Clinical trials: Airway
Extubation Failures, Extubation
Comparison of Acute Airway/Respiratory Complications and Intervention Requirements in Extubations Performed During On-Hours Versus Off-Hours
Perioperative airway/respiratory complications are a major driver of morbidity and mortality. While UK audits NAP4 and NAP7 extensively examined major critical events (e.g., cardiac arrest), prospective standardized data on…
- Conditions
- Extubation Failures, Extubation, Airway Complication of Anaesthesia
- Trial name
- NCT07752173
- Testing
- Extubation, Survey/Questionnaire Administration
- Where
- Turkey (Türkiye)
- Volunteers
- 2,640 people
- Sponsor
- Kocaeli City Hospital
Difficult Airway, Intubation, Intratracheal
Correlation Between Bedside Anatomical Indicators and Lifting Force and Glottic Exposure Under Different Video Laryngoscopy Techniques
This single-center prospective observational study plans to enroll 196 patients undergoing elective general anesthesia. The study aims to investigate the correlation between preoperative bedside anatomical indicators (including…
- Trial name
- NCT07846748
- Testing
- Direct Epiglottis Elevation (Subepiglottic Method)
- Volunteers
- 200 people
- Sponsor
- Second Hospital of Shanxi Medical University
Endotracheal Tube Exchange, Airway Management
Bronchoscopic Versus Airway Exchange Catheter-Guided Endotracheal Tube Exchange
This prospective experimental study compares two methods for replacing an endotracheal tube in Thiel-embalmed body donors. The conventional method uses an airway exchange catheter based on the Seldinger technique, whereas the…
- Conditions
- Endotracheal Tube Exchange, Airway Management, Endotracheal Intubation, Reintubation
- Trial name
- Bronchex (NCT07706309)
- Testing
- Airway Exchange Catheter-Guided Endotracheal Tube Exchange, Bronchoscope-Guided Endotracheal Tube Exchange
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Léo Franchetti
Recall, Perceived Applicability
Recall and Perceived Applicability of Ganzouri Airway Scoring System Versus LEMON Score for Airway Assessment Among Anesthesia Residents
Our aim is to compare the recall and perceived clinical applicability of Ganzouri airway scoring system versus LEMON score for airway assessment from residents' perspective.
- Conditions
- Recall, Perceived Applicability, Ganzouri Airway Scoring System, LEMON Score
- Trial name
- NCT07841392
- Testing
- Ganzouri Airway Scoring System, LEMON Score
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Noninvasive Ventilation
The Effects of Nocturnal Non-invasive Ventilation in Stable COPD
Rationale: Application of long-term non-invasive ventilation (NIV) in chronic obstructive pulmonary disease (COPD) patients with chronic hypercapnic respiratory failure (CHRF) has recently been shown to improve outcomes.
- Trial name
- RECAPTURE (NCT03053973)
- Testing
- nocturnal noninvasive ventilation, Standard Care
- Where
- Netherlands
- Volunteers
- 116 people
- Sponsor
- University Medical Center Groningen
Small Airway Dysfunction
Extrafine ICS/LABA Versus As-Needed SABA for Small Airway Dysfunction in Symptomatic Patients With Preserved Spirometry
This study evaluates whether 4 weeks of extrafine inhaled corticosteroid/long-acting β2-agonist (beclomethasone dipropionate/formoterol fumarate, BDP/FOR) therapy improves clinical, physiological, and type 2 inflammatory outcomes…
- Trial name
- NCT07809555
- Testing
- Beclomethasone dipropionate/formoterol fumarate (extrafine), Salbutamol
- Where
- Taiwan
- Volunteers
- 93 people
- Sponsor
- Yi-Han Hsiao
Laryngeal Mask Airway
Effect of Muscle Relaxants on Postoperative Sore Throat in Video Laryngeal Mask Airway(LMA) Use
Video laryngeal masks (VLMAs) are increasingly used as a minimally invasive alternative in airway management. The use of neuromuscular blocking agents can affect VLMA placement and airway physiology.
- Trial name
- NCT07838051
- Testing
- using rocuronium before vide laryngeal mask airway
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Samsun University
Airway Obstruction
Heliox on the Work of Breathing in Adult Patients With Lower Airway Stenosis
Heliox (a mixture of Helium and Oxygen) can reduce the work of breathing in patients with airway stenosis by modifying turbulent flow into laminar flow.
- Trial name
- NCT06457399
- Testing
- Heliox, Oxygen
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Hospital Universitario 12 de Octubre
Obesity & Overweight, Obesity Difficult Airway Airway Management
Predicting Difficult Intubation in Bariatric Surgery: Comparison of El Ganzouri Risk Index and Airway Ultrasound
This study is designed as a prospective observational study and will be conducted at the Health Sciences University Antalya Training and Research Hospital. Adult patients scheduled to undergo bariatric surgery will be included.
- Conditions
- Obesity & Overweight, Obesity Difficult Airway Airway Management, Obesity (Disorder), Difficult Airway
- Trial name
- NCT07316179
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Antalya Training and Research Hospital
Airway Extubation, Extubation Failure
One-Hour Positive Pressure Ventilation After a T-Piece Spontaneous Breathing Trial
This is a randomized, open, multicenter, pragmatic, adaptive clinical trial with intention-to-treat analysis. The study will compare two weaning strategies from mechanical ventilation in critically ill patients admitted to…
- Conditions
- Airway Extubation, Extubation Failure, Weaning Mechanical Ventilation
- Trial name
- GS-Wean Tpiece (NCT07324382)
- Testing
- One-hour positive pressure ventilation, Immediate extubation
- Volunteers
- 4,000 people
- Sponsor
- Hospital do Coracao
Airway Extubation, Weaning Mechanical Ventilation
One-Hour Positive Pressure Ventilation After a Pressure Support Spontaneous Breathing Trial
This is a randomized, open, multicenter, pragmatic, adaptive clinical trial with intention-to-treat analysis. The study will compare two weaning strategies from mechanical ventilation in critically ill patients admitted to…
- Conditions
- Airway Extubation, Weaning Mechanical Ventilation, Extubation Failure
- Trial name
- NCT07324460
- Testing
- One-hour positive pressure ventilation, Immediate extubation
- Volunteers
- 4,000 people
- Sponsor
- Hospital do Coracao
Airway Management, Endotracheal Intubation
REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade Versus Succinylcholine and Rocuronium With Sugammadex for Endotracheal Intubation in Spine Surgery Requiring Motor Evoked Potential Monitoring
The purpose of this research is to compare four commonly used anesthesia medication strategies for placing a breathing tube in patients undergoing spine surgery that requires motor evoked potential (MEP) monitoring.
- Trial name
- REMI-MEP (NCT07835295)
- Testing
- Low-Dose Remifentanil, High-Dose Remifentanil, Succinylcholine
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Mayo Clinic
Tracheal Intubation, Videolaryngoscopy
Video Versus Direct Laryngoscopy for Tracheal Intubation in Pediatric Surgery
Tracheal intubation in paediatric patients is a high-risk procedure in which failure to achieve successful intubation on the first attempt is associated with an increased risk of complications, including hypoxaemia and airway…
- Conditions
- Tracheal Intubation, Videolaryngoscopy, General Anesthesia, Difficult Airway Intubation
- Trial name
- VIDEOKIDS (NCT07495436)
- Testing
- Videolaryngoscope, Direct Laryngoscope
- Where
- Spain
- Volunteers
- 5,562 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Airway Management, Neuromuscular Blockade
Effect of Neuromuscular Blockade on Video Laryngeal Mask Airway Ventilation
This prospective, randomized, double-blind study aims to evaluate the effect of different degrees of neuromuscular blockade on the performance of a video laryngeal mask airway (LMA) during general anesthesia.
- Conditions
- Airway Management, Neuromuscular Blockade, General Anesthesia
- Trial name
- NCT07828977
- Testing
- Normal Saline (Rocuronium 0 mg/kg), Rocuronium 0.3 mg/kg, Rocuronium 0.6 mg/kg
- Volunteers
- 96 people
- Sponsor
- Korea University Guro Hospital
Gastric Ultrasonography, Supraglottic Airways
Comparison of Gastric Volume Changes After Ventilation With Endotracheal Tube, First-Generation Supraglottic Airway, and Second-Generation Supraglottic Airway in Pediatric Patients
This study aims to compare the gastric volumes of pediatric patients undergoing positive-pressure ventilation with different airway management techniques.
- Conditions
- Gastric Ultrasonography, Supraglottic Airways, Supraglottic Airway Use in Children, Gastric Volume
- Trial name
- NCT07555080
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Chronic Cough (CC), Upper Airway Cough Syndrome
Inhaled vs Intranasal Corticosteroids for Chronic Cough in Upper Airway Cough Syndrome
Chronic cough - a cough lasting eight weeks or longer - is one of the most common reasons people see a lung specialist. It can disturb sleep, make conversation difficult, and reduce quality of life.
- Conditions
- Chronic Cough (CC), Upper Airway Cough Syndrome, Chronic Rhinitis
- Trial name
- NCT07777796
- Testing
- Budesonide (400μg/d), Mometasone Furoate 50mcg Nasal Spray
- Where
- Poland
- Volunteers
- 56 people
- Sponsor
- Silesian University of Medicine
Airway Management, Tracheal Intubation
Effect of Night Shift Versus Daytime Duty on Tracheal Intubation Complications and Duration in Surgical Patients
Airway management is one of the most critical steps of anesthesia, and its complications can be life-threatening. Reduced staffing, differences in personnel experience, and physical and mental fatigue during off-hours (evenings…
- Conditions
- Airway Management, Tracheal Intubation, Intubation Complications, General Anesthesia
- Trial name
- NCT07823179
- Testing
- Tracheal Intubation
- Volunteers
- 1,000 people
- Sponsor
- Merve Yazici Kara
Large Airway Collapse, Asthma
A Randomised Feasibility Study of CPAP in Large Airway Collapse
Large airway collapse (LAC) is an increasingly recognised condition characterised by either bowing of the posterior membrane/trachealis muscle into the trachea or main bronchi (also known as excessive dynamic airway collapse…
- Trial name
- RE-LACS (NCT07504926)
- Testing
- CPAP
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Liverpool School of Tropical Medicine
Choking
Evaluation of Foreign Body Airway Obstruction Interventions Among Young Children: A Prospective Cohort Study
Foreign body airway obstruction (FBAO, choking) is a life-threatening emergency requiring time-sensitive treatment to prevent severe injury or deaths.
- Trial name
- NCT07817693
- Where
- Canada
- Volunteers
- 381 people
- Sponsor
- University of Calgary
Choking
Evaluation of Foreign Body Airway Obstruction Interventions: A Prospective Cohort Study of Adults and Children
Foreign body airway obstruction (FBAO, choking) is a life-threatening emergency requiring time-sensitive treatment to prevent severe injury or deaths.
- Trial name
- NCT07814690
- Where
- Canada
- Volunteers
- 640 people
- Sponsor
- University of Calgary