Clinical trials: Agitation, Emergence
Carotid Artery Diseases, Carotid Artery Stenosis
A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction
There are 10.3 million cases of stroke registered in the world every year; 63% of them lead to death. According to World Health Organization, stroke is one of the most important risk factors of death and early disability.
- Trial name
- NCT05126238
- Testing
- Lithium Carbonate
- Where
- Russia
- Volunteers
- 107 people
- Sponsor
- Negovsky Reanimatology Research Institute
Emergence Agitation
Prevention of Emergence Agitation in Rhinoplasty With Subanesthetic Propofol and Single-Dose Dexmedetomidine: A Prospective Double-Blind Clinical Study
To compare of prevention of emergence agitation in rhinoplasty with subanesthetic propofol and single dose dexmedetomidine
- Trial name
- NCT07144007
- Testing
- Dexmedetomidine, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Preoperative Anxiety, Emergence Agitation
Association of Inflammatory Markers With Preoperative Anxiety and Agitation
This study was planned as a prospective, observational study. The study will include pediatric patients aged 3-12 who will undergo surgery.
- Trial name
- NCT06648122
- Testing
- laboratory results
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Agitation, Emergence, Postoperative Delirium
WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane
Inhalation anesthesia is the most frequently used technique and is performed in around 70% of surgeries worldwide. Sevoflurane is the most frequently used halogenated anesthetic and is used in 2/3 of the cases.
- Conditions
- Agitation, Emergence, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- OPERA (NCT04765488)
- Testing
- WashIn /WashOut
- Where
- 3 sites in Russia
- Volunteers
- 200 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Delirium - Postoperative, Agitation
Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery
The goal of this clinical trial is to learn if a novel device (MindfulGarden) is beneficial in a population of patients undergoing cardiac surgery.
- Conditions
- Delirium - Postoperative, Agitation, Anxiety, Cardiac Surgery Recovery
- Trial name
- RESPITE (NCT07051096)
- Testing
- A novel device developed providing nature-driven responsive imagery that responds to the patient's physiological to distract, engage, and de-escalate behaviours of delirium., Routine post-operative management and standard delirium reduction measures.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Cardiac Catheterization, Electrophysiology Procedure
Post Anesthesia Care Unit (PACU) Weighted Blanket Study
This study is being conducted to evaluate the safety and efficacy of weighted blankets to reduce agitation in patients in the post-procedural phase after cardiac catheterization and electrophysiology procedures in the post…
- Conditions
- Cardiac Catheterization, Electrophysiology Procedure, Pediatric Cardiology
- Trial name
- NCT05632640
- Testing
- Standard of Care, Weighted blanket
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Michigan
Magnesium Sulphate, Dexmedetomidine
Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric Patients
This study aimed to compare the effectiveness of intraoperative magnesium sulfate versus dexmedetomidine infusions on emergence agitation that follows anesthesia using sevoflurane immediately and after 30 min in the…
- Conditions
- Magnesium Sulphate, Dexmedetomidine, Emergence Agitation, Pediatric Patients
- Trial name
- NCT06977425
- Testing
- Magnesium sulphate, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Preoperative Anxiety, Emergence Agitation
Effects of Nasal Administration of Dexmedetomidine on Pre-anesthesia Sedation, Intraoperative Brain Electrical Activity, and Incidence of Agitation During Recovery in Children
Pre - operative anxiety and emergence agitation are common issues among pediatric patients, which have various influences on the recovery progress and prognosis of children.
- Trial name
- NCT06896721
- Testing
- Preoperative sedation with dexmedetomidine was administered nasal before surgery, Preoperative sedation with normal saline was administered nasal before surgery
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Fuzhou Hua
Emergence Agitation
The Effect of Oral Gabapentin on Emergence Agitation and Delirium in Adult Patients After Nasal Surgery.
Emergence agitation is a postanesthetic phenomenon that develops in the early phase of recovery from general anesthesia, and is characterized by agitation, disorientation, confusion, and possible violent behavior.
- Trial name
- NCT06887998
- Testing
- Gabapentin 600 mg capsules, Gabapentin 400 mg capsules
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Emergence Agitation, Anesthesia Recovery
Bispectral Index, Suppression Rate and Emergence Agitation in Spine Surgeries
Emergence agitation; generally refers to a situation that may occur after a surgical intervention or anesthesia. This situation describes the irritability and agitation of the patient during the recovery process and the period of…
- Conditions
- Emergence Agitation, Anesthesia Recovery, Bispectral Index Monitor
- Trial name
- NCT06334939
- Testing
- Bispectral Index Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Ahmet Yuksek
Emergence Delirium, Agitation, Emergence
Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy
This is a randomized, prospective, double-blinded (patient and outcome-assessor) trial. Our goal is to assess efficacy of Bridge Therapy (versus sham bridge therapy) to prevent emergence agitation following general anesthesia.
- Trial name
- NCT06387953
- Testing
- Bridge Therapy
- Sponsor
- University of Washington
Postoperative Delirium, Postoperative Agitation
Emergence Agitation in Paediatric Day Care Surgery
Emergence agitation is a significant and persistent challenge in paediatric anaesthesia, especially in children of preschool age.
- Conditions
- Postoperative Delirium, Postoperative Agitation, Anesthesia, Pain Monitoring
- Trial name
- NCT06571890
- Testing
- Narcotrend bispectral index anaesthesia monitor, Mdoloris Anaesthesia Nociception Monitor
- Where
- Denmark
- Volunteers
- 93 people
- Sponsor
- University of Southern Denmark
Agitation, Emergence
Efficacy of Dexmedetomidine vs Midazolam for Early Extubation in Critically Ill Agitated Patients Undergoing Weaning
Comparison of effect of dexmedetomidine and midazolam in icu patients who put on mechanical ventilation and show agitation on weaning.Selection of better agent minimises the drug related side effects like respiratory depression…
- Trial name
- NCT05264077
- Testing
- Dexmedetomidine Hydrochloride
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Hypothermia; Anesthesia, Agitation, Emergence
Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation
The main aim of our study was to investigate the relationship between perioperative hypothermia and postoperative emergence agitation.
- Conditions
- Hypothermia; Anesthesia, Agitation, Emergence, Postoperative Complications, Hypothermia Following Anesthesia
- Trial name
- NCT06543134
- Testing
- surgery, sedation scale
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Emergence Agitation
Efficacy of Remifentanil in Preventing Emergence Agitation
The primary aim of the study was to test the hypothesis that remifentanil administered for analgesia prevents emergence agitation more effectively than fentanyl and N2O in patients undergoing rhinoplasty who received desflurane…
- Trial name
- agitation (NCT06539013)
- Testing
- Remifentanil, N2O, Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Emergence Agitation
Sphenopalatine Ganglion Block for Nasal Surery
nasal surgery carries many perioperative challenges, intraoperative bleeing and its effect on surgical field i the main intraoperative concern an postoperative agitation and its serious complications is the main postoperative…
- Trial name
- NCT04168879
- Testing
- Bupivacaine 0.5% Preservative-Free Injectable Solution, normal saline
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Assiut University
Pain, Agitation, Emergence
Management of PADIS in Emergency Intensive Care Unit
Investigate the prevalence of PADIS in EICU, as well as the awareness and clinical implementation status of medical staff towards PADIS.
- Conditions
- Pain, Agitation, Emergence, Delirium, Critical Illness
- Trial name
- NCT06339385
- Testing
- PADIS assessment
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Capital Medical University
Emergence Agitation
Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
The goal of this clinical trial is to compare Efficacy of low dose propofol(0.5 mg/kg) vs placebo given at the end of sevoflurane anesthesia for prevention of emergence agitation in pediatric patient undergoing MRI scan.
- Trial name
- NCT06218680
- Testing
- Propofol, Normal saline
- Where
- Thailand
- Volunteers
- 134 people
- Sponsor
- Khon Kaen University
Emergence Agitation
Effect of Extubation Under Deep Anesthesia on Emergence Agitation of Nasal Surgery
This study analyzed the relationship between extubation timing and Emergence agitation in 18-60 years old adults undergoing nasal surgery, such as nasal septum correction, endoscopic sinus surgery, and nasal bone fracture…
- Trial name
- NCT04844333
- Testing
- Extubation under deep anesthesia
- Where
- 3 sites in China
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University