Clinical trials: Airway Anesthesia, active
Airway Edema, Postoperative Complications
Effect of Prophylactic Dexamethasone vs Placebo on Airway Dimensions Assessed by Ultrasonography in Patients Undergoing Laparoscopic Cholecystectomy
During laparoscopic surgery, the abdomen is inflated with carbon dioxide gas (pneumoperitoneum), which alters venous return and fluid distribution, potentially leading to swelling in the tissues of the upper airway.
- Conditions
- Airway Edema, Postoperative Complications, Cholecystolithiasis
- Trial name
- NCT07918495
- Testing
- Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Assiut University
Ultrasonography, Airway Management
Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients
Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues.
- Conditions
- Ultrasonography, Airway Management, Intubation, Intratracheal, Obesity and Overweight
- Trial name
- NCT07346768
- Testing
- None (Observational study)
- Volunteers
- 52 people
- Sponsor
- Gaziantep City Hospital
Anesthesia, Intubation; Difficult or Failed
PrediSuisse: Automatized Assessment of Difficult Airway
In the "PrediSuisse" research project, the investigators aim to create a reliable, reproducible, ultra-portable and radiation-free automatized software, able to identify automatically collected features, facial characteristics…
- Conditions
- Anesthesia, Intubation; Difficult or Failed, Airway Complication of Anesthesia
- Trial name
- PrediSuisse (NCT06453525)
- Testing
- intubation
- Where
- Switzerland
- Volunteers
- 1,800 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Recall, Perceived Applicability
Recall and Perceived Applicability of Ganzouri Airway Scoring System Versus LEMON Score for Airway Assessment Among Anesthesia Residents
Our aim is to compare the recall and perceived clinical applicability of Ganzouri airway scoring system versus LEMON score for airway assessment from residents' perspective.
- Conditions
- Recall, Perceived Applicability, Ganzouri Airway Scoring System, LEMON Score
- Trial name
- NCT07841392
- Testing
- Ganzouri Airway Scoring System, LEMON Score
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Preoxygenation Adequacy Assessed by Oxygen Reserve Index, End-tidal Oxygen and Arterial Blood Gas
"Comparison of Oxygen Reserve Index (ORI), End-Tidal Oxygen, and Time-Based Preoxygenation Targets With Arterial Blood Gas During Preoxygenation
The goal of this observational study is to learn how well different preoxygenation targets reflect the actual amount of oxygen in the blood in adults having planned surgery under general anesthesia.
- Trial name
- NCT07921849
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Anesthesia, Supraglottic Airway Efficiency
Clinical Efficacy Evaluation of Supraglottic Airway Device SafeLM™ in Paediatric Population
The goal of this interventional study is to evaluate the clinical efficacy of SafeLM™, a video laryngeal mask airway device in paediatric population. The main questions it aims to answer are: 1.
- Conditions
- Anesthesia, Supraglottic Airway Efficiency, Paediatric Airway Management
- Trial name
- NCT07266389
- Testing
- SafeLM™ as the airway management device during general anaesthesia
- Where
- 2 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Airway Management, Intubation; Difficult or Failed
Data-driven Development of a Core Dataset for Difficult Airway Alerts
Previous difficult airway management is the most accurate predictor of future difficulty. Consistent documentation is paramount for future airway planning, but requires reliable, reproducible and easily accessible information.
- Conditions
- Airway Management, Intubation; Difficult or Failed, Airway Complication of Anesthesia
- Trial name
- FingAIRprint (NCT07275567)
- Where
- Germany
- Volunteers
- 1,785 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pediatric, Anesthesia Induction
The ED95 of Ciprofol for Laryngeal Mask Airway Insertion With Fentanyl in Children: A Biased-Coin Dose-Finding Trial
Ciprofol is a novel intravenous anesthetic with a pharmacological profile similar to propofol but with a lower incidence of injection pain, hypotension, and respiratory depression.
- Conditions
- Pediatric, Anesthesia Induction, Ciprofol, Laryngeal Mask Airway
- Trial name
- NCT07697404
- Testing
- Ciprofol, Fentanyl
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Huazhong University of Science and Technology
Supraglottic Airway Device
An in Vivo CT Imaging Study of GMA-Tulip, I-gel, and LMA Supreme (GLAM-II)
Laryngeal masks are core devices for supraglottic airway management, and the accuracy of their anatomical position directly impacts ventilation safety and the incidence of complications.
- Trial name
- GLAM-II (NCT07196696)
- Testing
- GMA-Tulip, I-gel, LMA-Supreme insertion
- Where
- 2 sites in China
- Volunteers
- 9 people
- Sponsor
- Zhejiang Cancer Hospital
Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness
Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy
Abstract Objective: The aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed…
- Conditions
- Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness, Airway Complications, Respiratory Complications
- Trial name
- NCT07678086
- Testing
- Pressure Transducer, Traditional Palpation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Airway Management, Anesthesia, General
Comparison of Second- and Third-Generation Laryngeal Mask Airway in Pediatric Patients
This study compares two airway devices used during general anesthesia in children: a second-generation laryngeal mask (SafeLM LMA) and a third-generation video laryngeal mask (SafeLM Video LMA).
- Conditions
- Airway Management, Anesthesia, General, Pediatric Anesthesia
- Trial name
- NCT07912619
- Testing
- Second-Generation SafeLM LMA, Third-Generation SafeLM Video LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Residual Neuromuscular Blockade, Diaphragm Dysfunction
Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
The goal of this prospective observational study is to learn whether diaphragm ultrasound and quantitative neuromuscular monitoring can predict early respiratory events after extubation in adults having elective surgery under…
- Conditions
- Residual Neuromuscular Blockade, Diaphragm Dysfunction, Postoperative Pulmonary Complications, Airway Extubation
- Trial name
- DIAPHEX (NCT07912437)
- Testing
- Diaphragm ultrasonography4
- Volunteers
- 100 people
- Sponsor
- Mustafa Duran
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients
Anesthesiologists commonly administer pain relief during labor or providing anesthesia for cesarean delivery. Two main methods are used to achieve these goal: "Regional anesthesia" where the mother is given medication through a…
- Trial name
- DADB (NCT02193542)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Airway Management
SafeLM Versus LMA Classic for Airway Management During Fibroadenoma Excision
This randomized controlled trial compares the airway management performance of the SafeLM video laryngeal mask with the LMA Classic in adult patients undergoing elective fibroadenoma excision under general anesthesia.
- Trial name
- NCT07835750
- Testing
- SafeLM Video Laryngeal Mask, LMA Classic
- Volunteers
- 132 people
- Sponsor
- Hanoi Medical University
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
Multimodal Opioid-Free Anesthesia in RIRS
The goal of this clinical trial is to evaluate whether a dexmedetomidine-ketamine based opioid-free anesthesia (OFA) protocol can provide effective analgesia compared to conventional fentanyl-based anesthesia in adult patients…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Postoperative Pain
- Trial name
- NCT07636070
- Testing
- Dexmedetomidine-Ketamine Opioid-Free Anesthesia, Fentanyl-Based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- murat sahin
General Anaesthesia Using Supraglotic Airway
A Randomized Controlled SaCo-VLM Trial
A laryngeal mask airway is a medical device placed through the mouth to help patients breathe during general anaesthesia. It is commonly used during surgery.
- Trial name
- NCT07922746
- Testing
- Video-adjusted SaCoVLM insertion, Conventional blind SaCoVLM insertion
- Where
- Malaysia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Airway Management, Learning Curve
Comparison Between the I-gel and Protector Supraglottic Airway Devices
This study aims to compare the learning curves of two different laryngeal mask airway devices, by evaluating their placement in adult patients performed by anesthesiology residents
- Trial name
- NCT06938308
- Testing
- LMA Igel, LMA Protector
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nikolopoulou Maria Zozefin
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Critical Illness, Surgical Procedure, Unspecified
Preoperative Fasting vs. Not Fasting in Critically Ill Patients
The goal of this clinical trial is to learn if fasting or not fasting before a procedure has an effect on recovery in those who are critically ill.
- Conditions
- Critical Illness, Surgical Procedure, Unspecified, Pulmonary Aspiration, Fasting
- Trial name
- FEEDS (NCT06751043)
- Testing
- Fasting, Not fasting
- Where
- 19 sites in United States
- Volunteers
- 1,072 people
- Sponsor
- Massachusetts General Hospital