stress and enhanced aging in persons living with HIV (PLWH). The investigators suspect this relationship may be mediated by increased aging within the immune…
- Conditions
- HIV, Aging, Stress, Psychological, Frailty
- Trial name
- NCT02965469
- Testing
- Breathe2Relax
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Wake Forest University Health Sciences
Nursing Caries, Old Age; Debility
Multifactorial Study of the Relationship Between the Conditions of Life and the Incidence of Risk of Falling
HYPOTHESIS: The incidence of risk of falls is related to the living conditions of elderly people in the community. OBJECTIVES: To study the relationship between living conditions and the incidence of risk of falls in older adults…
- Conditions
- Nursing Caries, Old Age; Debility, Aging Disorder
- Trial name
- NCT04301713
- Testing
- Evaluation of rik of falls
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Influenza
Systems Investigation of Vaccine Responses in Aging and Frailty
This study will compare the immune response signatures (including immunologic, transcriptomic and metabolomic) of the two influenza vaccines approved for use in adults age 65 and over (Fluad and Fluzone High-Dose).
- Trial name
- NCT05291676
- Testing
- Fluzone, Fluad
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yale University
Aging
Proximity Alarms to Reduce Patient Falls
The purpose of this study is to test an intervention to introduce and implement proximity alarms on the risk of falls in hospitalized patients.
- Trial name
- NCT00183053
- Testing
- BedEx Patient Occupancy Monitoring System
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- National Institute on Aging (NIA)
Aging, Frailty
Evaluation of a Health Monitoring Platform for Elderly in Home Care Context
This study aims at, as a primary objective, studying acceptability of elderly about a health monitoring platform for home support and home care.
- Trial name
- ACCORDS (NCT04514536)
- Testing
- Health monitors
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Aging
Baltimore Longitudinal Study of Aging
Background: The Baltimore Longitudinal Study of Aging (BLSA) is a clinical research program on human aging that began in 1958. Volunteers of different ages join the study when they are healthy, and have follow-up visits for life.
- Trial name
- NCT00233272
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Frailty at Older Adults
Motivational Support for an Autonomous Exercise Program for Healthy Aging
An effective implementation of an exercise programme such as VIVIFRAIL, in an unsupervised mode, requires a careful consideration of the patient's motivational traits and state, and the adaptation of the interventions to the…
- Trial name
- MOTIVA (NCT07447453)
- Testing
- MOTIVA ecosystem
- Where
- 2 sites in Spain
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Veteran Aged 65 and Older
Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy
Frailty is a multifactorial syndrome characterized by vulnerability to stressors that is intricately linked to cognitive impairment and mortality risk.
- Trial name
- Brite-VET (NCT05631236)
- Testing
- Bright Light Therapy (AYO Glasses)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Quality of Life, Syndromes
Long-term Follow-up of the Helsinki Businessmen Study
The Helsinki Businessmen Study (HBS) is a clinico-epidemiological longitudinal study started in 1964. It also included a 5-year randomized, controlled multifactorial primary prevention trial of cardiovascular diseases between…
- Conditions
- Quality of Life, Syndromes, Aging, Cardiovascular Disease
- Trial name
- HBS (NCT02526082)
- Testing
- Intervention
- Volunteers
- 3,490 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Sarcopenia, Frailty
Resistance Exercise Training at Different Intensities
The aim of the current study, therefore, is to determine the feasibility of recruitment and adherence to resistance exercise training interventions performed at low and high loads, to volitional muscular failure, in a trial…
- Conditions
- Sarcopenia, Frailty, Aging
- Trial name
- NCT04053920
- Testing
- Low Load Resistance exercise, High Load Resistance exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
HIV
Feasibility of an Exercise Intervention
The overall purpose of this research is to evaluate the effect of a home-based exercise program on physical function and to improve the health and quality of life for the HIV-infected older adult community.
- Trial name
- MESH (NCT01984060)
- Testing
- HOME-EX
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Rochester
Sarcopenia, Memory Loss
Effects of Multidomain Training of Health With Aging (Train-Old)
The current study aims to determine the effect of a multidomain intervention (physical fitness, motivational and cognitive training) on body composition, sarcopenia, cardiovascular health, physical fitness, functional capacity…
- Conditions
- Sarcopenia, Memory Loss, Muscular Atrophy, Cardiovascular Diseases
- Trial name
- Train-Old (NCT05481346)
- Testing
- Multidomain training
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Preventing Age-Related Muscle Loss: the Role of Exercise in Improving Strength, Function, and Well-being
Muscle Aging Evaluation
This study aims to assess the effects of physical activity in counteracting muscle aging. The increasing life expectancy worldwide has led to a rise in age-related muscle decline, which negatively impacts strength, function, and…
- Trial name
- NCT06845748
- Testing
- Physical activity Group
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Milan
Risk Factors, Complication of Surgical Procedure
ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
- Conditions
- Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia
- Trial name
- ACUTE (NCT05195697)
- Testing
- Observational study of different treatments and time to treatment
- Where
- Sweden
- Volunteers
- 3,000 people
- Sponsor
- Region Skane
Frailty, Frail Elderly Syndrome
Education for Prevention and Treatment of Frailty
Frailty is a condition with a high prevalence in older adults, leading to higher vulnerability and increasing the risk of adverse health outcomes and disabilities.
- Trial name
- FRAGSALUD (NCT05610605)
- Testing
- Health intervention programme: FRAGSALUD
- Where
- Spain
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Fracture, Frailty
The CHARM Study-Coordinating Transitions from Hospital for Older Adults with Fractures
Background: Fall-related injuries like fractures are on the rise among older adults in New Brunswick. These injuries can lead to hospitalization and adverse health effects.
- Conditions
- Fracture, Frailty, Aging
- Trial name
- NCT06107699
- Testing
- Patient Navigation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Horizon Health Network
Sarcopenia
Exercise and Nutrition for Healthy AgeiNg
The aim of this randomized placebo-controlled 5-arm clinical trial is to evaluate the effect of combined anabolic interventions compared to single or placebo interventions on physical performance in community-dwelling…
- Trial name
- ENHANce (NCT03649698)
- Testing
- Home-based training program, High-quality protein supplement, Omega-3 fatty acid
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Obstructive Pulmonary Disease, Heart Failure
Health in Smart Rurality: Impact on Coordination of Care of Telemonitoring and Data Centralization of Frailty Patients
Chronic diseases are frequent (around 10% of the total population and 30% after 60 years) and accelerate age-related functional decline.
- Trial name
- HIS2R (NCT04866550)
- Testing
- Data collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Université de Reims Champagne-Ardenne
Balance Disorders, Accidental Falls
Population Cohort Set-up for the Epidemiological Assessment of Balance Disorders in Elderly People
As people age, it becomes more common to experience balance problems. These issues can increase the risk of falling, which may lead to serious health consequences and loss of independence.
- Conditions
- Balance Disorders, Accidental Falls, Frailty, Aging
- Trial name
- EPIBAS (NCT06965660)
- Where
- Spain
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina