Clinical trials: Airway Disease
Respiratory; Complications, Therapy, Bronchiectasis
ELTGOL and Bronchiectasis. Respiratory Therapy
The ELTGOL technique improves mucociliary clearance in adult patients with bronchiectasis. Primary objective: -To evaluate the efficacy of ELTGOL in stable state patients with bronchiectasis compared to placebo.
- Trial name
- ELTGOLBQ (NCT01578681)
- Testing
- Low Expiration Open glottis inferolateral (ELTGOL), Stretching
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Pulmonary Atelectasis, Respiratory Tract Diseases
Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01786681
- Testing
- Positive pressure
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Laryngeal Edema
Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success
This study evaluates laryngeal edema in ICU patients during weaning from mechanical ventilation. It compares the cuff leak test and ultrasound-based laryngeal air column measurements in predicting weaning success.
- Trial name
- NCT07523828
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Asthma
Study to Assess Airway Inflammation Effects of FlutiForm® pMDI Low and High Dose in Adults With Mild to Moderate Asthma
This is a dose-response study to determine how various measurements of airway inflammation respond to high and low dose FlutiForm®, and compared to placebo.
- Trial name
- FLT2503 (NCT00995800)
- Testing
- Fluticasone propionate / Formoterol fumarate
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Mundipharma Research Limited
Respiratory Disease
A Study to Identify Errors in Inhaler Technique in Adults
This study will observe the inhaler technique of people using 13 different inhaler types; record any technique errors being made against checklists developed for each inhaler device based on their manufacturer's guidelines, and…
- Trial name
- SCORES (NCT04262271)
- Where
- United Kingdom
- Volunteers
- 734 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP), Oral Appliance and Physical Exercise in the Obstructive Sleep Apnea
Introduction: It is unclear whether exercise training with or without Continuous Positive Airway Pressure (CPAP) and Oral Appliance (OA) is more effective in reducing symptoms of Obstructive Sleep Apnea (OSA) than treatment…
- Trial name
- NCT01289392
- Testing
- Continuous Positive Airway Pressure (CPAP), Oral Appliance (OA), Physical Exercise
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Thoracic, Diseases
The Effect of Two Airway Interventions, During One Lung Ventilation, on Blood Oxygen Content
Patients requiring one lung ventilation (OLV) for open thoracic surgery will be ventilated (breathing performed by a breathing machine) during anesthesia using a lung protective ventilation strategy (small breath volumes at…
- Trial name
- NCT01495936
- Testing
- RM + Positive End Expiratory Pressure, Continuous Positive Airway Pressure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obstructive Sleep Apnea
Comparison Between Auto CPAP and Fixed CPAP in Chinese Patients With OSA
AutoCPAP would lead to better compliance than FixCPAP
- Trial name
- NCT00307424
- Testing
- AutoCPAP, FixCPAP
- Where
- 2 sites in China
- Sponsor
- Chinese University of Hong Kong
Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
The Impact of Extreme Heat Waves and Air Pollution on the Prognosis of Chronic Airway Diseases
Extreme heat waves (EHW) and air pollution exacerbate chronic airway diseases, but little is known about how these environmental stressors affect quality of life, airway inflammation, symptom control, and pulmonary function.
- Trial name
- NCT07261774
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Respiratory Distress Syndrome
Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants
To evaluate the feasibility, safety and tolerability of aerosolized lucinactant delivered by nasal continuous positive airway pressure (nCPAP) for the prevention of respiratory distress syndrome (RDS) in premature infants.
- Trial name
- NCT00807235
- Testing
- Aerosolized lucinactant
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Windtree Therapeutics
Sleep Apnea, Obstructive, Hypoxia
"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
The purpose of this study is to determine the factors that are associated with improved cardiovascular function with the use of CPAP therapy on subjects diagnosed with moderate to severe obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypoxia, Hypercapnia, Sleep Disorders
- Trial name
- NCT01317329
- Testing
- Clinically prescribed CPAP therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Wisconsin, Madison
Chronic Obstructive Pulmonary Disease, Emphysema
Biological Effects of Quercetin in COPD Phase II
This study determines whether quercetin supplementation reduces the inflammation and oxidative stress markers in patients with chronic obstructive pulmonary disease.
- Conditions
- Chronic Obstructive Pulmonary Disease, Emphysema, Chronic Bronchitis With Airway Obstruction
- Trial name
- polyphenols (NCT06003270)
- Testing
- Quercetin 1000 mg, Quercetin 500 MG
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Temple University
Critical Illness, Respiratory Failure
International Observational Study on Airway Management in Critically Ill Patients
Endotracheal intubation (ETI) is a potentially life-threatening procedure for critically ill patients and major severe complications such as severe hypoxia, cardiovascular collapse and cardiac arrest are common.
- Conditions
- Critical Illness, Respiratory Failure, Hemodynamic Instability, Coma
- Trial name
- INTUBE (NCT03616054)
- Where
- Italy
- Volunteers
- 3,600 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Asthma
Development of Small Airway Disease Questionnaire
The aim of this study is to develop a patient reported outcome tool specific to small airways disease, which assesses symptoms and signs of small airways disease and may help in addition to FEF50% to discriminate between…
- Trial name
- SADQ (NCT01360294)
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- University Medical Center Groningen
Pneumonia
Bubble Continuous Positive Airway Pressure for Children With Severe Pneumonia in Mali, Africa
This study is being conducted in Mali, Africa. Pneumonia is a respiratory infection of the lungs caused by bacteria or virus. Some children can develop signs of severe pneumonia and as a result, have difficulty breathing and low…
- Trial name
- NCT03944551
- Testing
- Bubble CPAP, Standard Therapy
- Where
- Mali
- Volunteers
- 13 people
- Sponsor
- University of Maryland, Baltimore
Obstructive Sleep Apnea
Drug Induced Submental Ultrasound in Obstructive Sleep Apnea Patients
In this study, submental ultrasound during awake and simultaneous under Drug-induced sleep endoscopy is applied in the diagnostic workup of obstructive sleep apnea patients.
- Trial name
- NCT03285451
- Testing
- submental ultrasonography
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Weaning Failure, Mechanical Ventilation
P0.1 and Extubation Failure in Critically Ill Patients
Weaning and extubation are essential steps for the management of critically ill patients when mechanical ventilation (MV) is no longer required.
- Conditions
- Weaning Failure, Mechanical Ventilation, Critically Ill
- Trial name
- NCT05802745
- Testing
- Reintubation
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Cleveland Clinic Abu Dhabi
PreTerm Neonate, nCPAP
The Effect of Massage on Preterm Babies
This study was planned as a randomized controlled experimental study with pre-test post-test design in order to examine the effect of massage on pain, comfort and nutritional status in infants undergoing NCPAP in the NICU…
- Conditions
- PreTerm Neonate, nCPAP, Massage
- Trial name
- NCT06799572
- Testing
- massage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Özlem BOZBUĞA
Reactive Airway Disease, Wheezing
Nasal Findings in Reactive Airway Diseases
Reactive airway diseases is a common respiratory diseases affecting 1-18% of the population in different countries. It carries a significant burden to children, their families, the healthcare system and the overall community.The…
- Trial name
- nasalfinding (NCT03131323)
- Testing
- • Flexible fiberopticnasopharyngoscope
- Volunteers
- 50 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea Syndrome, Gut Microbiota
Intestinal Dysbiosis During Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSA) is one of the most common chronic diseases and is associated with prognostic cardiovascular and metabolic co-morbidities.
- Trial name
- DYNAMIC (NCT04947410)
- Testing
- CPAP or nasal dilators
- Sponsor
- University Hospital, Grenoble
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