Clinical trials: Air Pollution
Asthma
Effects of Reducing Indoor Air Pollution on the Adult Asthmatic Response
This study is about asthma and how the environment affects asthma. Scientists know that air pollution (such as cigarette smoke and other particles in the air) can make asthma symptoms worse.
- Trial name
- INHALE 2 (NCT02153359)
- Testing
- High Efficiency Particulate Air Cleaner
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Johns Hopkins University
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution
Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB)
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known.
- Trial name
- NCT05087693
- Testing
- Salbutamol, Ozone, Filtered Air
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of British Columbia
Air Pollution
Reducing Traffic Pollution Exposure Improves Blood Pressure
This randomized trial assessed the effect of modifying building envelop and level of air filtration on blood pressure over two hour exposure sessions.
- Trial name
- NCT04029129
- Testing
- Air filtration and building envelop modifications
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- UConn Health
Ozone Exposure During Rest and Exercise
Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function.
- Trial name
- NCT05473000
- Testing
- Exercise, Ozone, Room air
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Air Pollution
Air Pollution Study: The Effect of Ozone on the Lung
The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone.
- Trial name
- NCT02673775
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Environmental Exposure, Nasal Inflammation
Human Biological Responses to Low Level Ozone
To investigate if low level ozone exposure will cause measurable inflammation in nasal cells.
- Trial name
- SNOZ (NCT02857283)
- Testing
- Ozone, Filtered Air, Health and Exposure Tracker (HET)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infant, Low Birth Weight
Household Air Pollution and Health: A Multi-country LPG Intervention Trial
This study is a randomized controlled trial of liquefied petroleum gas (LPG) stove and fuel distribution in 3,200 households in four countries (India, Guatemala, Peru, and Rwanda).
- Trial name
- HAPIN (NCT02944682)
- Testing
- Liquefied petroleum gas (LPG) cookstove
- Where
- 4 sites in Guatemala, India and 2 more
- Volunteers
- 6,704 people
- Sponsor
- Emory University
Attention Impaired, Risk-Taking
Effect of Air Pollution on the Cognitive Function of Adolescents
Previous observational studies have reported an association between higher air pollution exposure and lower attention in children.
- Conditions
- Attention Impaired, Risk-Taking, Risk Behavior, Social Preferences
- Trial name
- ATENC!Ó (NCT03762239)
- Testing
- Purifying the air with a Pure Airbox device (Zonair 3D)
- Where
- Spain
- Volunteers
- 2,123 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Pollution; Exposure, Health Behavior
Improving the Behavioural Impact of Air Quality Alerts
The evidence shows that adherence to air quality advice to adopt protective behaviours during pollution episodes is suboptimal, and that the traditional strategy of simply informing people about high pollution episodes is not…
- Trial name
- NCT03552198
- Testing
- Alternative health advice
- Where
- United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King's College London
Air Pollution Toxicity
Nucleophilic Defense Against PM Toxicity (NEAT Trial)
Carnosine is a naturally occurring peptide found in high levels in skeletal muscle and the brain and is also available commercially as a dietary supplement.
- Trial name
- NEAT (NCT03314987)
- Testing
- L-carnosine
- Where
- United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Cardiovascular Diseases
Cleaner Air for Better Cardiac Biomarkers
This pilot project is a randomized, double-blind, sham-controlled trial investigating whether in-home air pollution reductions using portable air cleaners (PACs) can decrease circulating concentrations of biomarkers of…
- Trial name
- NCT05379400
- Testing
- Portable air cleaner (PAC)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Hypertension
Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention
Using a focused implementation research framework, the EPIS (Exploration, Preparation, Implementation and Sustainment) model in a type-2 hybrid design, the study will be conducted in 3 phases: 1) A pre-implementation phase that…
- Trial name
- NCT05048147
- Testing
- Community Mobilization
- Where
- 4 sites in United States, Nigeria
- Volunteers
- 1,280 people
- Sponsor
- NYU Langone Health
Environmental Exposure
Change in Knowledge After Receiving Personal Air Pollution Results
Personal exposure to air pollution results from the interaction of individual time-activity patterns with levels of air pollution that vary over time and space.
- Trial name
- NCT05160948
- Testing
- Informational Report
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma, Chronic Obstructive Pulmonary Disease
Usability and Acceptability Study of the P-STEP Mobile Application
Assess the usability and acceptance of the P-STEP app, through allowing participants with specific chronic conditions to pilot the app for 12-weeks.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Coronary Heart Disease
- Trial name
- NCT05830318
- Testing
- P-STEP Mobile Application
- Where
- United Kingdom
- Volunteers
- 178 people
- Sponsor
- University of Leicester
Inflammation, Coagulation
Intervention Study on the Health Impact of Air Filters in Chinese Adults
This study aimed to evaluate whether a short-term indoor air purifier intervention improves cardiopulmonary health based on a randomized double-blind crossover trial
- Conditions
- Inflammation, Coagulation, Blood Pressure, Pulmonary Function
- Trial name
- NCT02239744
- Testing
- Air purifiers
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fudan University
Rhinitis, Allergic, Perennial
A Pilot Study In Adults And Adolescents With Irritant (Non-Allergic) Rhinitis
The purpose of this pilot study is to compare the effects (effectiveness and safety)of an intranasal corticosteroid (fluticasone furoate nasal spray [FFNS]) with a placebo nasal spray for the treatment of irritant (non-allergic)…
- Trial name
- NCT00730756
- Testing
- Fluticasone Furoate Nasal Spray
- Where
- 5 sites in Thailand
- Volunteers
- 102 people
- Sponsor
- GlaxoSmithKline
Oxidative Stress, Inflammation
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
This study aims to evaluate whether dietary supplementation with fish oil can protect against the cardiopulmonary alterations linked to air pollution
- Conditions
- Oxidative Stress, Inflammation, Blood Pressure, Vasoconstriction
- Trial name
- NCT03255187
- Testing
- Fish oil supplementation, Sunflower seed oil supplementation
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fudan University