Clinical trials: Airway Disease
Septal Deformity, Nasal Obstruction
Clinical Extend Study to Evaluate Safety and Effectiveness of TnR Nasal Mesh for Correction of Nasal Septum on Patients
The purpose of this observation study is to evaluate long term safety and efficacy at 2~3 years after surgery on patients who have completed nasal septal deformity surgery using TnR Nasal Mesh.
- Trial name
- NCT04332575
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.
Cough, Airway Clearance Impairment
Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?
The use of mechanical insufflation-exsufflation (MI-E) in children with neuromuscular diseases (NMD) is recommended by international guidelines and societies and well documented.
- Conditions
- Cough, Airway Clearance Impairment, Neuromuscular Diseases
- Trial name
- MI-Ecoaching (NCT06190431)
- Testing
- Learning the use of an in-exsufflation device with the guidance of a physiotherapist, Using the coaching mode
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Asthma
ICS/LABA Combination With Integrated Dose Counter and Smartphone APP to Improve Asthma Control
Poor adherence to asthma controller medication may link to poor asthma outcome. A metered dose device with built-in dose counter helps physicians to monitor drug compliance in asthma patients.
- Trial name
- NCT02556073
- Testing
- Smartphone action, usual care
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pulmonary Disease, Postoperative Respiratory Complications
Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography
The purpose of this study is to determine whether Electrical Impedance Tomography can be used as sensitive and specific predictor in the detection of postoperative pulmonary complications (e.g.
- Conditions
- Pulmonary Disease, Postoperative Respiratory Complications, Malignant Neoplasm of Stomach, Liver Diseases
- Trial name
- NCT02337673
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Johannes Gutenberg University Mainz
Preterm Infants, Nasal Continuous Positive Airway Pressure
Effect of Therapeutic Touch and Mother's Voice on Pain and Comfort Level During Nasal CPAP Application
Aim: This study was conducted to evaluate the effects of Therapeutic Touch and Mother's Voice on pain and comfort levels of preterm infants during nasal CPAP application.
- Conditions
- Preterm Infants, Nasal Continuous Positive Airway Pressure, Pain Management
- Trial name
- CPAP (NCT05577793)
- Testing
- Mother's Voice, Therapeutic Touch, Mother's Voice +Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Ayşe Belpınar
COPD
Diagnostic and Therapeutic Approaches to Hyperinflation and Small Airway Disease in COPD
Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. Hyperinflation and affection of the small airways are two components that are not represented in current…
- Trial name
- NCT03287921
- Testing
- mono bronchodilatation, dual bronchodilatation
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Universitätsmedizin Mannheim
Disorder Related to Lung Transplantation
Confocal Fluorescence Microscopy of the Human Airways in Diagnostics of Lung Transplantation
Bronchoscopy-guided tissue sampling is a central technique in many diseases including diagnosing and staging lung cancers, diagnosing interstitial lung diseases, and acute and/or chronic rejections following lung transplantation.
- Trial name
- NCT02395393
- Testing
- Alveoflex Confocal MiniprobeTM
- Where
- United States
- Sponsor
- Boston Children's Hospital
Obesity Hypoventilation Syndrome (OHS), Obstructive Sleep Apnea (OSA)
Transdisciplinary Intervention for Obesity Hypoventilation Syndrome
The aims of this prospective observational cohort study are threefold: (1) to assess the prevalence of obesity hypoventilation syndrome (OHS) in individuals with obesity and obstructive sleep apnea (OSA) and identify associated…
- Trial name
- CABS for OHS (NCT07020689)
- Testing
- CABS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Airway Edema, Perioperative Complication
Ultrasound Assessment of Airway Edema During Laparoscopic Cholecystectomy
This prospective, double-blind, randomized clinical trial aims to investigate the development of airway edema associated with intra-abdominal pressure during laparoscopic cholecystectomy.
- Conditions
- Airway Edema, Perioperative Complication, Pneumoperitoneum
- Trial name
- NCT07021482
- Testing
- 10 mmHg Pneumoperitoneum, 14 mmHg Pneumoperitoneum
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Engin Çetin
Obesity, Bariatric Surgery Candidate
Difficult Airway in the Bariatric Patient: The BARINTUBE Cohort Study
Background: Difficult airway in bariatric patients presents significant challenges during anesthesia, impacting patient safety and surgical outcomes.
- Trial name
- BARINTUBE (NCT06592313)
- Testing
- Intubation
- Where
- Mexico
- Volunteers
- 1,290 people
- Sponsor
- : Manuel Alberto Guerrero Gutierrez
COPD
Prospective Exploratory Study to Assess the Effects of the AlphaCore® Device in Patients With COPD
Title: Open-label, prospective exploratory study to assess the effects of the AlphaCore® device on central and peripheral airway dimensions in patients with COPD.
- Trial name
- NCT01720680
- Testing
- Low dose multislice CT thorax, AlphaCore® device
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea
Long-term CPAP Effect with Obstructive Sleep Apnea: a Telemedicine-based
we hypothesize that long-term CPAP could results in increase weight and muscle composite by changing intake content and hormone and the effect was influenced by presence of CVD, social jet lag, and CPAP compliance.
- Trial name
- MSLS-LT (NCT06738940)
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea
Analysis of a New Mask for Positive Airway Pressure (PAP) Device Users
BACKGROUND AND AIMS Continuous positive airway pressure (CPAP) is an effective therapy to treat sleep apnea. Sleep apnea is a condition where the airways collapse when the patient is asleep.
- Trial name
- NCT01847846
- Testing
- CPAP mask - prototype
- Where
- Australia
- Volunteers
- 23 people
- Sponsor
- ResMed
Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia
Relationship Between EIT and Respiratory Status in Very Preterm Infants
Electrical Impedance Tomography (EIT) is a non-invasive imaging technique that can measure lung function in real time. This study will follow premature infants to see if EIT can help predict which infants will be successful in…
- Conditions
- Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
- Trial name
- NCT06609135
- Testing
- Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lawrence Rhein
Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome: Evaluation of the Efficacy of Sleepinnov© (Spiri+) Continuous Positive Airway Pressure Device
Continuous Positive Airway Pressure (CPAP) is the reference treatment of patients suffering from Obstructive Sleep Apnea Syndrome (OSAS).This device functions as a pneumatic stent that stabilizes the upper airway, prevents…
- Trial name
- Spiri+ (NCT04141176)
- Testing
- Spiri+
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Sleepinnov Technology
Resistant Hypertension, Obstructive Sleep Apnea
Effect of Continuous Positive Airway Pressure for Treatment of Obstructive Sleep Apnea on Resistant Hypertension
The objectives of this study are to investigate the effect of continuous positive airway pressure (CPAP) treatment on blood pressure control and vascular inflammation in subjects with resistant hypertension and moderate…
- Trial name
- NCT00881985
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 92 people
- Sponsor
- The University of Hong Kong
Sleep Apnea, Obstructive, Patient Compliance
Continuous Positive Airway Pressure (CPAP) Compliance in Obstructive Sleep Apnea
This study aims to determine the average compliance of a patient under CPAP therapy for obstructive sleep apnea as well as the various factors that influence it.
- Trial name
- CPAPcompl (NCT02301923)
- Where
- Lebanon
- Volunteers
- 450 people
- Sponsor
- Saint-Joseph University
Lung Cancer, Head and Neck Cancer
Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to Gefitinib
We are going to use a special type of bronchoscopy test to examine patients who have had previous surgical treatment for lung cancer or head and neck cancer.
- Trial name
- TIDAL1 (NCT01405846)
- Testing
- Gefitinib
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema
PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
The objective of the present study is to establish the safety and efficacy of multiple administrations of Prochymal™(ex-vivo cultured human adult mesenchymal stem cells) in participants with moderate to severe chronic obstructive…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema, Chronic Bronchitis
- Trial name
- NCT00683722
- Testing
- Prochymal™
- Where
- 6 sites in United States
- Volunteers
- 62 people
- Sponsor
- Mesoblast, Inc.
Sleep Apnea Syndromes, Nasal Obstruction
Randomized Clinical Trial of Nasal Turbinate Reduction to Improve Continuous Positive Airway Pressure (CPAP) Outcomes for Sleep Apnea
Obstructive sleep apnea occurs in 2-4% of middle age adults and results in significant morbidity and mortality. The first line therapy is provision of continuous positive airway pressure (CPAP) via a nasal mask chronically.
- Conditions
- Sleep Apnea Syndromes, Nasal Obstruction, Turbinate Hypertrophy
- Trial name
- TURBO (NCT00503802)
- Testing
- Radiofrequency Turbinate Reduction
- Where
- 3 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Washington
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