Clinical trials: Airway Control, open to volunteers
Chronic Obstructive Pulmoriary Disease (COPD), Asthma
Clinical Study on the Treatment of Chronic Airway Diseases (Asthma, Chronic Obstructive Pulmonary Disease) with Shu Fei Tie
Conduct a multi-center, large-sample, randomized controlled clinical study of "winter disease being cared in summer" with Shu Fei Tie prevent recurrence of Asthma and COPD, scientifically evaluate the clinical efficacy and safety…
- Trial name
- NCT06691802
- Testing
- Shu Fei Tie
- Where
- China
- Volunteers
- 2,312 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Respiratory Distress Syndrome in Premature Infant
Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam
Preterm babies often have trouble breathing because their lungs are not fully developed. This condition is called respiratory distress syndrome (RDS). A medicine called surfactant helps their lungs open up and work better.
- Trial name
- NEOSURF (NCT07098910)
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways (SALSA), Intubation - Surfactant administration - Extubation (INSURE)
- Where
- Vietnam
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Airway Management Assessment, Supraglottic Airways
The Insertion of I-gel and Classic LMA in Different Head Positions in Elderly Patients
This prospective, randomized, double-blind clinical study aims to evaluate the insertion success of two supraglottic airway devices, the classic Laryngeal Mask Airway (LMA) and the I-gel, in different head and neck positions in…
- Conditions
- Airway Management Assessment, Supraglottic Airways, Supraglottic Airways for General Anesthesia, Laryngeal Mask Airways
- Trial name
- NCT07027293
- Testing
- STANDART HEAD POSITION, HEAD ROTATION POSITION, Classic laryngeal mask airway (LMA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Airway Management
Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)
This study aims to investigate the optimal oxygen flow rate needed during tracheal intubation with the C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) using Miller-blade or Macintosh-blade size No. 0 or No.
- Trial name
- OPTIMISE-2 (NCT05967507)
- Testing
- Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope, High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope
- Where
- 11 sites in United States, Australia and 5 more
- Volunteers
- 1,192 people
- Sponsor
- Thomas Riva
Obstructive Sleep Apnea, Obesity
UBT251 Injection Phase Ⅲ Study (OSA-NPAP)
The objective of this clinical trial is to evaluate the efficacy of investigational drug UBT251 in the treatment of moderate-to-severe obstructive sleep apnea (OSA) with obesity, as well as to assess its safety.
- Trial name
- UNISHAPE-OSA-1 (NCT07767942)
- Testing
- UBT251
- Volunteers
- 150 people
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Respiratory Distress Syndrome (RDS)
Comparison of Continuous Positive Airway Pressure (CPAP) and Non-Invasive Positive Pressure Ventilation (NIPPV) in Preterm Newborns With Respiratory Distress Syndrome.
Primary objective: to evaluate safety and efficacy of two different non-invasive respiratory support modalities in preterm neonatal patients with respiratory distress syndrome.
- Trial name
- NC3 (NCT06966752)
- Testing
- NIPPV, CPAP
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Vilnius University
Anesthesia Ergonomics, Anesthesia Airway Management
Effect of Anesthesia Equipment Position on Anesthesiologists' Performance
The purpose of this study is to determine if the position of the anesthesia machine affects the ability of anesthesiologists to manage a crisis situation and perform critical tasks.
- Conditions
- Anesthesia Ergonomics, Anesthesia Airway Management, Simulation in Training Center
- Trial name
- NCT07518849
- Testing
- Simualted laryngospasm crisis
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Ventilation During Resuscitation
Intra Arrest Ventilation in Human Cadavers II
The study investigates the influence of three types of ventilation mode by using Bi-Level positive airway pressure (pinsp 20 mbar, PEEP 5, AF 10/min) with two different types of ventilators ( Medumat vs.
- Trial name
- NCT06885398
- Testing
- treatment
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Muehlenkreiskliniken, MKK
Airway Management, Elderly Patients
Effect of New Oropharyngeal Airway on Incidence of Hypoxia During Painless Gastroenteroscopy in Elderly Patients
With the aging of Chinese population, the early screening of gastrointestinal diseases and the promotion and implementation of comfortable medical treatment, more and more elderly patients choose painless gastroenteroscopy for…
- Trial name
- NCT06711328
- Testing
- New oropharyngeal airway
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Supraglottic Airway Devices Position
New-Generation GMA Laryngeal Mask Airway Versus Conventional Inflatable Laryngeal Mask Airway
This study aims to compare the new-generation GMA laryngeal mask airway (LMA) with the traditional inflatable LMA in patients undergoing elective surgery under general anesthesia.
- Trial name
- NCT07177586
- Testing
- GMA Laryngeal Mask Airway, Inflatable Laryngeal Mask Airway
- Where
- China
- Volunteers
- 1,384 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Laryngopharyngeal Reflux
Fosamprenavir for Laryngopharyngeal Upper Airway Tissue Treatment and Enzyme Reduction
Laryngopharyngeal Reflux (LPR) is a common condition that causes symptoms like chronic cough, throat clearing, hoarseness, and trouble swallowing.
- Trial name
- FLUTTER (NCT04383262)
- Testing
- Fosamprenavir Calcium
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Medical College of Wisconsin
Idiopathic Subglottic Stenosis, Subglottic Stenosis (SGS)
Pirfenidone for Idiopathic Subglottic Stenosis: A Pilot Trial of Tolerability and Feasibility
Idiopathic subglottic stenosis (iSGS) is a rare condition where scar tissue forms just below the vocal cords and in the upper windpipe, making the airway narrow.
- Trial name
- NCT07654517
- Testing
- Pirfenidone
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Nontuberculous Mycobacterial Lung Disease, Bronchiectasis
Hypertonic Saline Inhalation for Nontuberculous Mycobacterial Lung Disease
This multicenter randomized controlled trial evaluates the clinical and microbiological effects of inhaled 3% hypertonic saline in treatment-naïve patients with nontuberculous mycobacterial lung disease (NTM-LD).
- Trial name
- HiNTM (NCT07647575)
- Testing
- Nebulized 3% Hypertonic Saline, Nebulized Normal Saline
- Where
- Taiwan
- Volunteers
- 262 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Intratracheal Inbubation
Airway Scope vs GlideScope for Intubation in Obese Patients
This study compares the time required to complete intubation in obese patients (Body Mass Index 40 or greater) when using either the GlideScope or Airway Scope video laryngoscope device to help place the endotracheal tube.
- Trial name
- NCT07453563
- Testing
- Intubation with GlideScope, Intubation with Airway Scope
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of New Mexico
Hypoxia, Airway Obstruction, Postoperative
Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia
The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical…
- Conditions
- Hypoxia, Airway Obstruction, Postoperative, Sore Throat, Cough, Postoperative
- Trial name
- NCT07287293
- Testing
- Routine Endotracheal Suctioning, Omission of Endotracheal Suctioning
- Where
- Thailand
- Volunteers
- 408 people
- Sponsor
- Mahidol University
Airway Management, Tracheal Intubation
Effect of Night Shift Versus Daytime Duty on Tracheal Intubation Complications and Duration in Surgical Patients
Airway management is one of the most critical steps of anesthesia, and its complications can be life-threatening. Reduced staffing, differences in personnel experience, and physical and mental fatigue during off-hours (evenings…
- Conditions
- Airway Management, Tracheal Intubation, Intubation Complications, General Anesthesia
- Trial name
- NCT07823179
- Testing
- Tracheal Intubation
- Volunteers
- 1,000 people
- Sponsor
- Merve Yazici Kara
Obstructive Sleep Apnea
Increasing the Use of an Anti-snoring Mouth Guard (Mandibular Advancement Appliance) to Prevent Upper Airway Collapse During Sleep in Patients With Obstructive Sleep Apnoea.
Obstructive Sleep Apnoea (OSA) is a sleep-related breathing disorder that is characterized by the repeated collapse of the upper airway during sleep, resulting in sleep deprivation.
- Trial name
- IPOSAT (NCT04092660)
- Testing
- Behaviour change Intervention Based on Health Action Process Approach Model, Mandibular Advancement Appliance (MAA) or Anti-snoring mouth guard
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Queen Mary University of London
Asthma
Control and Treatment of Outpatient Children With Asthma
The aim of this study is to comprehensively understand the disease control and management status of children with asthma in China, as well as the types of airway inflammation.
- Trial name
- NCT06837584
- Testing
- Questionnaire and Physical Exam
- Volunteers
- 42,000 people
- Sponsor
- Beijing Children's Hospital
LMA, Pressure Injury
The Influence of Standardized Process Management of Laryngeal Mask Airway Placement Based on Pressure Monitoring on the Incidence of Adverse Reactions in Elderly Patients During the Perioperative Period
The laryngeal mask airway (LMA) is a supraglottic ventilation device designed according to human anatomy. It was developed in 1981 by Dr.
- Conditions
- LMA, Pressure Injury, Elderly, Airway Management
- Trial name
- NCT06954857
- Testing
- Cuff pressure monitor
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Xuanqi Yang
Acute Ischemic Stroke, Stroke-Associated Pneumonia (SAP)
Oropharyngeal Flushing Suction Tube With Laryngoscope for Stroke-Associated Pneumonia
Stroke-associated pneumonia is a common and clinically important complication after acute ischemic stroke, especially in non-intubated patients with impaired consciousness and reduced cough or swallowing reflexes.
- Trial name
- OFST-SAP (NCT07647666)
- Testing
- Oropharyngeal Flushing Suction Tube, Laryngoscope-Guided Oropharyngeal Suction, Standard Suction Catheter
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Pudong New Area Gongli Hospital