Clinical trials: Air Pollution Exposure
Healthy Individuals, Allergic Rhinitis
Health Effects of Wood Smoke and Traffic-Related Air Pollution Exposures: a Necessary Comparison
Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time.
- Trial name
- WADE (NCT06749093)
- Testing
- Filtered Air (FA), Wood Smoke (WS), Diesel Exhaust (DE)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While short-term breathing problems caused by smoke are well known, there is limited knowledge on how repeated…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Lung Cancer
- Trial name
- LoF (NCT07536178)
- Testing
- Woodsmoke (Lodgepole Pine) exposure, Filtered air exposure
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Disease, Cancer
Biomarkers of Benzene Exposure in Inner City Residents
This study compares air pollution exposures of residents in a South Baltimore community next to major industry with those in a comparison community with much less industry nearby.
- Trial name
- NCT00014963
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pollution; Exposure
Milwaukee Day Cares Indoor Air Quality Assessment and Educational Response Study
This CTSI pilot study will assess for benefit of a community health worker or nursing student taught green cleaning curriculum (developed by the local asthma coalition) provided to Milwaukee County day care staff.
- Trial name
- NCT03675009
- Testing
- Educational Programming
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Heat Strain
Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED-CLIM OW (NCT07634952)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 2 sites in Greece, Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Air Pollution
The Effect of Juice Types on the Responses to Air Pollution
The study hypothesis is that drinking different juices will affect the body's responses to air pollution. Subjects will be exposed to air pollution during a 2-hour car ride on the NJ (New Jersey) Turnpike.
- Trial name
- NCT02027415
- Testing
- Beet juice, Orange juice
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Women Who Gave Birth at Dijon and Besançon CHUs Between 2005 and 2009
Relationship Between Multi-exposure to Noise and Air Pollution and the Onset of Hypertension Disorders During Pregnancy
This retrospective study aimed to analyse the relationship between multi-exposure to noise and air pollution the onset of hypertension disorders during pregnancy It will be conducted in 2650 mothers who gave birth at Dijon or…
- Trial name
- HTA-BQuA (NCT03261245)
- Where
- 2 sites in France
- Volunteers
- 2,650 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Exposure to Polluted Air
Association Between PM2.5 Exposure and Ferroptosis in Seizures Patients
This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway in seizure patients.
- Trial name
- NCT05758129
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Jiangnan University
Focus of Study is to Assess Filter and Stove Use and Efficacy in Reducing Exposure to Waterborne and Airborne Pathogens
Evaluation of a Project to Distribute Water Filters and Cook Stoves in Western Rwanda--Phase 1B
DelAgua Health and Development, Manna Energy and the Rwanda Ministry of Health are collaborating on a project financed by carbon credits that will distribute household-based water filters and high-efficiency cook stoves to…
- Trial name
- NCT01998282
- Where
- Rwanda
- Volunteers
- 1,035 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Exposure to Pollution, Glucocorticoid Resistance
Diesel Exhaust Induces Glucocorticoid Resistance
The investigators are studying the effects of exposure to diesel exhaust on lung inflammation in the presence and absence of an inhaled corticosteroid.
- Trial name
- DIGR (NCT03615742)
- Testing
- Budesonide, Filtered Air, Diesel Exhaust
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
PreDiabetes
Cleaner Air for Lower Cardiometabolic Risk
The purpose of this interventional sham-controlled pilot study is to study the effects of using portable air cleaners (PACs) in outpatient adults with prediabetes.
- Trial name
- NCT05994937
- Testing
- PAC with HEPA filter intact, PAC with HEPA filter removed
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Air Pollution, Pollution; Exposure
Modification of Ambient Air Pollution Exposure and Cardiopulmonary Outcomes by Socioeconomic Status and Nutrition
The goal of this observational study is to compare the effects of air pollution exposure and nutrition between neighborhoods with high and low social vulnerability scores.
- Conditions
- Air Pollution, Pollution; Exposure, Nutrition, Healthy
- Trial name
- SENSE (NCT05843370)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Inflammation
Effects of Dietary Supplements on Response to Air Pollution
This study will determine if a comprehensive antioxidant/anti-inflammatory dietary supplement pack can offer protection against a decline in lung function and increase in inflammation and oxidative stress following acute exposure…
- Trial name
- NCT01488656
- Testing
- Antioxidant, anti-inflammatory dietary supplement
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Utah State University
Pollution; Exposure, Environmental Exposure
The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing
To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors.
- Conditions
- Pollution; Exposure, Environmental Exposure, Childhood Asthma, Childhood
- Trial name
- SynAir-Child (NCT05105386)
- Testing
- SynAir-Child
- Volunteers
- 3,000 people
- Sponsor
- National and Kapodistrian University of Athens
Exposure to Pollution, Heart Failure
Effects of Air Pollution Exposure Reduction by Filter Mask on Heart Failure
Exposure to air pollution is associated with increase in cardiovascular morbidity and mortality. Controlled human exposure studies have demonstrated impaired vascular function and heart rate variability on healthy volunteers.
- Trial name
- NCT01960920
- Testing
- Filtered diesel exhaust, Unfiltered diesel exhaust, Clean air
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute