Clinical trials: Agitation
Restless Legs Syndrome
Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance
The purpose of this study is to assess the efficacy and safety of pregabalin and pramipexole versus placebo in the treatment of restless legs syndrome and associated sleep disturbance.
- Trial name
- NCT00991276
- Testing
- pregabalin, pramipexole
- Where
- 41 sites in United States
- Volunteers
- 85 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Restless Legs Syndrome, Augmentation
Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist
This is an exploratory, double blinded cross-over study of the D1 antagonist ecopipam treat patients currently having dopamine agonist induced augmentation in restless legs syndrome.
- Trial name
- RLS-Ecopipam (NCT03218969)
- Testing
- Ecopipam
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- William Ondo, MD
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Schizophrenia
Comparison of Intramuscular Olanzapine and Intramuscular Haloperidol in Patients With Schizophrenia
The purpose of this study is to compare intramuscular Olanzapine and intramuscular Haloperidol in changing of agitation in patients with schizophrenia
- Trial name
- NCT00485901
- Testing
- Olanzapine Hydrochloride, Haloperidol
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Eli Lilly and Company
Agitation,Psychomotor
Agitation Follow up After Introduction of a New Patient Care Algorithm
Agitation in the intensive care unit is motor hyperactivity. It is frequent (b/w 30% to 70%) and has multiple causes: pain, medical reason, delirium, medication, etc.
- Trial name
- SARA (NCT04053426)
- Testing
- Implementation of agitation care algorithm
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Grenoble
Restless Legs Syndrome, Multiple Sclerosis
Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms
Study will look at a limited number of participants with various chronic symptoms. Investigating a new and novel form of hypnosis application called "Direct Autonomic Experience (DAX)" which is using combination of visualization…
- Conditions
- Restless Legs Syndrome, Multiple Sclerosis, Trauma, Psychological, Chronic Disease
- Trial name
- HDAX1 (NCT04303143)
- Testing
- Self-Hypnosis, Direct Autonomic Experience Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Inner Group Inc.
Restless Legs Syndrome,, Restless Legs,
Vasculaire Leg Compression Device for the Treatment of Restless Legs Syndrome - A Prospective Clinical Study
Restless legs syndrome (RLS) is a debilitating sleep disorder that has significant impact on quality of life, and often times can be difficult to diagnose and treat effectively.
- Conditions
- Restless Legs Syndrome,, Restless Legs,, Ekbom Syndrome
- Trial name
- NCT01861652
- Testing
- Venous Health Systems Vasculaire Leg Compression Device
- Where
- United States
- Sponsor
- Walter Reed National Military Medical Center
Cesarean Section, Restless Leg Syndrome
Neuraxial Anesthesia and Restless Leg Syndromes in Cesarean
The restless leg syndromes is a common sensorimotor disorder of unknown cause affecting approximately 10% of the population. Different literature had different views on the association between neuraxial anesthesia and the…
- Trial name
- NARELESS (NCT00872248)
- Testing
- Spinal anesthesia, Epidural anesthesia
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Nanjing Medical University
Emergence Agitation, Heart Rate Variability (HRV)
Heart Rate Variability and Anxiety as Predictors of Emergence Agitation After Septorhinoplasty
This prospective observational study aims to evaluate whether preoperative heart rate variability (HRV) and anxiety are associated with, and can help predict, emergence agitation in adult patients undergoing elective…
- Conditions
- Emergence Agitation, Heart Rate Variability (HRV), Septorhinoplasty
- Trial name
- NCT07389135
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya City Hospital
Idiopathic Restless Legs Syndrome
Long Term Study Of Pregabalin In Idiopathic Restless Legs Syndrome Patients
This purpose of this study is to investigate the efficacy and tolerability of pregabalin in treating idiopathic RLS patients for up to 12 months.
- Trial name
- RLS (NCT00806026)
- Testing
- pramipexol, Pregabalin
- Where
- 110 sites in United States, Austria and 7 more
- Volunteers
- 731 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Agitation, Psychosis
Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone
Behavioral and psychological symptoms of dementia (BPSD) are among the most distressing manifestations of dementia. Pharmacotherapy is frequently used and especially in institutional settings.
- Conditions
- Agitation, Psychosis, Alzheimer's Disease
- Trial name
- EscBPSD (NCT01119638)
- Testing
- Escitalopram, Risperidone
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Abarbanel Mental Health Center
Agitation, POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
PARO-agitation-study
Postoperative agitation is a common and serious complication in visceral and transplant surgery, associated with prolonged hospital stays and an increased risk of self-harm.
- Conditions
- Agitation, POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Anxiety After Surgery, Postoperative Pain
- Trial name
- NCT07568093
- Testing
- PARO
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Hannover Medical School
Ear Throat Nose Surgery, Delirium - Postoperative
The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
Delirium is a postoperative complication that hinders a child's recovery and presents challenges in assessment and management. Ear nose throat (ENT) procedures have been suggested as a risk factor for delirium[1].
- Conditions
- Ear Throat Nose Surgery, Delirium - Postoperative, Pain Postoperative
- Trial name
- NCT07191652
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul University - Cerrahpasa
Emergence Agitation
Auricular Acupressure for Reducing Postoperative Emergence Agitation in Preschool Children
This study investigates whether auricular acupressure can reduce postoperative emergence agitation among preschool children following adenoidectomy.
- Trial name
- NCT07472764
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tongren Hospital
Restless Legs Syndrome
Tonic Motor Activation (TOMAC) Therapy in Patients With Restless Legs Syndrome and Dopaminergic Augmentation
This study evaluates Tonic Motor Activation (TOMAC) therapy in adults with restless legs syndrome and dopaminergic augmentation.
- Trial name
- CT-10 (NCT07397247)
- Testing
- Tonic Motor Activation (TOMAC) Device
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Noctrix Health, Inc.
Alzheimer Disease, Agitation
Nabilone for Agitation Blinded Intervention Trial
This study will look at whether nabilone is an effective treatment for agitation in Alzheimer's disease (AD) patients. Agitation is highly prevalent in patients with AD and is one of the most distressing and challenging-to-treat…
- Trial name
- NAB-IT (NCT04516057)
- Testing
- Nabilone
- Where
- 6 sites in Canada
- Volunteers
- 112 people
- Sponsor
- Sunnybrook Health Sciences Centre
Acute Stroke, Psychomotor Agitation
Effect of Virtual Reality on Agitation in Acute Stroke
This randomized controlled, single-blind study evaluates the effect of a Virtual Reality (VR) application on agitation levels and physiological vital signs in patients with acute stroke.
- Trial name
- NCT07787910
- Testing
- Virtual Reality Application, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Alzheimer's Dementia With Behavioral Disturbance
Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related Dementias
The purpose of this study is to investigate the influence of acupuncture on heart rate variability, skin conductance (sweating), and rated behavioral expression of agitation, irritability, and anxiety and mood in qualifying…
- Trial name
- NCT03814382
- Testing
- Acupuncture needle
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Post Tonsillectomy Emergence Agitation
Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric
The goal of this clinical trial is to learn if melatonin can decrease emergence agitation in pediatric post tonsillectomy. The main questions it aims to answer are: Does melatonin decrease emergence agitation in pediatric post…
- Trial name
- NCT07375342
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University