Clinical trials: Airway Obstruction
Nasal Congestion and Inflammations
Sonu Nasal Congestion Relief Study in Patients Suffering From Moderate to Severe Nasal Congestion
To demonstrate the safety and effectiveness of Sonu for the treatment of patients suffering from moderate to severe nasal congestion.
- Trial name
- SCORE (NCT05821842)
- Testing
- Sonu
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Third Wave Therapeutics
Nasal Congestion
Market Potential of Carbon Dioxide Nasal Spray
Carbon dioxide (CO2) is a naturally occurring gas that readily diffuses across body tissues and membranes. Data from earlier clinical studies conducted in 975 subjects with allergic rhinitis have shown that nasally administered…
- Trial name
- NCT02113449
- Testing
- Carbon Dioxide
- Where
- 4 sites in United States
- Volunteers
- 147 people
- Sponsor
- GlaxoSmithKline
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Nasal Congestion
Efficacy and Safety of Pediatric Drugs in Nasal Congestion
The purpose of this study is to evaluate the efficacy of the Naridrin in improving nasal congestion.
- Trial name
- NCT02601235
- Testing
- Naridrin, Afrin
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- EMS
Sleep Disorders, Congestion, Nasal
Exploratory Subjective Sleep Study of a Prototype Nasal Dilator
The purpose of this exploratory study is to evaluate the subjective measures of congestion and sleep quality in subjects who suffer from chronic nasal congestion and report trouble with their sleep.
- Trial name
- NCT01122849
- Testing
- Prototype Nasal Dilator, Marketed Nasal Strip
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- GlaxoSmithKline
Asthma
PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction
A study evaluating efficacy and safety of repeated doses of PT027 compared to PT007 in patients with asthma and acute airway obstruction induced by repeated mannitol challenges
- Trial name
- NCT05555290
- Testing
- PT027, PT007
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive, Airflow Obstruction, Chronic
In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency
The Breathe NIOV™ System will reduce the work of breathing in subjects with chronic respiratory insufficiency who require long-term oxygen therapy (LTOT).
- Conditions
- Pulmonary Disease, Chronic Obstructive, Airflow Obstruction, Chronic, Chronic Obstructive Airway Disease, Chronic Obstructive Lung Disease
- Trial name
- NCT01347931
- Testing
- NIOV System, Standard Oxygen Cannula
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Breathe Technologies, Inc.
Nasal Obstruction
Study of the AERin Medical Vivaer® ARC Stylus for Nasal AirWAY Obstruction
Post-market study to continue to evaluate the effectiveness of the Vivaer® ARC Stylus for nasal airway obstruction
- Trial name
- AERWAY (NCT04277507)
- Testing
- Vivaer Stylus
- Where
- 10 sites in United States
- Volunteers
- 122 people
- Sponsor
- Aerin Medical
Dry Nose, Nose Irritation
Pilot Study to Assess Performance and Safety of SULFEX 13081.22 Nasal Spray in Patients With Dry or Irritated Nose
As the medical device is CE marked, the objective of this study is to provide performance and safety data on SULFEX 13081.22 nasal spray as close as possible to the routine care.
- Trial name
- NCT05499078
- Testing
- SULFEX 13081.22
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Church & Dwight Company, Inc.
Nasal Obstruction
The Vivaer Procedure for Treatment of the Septal Swell Bodies (SWELL)
Post-market study to access the clinical use of the Vivaer Arc Stylus to treat Septal Swell Bodies (SSB).
- Trial name
- SWELL (NCT05099263)
- Testing
- Vivaer Arc Stylus
- Where
- 9 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aerin Medical
Nasal Airway Obstruction
A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.
The purpose of this study is to compare the clinical outcomes of the VivAer procedure to functional rhinoplasty and septoplasty surgery for the treatment of nasal airway obstruction (NAO) to establish non-inferiority.
- Trial name
- CompAer (NCT06922955)
- Where
- 35 sites in United States
- Volunteers
- 400 people
- Sponsor
- Aerin Medical
Chronic Obstructive Pulmonary Disease
Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36)
The purpose of this extension study is to evaluate the long-term safety, tolerability, and efficacy of inhaled aclidinium bromide at two dose levels in patients with moderate to severe chronic obstructive pulmonary disease…
- Trial name
- NCT00970268
- Testing
- Aclidinium bromide
- Where
- 83 sites in United States, Canada
- Volunteers
- 291 people
- Sponsor
- AstraZeneca
Airway Obstruction, Sedation Complication
Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022)
The goal of this four-part preclinical [I-II] and clinical [III-IV] trial is to compare, with randomised crossover study design [I-IV], a new medical airway device with standard procedure (biteblock or no device) for upper airway…
- Conditions
- Airway Obstruction, Sedation Complication, Safety Issues, Patient Satisfaction
- Trial name
- NCT05708651
- Testing
- Investigational device [I-IV], Comparator [I-IV]
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stairway Medical AB