Clinical trials: Aging Well, active
Heart Failure, Atrial Fibrillation
Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study
The STAREE-HEART sub-study will examine the effect of statin treatment over a 3-year period compared with placebo on markers of cardiac ageing (myocardial dysfunction).
- Conditions
- Heart Failure, Atrial Fibrillation, Healthy Ageing, Hypercholesterolemia
- Trial name
- STAREE-HEART (NCT04536870)
- Testing
- Echocardiography, ECG screening
- Where
- 2 sites in Australia
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Monash University
Obesity, Menopause
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
In postmenopausal women, obesity increases the risk of physical function decline, premature aging, and vascular dysfunction. Semaglutide and tirzepatide are potent obesity medications.
- Trial name
- NCT07057310
- Testing
- semaglutide or tirzepatide, Lifestyle modification intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Healthy Aging, Elderly (People Aged 65 or More)
Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals
This research was planned to determine the effect of structured sandplay activities on positive and negative affect and levels of meaning in life in elderly individuals.
- Trial name
- NCT07735351
- Testing
- Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Mild Cognitive Impairment, Healthy Aging
A Novel Computer-Based Functional Skills Assessment and Training Program
People with cognitive impairments such as Mild Cognitive Impairment (MCI), often experience difficulty performing everyday routine activities.
- Trial name
- NCT04679441
- Testing
- The Computerized Functional Skills Assessment and Training Program, Brain HQ Double Decision
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- i-Function, Inc.
Diabetes, Cerebrovascular Disease
Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS)
The Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study is an interdisciplinary, community-based, prospective longitudinal epidemiologic study examining the influences of race and socioeconomic status…
- Conditions
- Diabetes, Cerebrovascular Disease, Age-Associated Decline, Cardiovascular Disease
- Trial name
- NCT01323322
- Where
- United States
- Volunteers
- 3,720 people
- Sponsor
- National Institute on Aging (NIA)
Mild Neurocognitive Disorder, Healthy Aging
tFUS for Memory in mNCD and Healthy Adults
Dementia is an ongoing and growing public health crisis in the US and worldwide. The purpose of this study is to examine a form of noninvasive brain stimulation called transcranial focused ultrasound (tFUS) to the hippocampus…
- Trial name
- NCT06718140
- Testing
- Transcranial Focused Ultrasound
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sleep
Sleep-dependent Learning in Aging
The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both.
- Trial name
- NCT03840083
- Testing
- Sleep
- Where
- United States
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Mild Cognitive Impairment (MCI), Healthy Aging
cMIND AI Web Tool Usability Study (Hong Kong)
This study is testing a new web-based tool that uses artificial intelligence (AI) to help older adults in Hong Kong check how healthy their Cantonese-style meals are for brain health.
- Conditions
- Mild Cognitive Impairment (MCI), Healthy Aging, Nutrition
- Trial name
- NCT07735013
- Testing
- Web-Based AI Dietary Assessment System
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Aging, Supplementation
Aquatic Power Training Dosing Strategies and Creatine Supplementation in Older Adults
This randomized controlled trial will investigate the effects of different aquatic power training dosing strategies and creatine supplementation on functional and multisystem adaptations in community-dwelling older adults.
- Conditions
- Aging, Supplementation, Exercise
- Trial name
- NCT07914270
- Testing
- Time-Based Aquatic Power Training + Creatine, Sedentary Control + Creatine
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Frailty Syndrome, Older Adults, Balance
Effectiveness of Immersive Virtual Reality Combined With Occupational Therapy in Reducing Fall Risk and Frailty Among Older Adults
Population aging is a growing global phenomenon that poses significant challenges to healthcare systems, particularly in preventing falls and managing frailty among older adults.
- Conditions
- Frailty Syndrome, Older Adults, Balance, Fall Prevention in Healthy Aging
- Trial name
- VIRTO-FRAIL (NCT07060677)
- Testing
- Inmersive Virtual Reality, Conventional occupational therapy sessions
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Healthy Aging, Lifestyle-related Condition
Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity
The prevalence of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is mounting worldwide, reaching pandemic proportions.
- Conditions
- Healthy Aging, Lifestyle-related Condition, Metabolic Diseases
- Trial name
- RESTORENAD (NCT06425042)
- Testing
- Nicotinamide Riboside (NR)
- Where
- Chile
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Finis Terrae University
Aging, Cellular Senescence
BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)
Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100.
- Conditions
- Aging, Cellular Senescence, Biomarkers / Blood, Age-Related Diseases
- Trial name
- BIOANCIENT (NCT07707297)
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Fundacion Miguel Servet
Brain Health, Longevity
L-serine and Strength Training in the Elderly
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older…
- Conditions
- Brain Health, Longevity, Cognitive Performance, Strength Training Effects
- Trial name
- AAAging (NCT07466290)
- Testing
- Strength training, L-serine supplementation, Control (cornstarch)
- Where
- Austria
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Institutionalization, Elderly
Aurora: AI-Based Narrative Intervention to Support Emotional Well-Being in Clinical and Non-Clinical Populations
Aurora is an interdisciplinary project evaluating a chatbot-mediated supportive care intervention designed to promote emotional expression, autobiographical meaning-making, identity processes, and emotional well-being through…
- Conditions
- Institutionalization, Elderly, Mental Health, Wellbeing
- Trial name
- Aurora (NCT07494110)
- Testing
- chatbot-mediated supportive care intervention
- Where
- 2 sites in Spain
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Universitat Autonoma de Barcelona
Parkinson's Disease (PD), Healthy Aging
Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease
This study will evaluate whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and in individuals living with Parkinson's disease, populations at high risk of falls and mobility…
- Trial name
- NCT07567482
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre intégré de santé et de services sociaux de l'Outaouais
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
MS-ResearchBiomarkerS
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- MS-ReBS (NCT05204459)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Aging, Health Promotion
Social Prescribing Intervention for Health Promotion in Community-Dwelling Older Adults
This study evaluates the effects of a social prescribing intervention on health promotion outcomes in community-dwelling older adults.
- Conditions
- Aging, Health Promotion, Mental Health
- Trial name
- NCT07540117
- Testing
- Mindfulness Meditation and Walking-Pole Exercise
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Social Isolation in Older Adults, Poverty
Multimodal Training With Immersive Virtual Reality to Improve the Cognitive Health and Emotional Well-being of Older Women Living Alone
This study aims to evaluate the effectiveness of an immersive virtual reality-based multimodal intervention (VirtualDONA) to improve cognitive health and emotional well-being in older women living alone and at risk of poverty.
- Trial name
- VirtualDONA (NCT06956794)
- Testing
- VirtualDONA Multimodal Program
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari de Terrassa
Aging, Aging, Healthy
Emotional Well-being and Measures of Healthy Aging
This randomized control study is designed to understand the role of a positive psychology intervention (PARK: Positive Affect Regulation sKills) in biological aging and well-being.
- Conditions
- Aging, Aging, Healthy, Aging Well, Aging, Biological
- Trial name
- NCT07334106
- Testing
- Positive Emotion Skills Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy Aging
The Role of GABA-mediated Inhibition in Multisensory Temporal Processing & Postural Control in Older Adults
In recent years evidence has accumulated on the association between age-related decline in multisensory temporal processing and postural control.
- Trial name
- NCT03328455
- Testing
- Inhibitory control training, Knowledge-based training
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno