Clinical trials: Albumins
Burns
Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two.
The goal of this comparative, interventional randomized controlled trial is to use albumin during resuscitation in pediatric burn patients on day 2, as it can reduce extravasation of fluids and decrease the overall fluid…
- Trial name
- NCT06224777
- Testing
- 5% Albumin (human) Solution, Paeds solution
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- King Edward Medical University
Critical Illness, Fluid Therapy
Intravenous Fluid Practices in Turkish Intensive Care Units (TR-FLUID)
Intravenous (IV) fluids-fluids given directly into a vein-are among the most common treatments used in intensive care units (ICUs).
- Conditions
- Critical Illness, Fluid Therapy, Practices
- Trial name
- NCT07649694
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ondokuz Mayıs University
Refractory Ascites in Patients With Cirrhosis
Refractory Ascitis Diagnosis by the Study of Labelled Albumin Pharmacokinetics
Refractory ascites is an indication for liver transplantation, and includes ascites that is resistant to, or intractable by diuretic therapy (International Ascites Club).
- Trial name
- ARAM (NCT02818673)
- Testing
- labelled human serumalbumin (125-I, Séralb®CisBio), labelled albumin (99m-Tc, Vasculocis®, Cisbio)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Adenocarcinoma
Neoadjuvant Iparomlimab and Tuvonralimab With Nab-P-SOX in Locally Advanced Gastric or Gastroesophageal Junction Cancer
This is a single-center, single-arm, phase 2 clinical study testing a new neoadjuvant (pre-surgery) treatment for patients with locally advanced gastric cancer or gastroesophageal junction (GEJ) cancer.
- Trial name
- NCT07867392
- Testing
- Iparomlimab and Tuvonralimab (QL1706), nab-P-SOX（nab-paclitaxel, oxaliplatin, S-1）
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Ruijin Hospital
Aneurysmal Subarachnoid Hemorrhage
Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages
Aneurysmal subarachnoid hemorrhage (aSAH) is a dreadful acute neurological condition with overwhelmingly high rate of associated morbidities and mortality.
- Trial name
- HASH (NCT06548477)
- Testing
- Human albumin
- Where
- Qatar
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Advanced Pancreatic Cancer
A Study of Docetaxel for Injection (Albumin Bound) in Patients With Advanced Pancreatic Cancer
This study is a randomized, double-blind, multicenter, phase Ⅲ clinical study to compare the clinical efficacy and safety of Docetaxel for Injection (Albumin Bound) in combination with best supportive care versus placebo in…
- Trial name
- NCT06492941
- Testing
- Docetaxel for Injection (Albumin bound), Best supportive care
- Volunteers
- 142 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Lung Cancer, Untreated Stage IV or Recurrent Squamous Cell Lung Cancers
Albumin-Bound Paclitaxel and Gemcitabine in Patients With Untreated Stage IV or Recurrent Squamous Cell Lung Cancers
The purpose of this study is to test the safety and effectiveness of albumin-bound paclitaxel plus gemcitabine in patients with advanced squamous cell lung cancers.
- Trial name
- NCT02525653
- Testing
- albumin-bound paclitaxel, gemcitabine
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Spontaneous Bacterial Peritonitis
Prediction of SBP in Cirrhotic Patients by Platlet Count, Na and AlBl Index.
This study aims to evaluate whether integrating serum sodium levels and platelet count with the Albumin-Bilirubin (ALBI) score can improve the early prediction of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with…
- Trial name
- NCT07116369
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Crp, Insulin Resistance
The Effect of Oral Whey Consumption on Insulin Resistance, Cortisol, Crp, Albumin Level and Healing Quality Before Total Hip Arthroplasty
Purpose: It was planned to determine the effect of oral whey given before total hip arthroplasty (THA) on postoperative insulin resistance, cortisol, CRP((C reactive protein), albumin level and healing quality.
- Conditions
- Crp, Insulin Resistance, Cortisol; Hypersecretion, Albus; Lichen
- Trial name
- WHEY THA (NCT06307782)
- Testing
- whey protein intake before surgery, Water before surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Liver Cirrhosis, Acute Kidney Injury
To Study Efficacy of Albumin in Cirrhosis With Spontaneous Bacterial Peritonitis at Low Risk for AKI Development
The role of Albumin in prevention and Treatment of Acute Kidney Injury (AKI) in patients with Spontaneous Bacterial Peritonitis (SBP) who are at high risk of AKI development has been clearly defined , which decreases the…
- Trial name
- NCT04437810
- Testing
- Albumin, Standard Medical Treatment
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Solid Cancer in a Palliative Situation With Ascites
Serum-Ascites Albumin Gradient Analysis in Cancer Patients in Palliative Care
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites.
- Trial name
- AGASA-SP (NCT03463655)
- Testing
- cirrhotic albumin, serum albumin
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Stroke, Acute Ischemic, Albumin
Intra-arterial Albumin Infusion After Endovascular Therapy for Stroke Patients
The purpose of this study is to investigate the safety and feasibility of intra-arterial albumin infusion for patients with acute ischemic stroke after successful thrombectomy and to further explore the optimal dose of albumin…
- Conditions
- Stroke, Acute Ischemic, Albumin, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- NCT05953623
- Testing
- Albumin
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Tianjin Huanhu Hospital
Diabetes
Association of C-reactive Protein-albumin-lymphocyte Index (CALLY) With All-cause Mortality in Diabetic Patients
Based on retrospective cohort data from 3,988 diabetic patients in the NHANES database, this study is the first to show a significant negative correlation between the CALLY index and all-cause mortality in diabetic patients, with…
- Trial name
- required (NCT06976359)
- Where
- China
- Volunteers
- 3,988 people, healthy volunteers welcome
- Sponsor
- Kunming Children's Hospital
Breast Cancer
Adjuvant Albumin-bound Paclitaxel Versus Taxanes in Breast Cancer: a Real-world Study
This is a prospective, multi-center, real-world study designed to evaluate the efficacy and safety of albumin-bound paclitaxel versus paclitaxel or docetaxel in adjuvant treatment of breast cancer.
- Trial name
- NCT05287308
- Testing
- doxorubicin, epirubicin, pirarubicin
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese Academy of Medical Sciences
Unspecified Adult Solid Tumor, Protocol Specific
Recombinant Albumin Fusion Protein sEphB4-HSA in Treating Patients With Metastatic or Recurrent Solid Tumors
This study is about an experimental drug called sEphB4-HSA (recombinant albumin fusion protein sEphB4-HSA). This research study will be the first time sEphB4-HSA is given to people.
- Trial name
- NCT01642342
- Testing
- laboratory biomarker analysis, pharmacological study, recombinant albumin fusion protein sEphB4-HSA
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Southern California
Transplant-Related Disorder
Albumin, COP and Endothelial Damage in Patients With ESLD Undergoing OLT
To study the correlation between colloid osmotic pressure, albumin and the loss of vascular integrity in terms of endothelial dysfunction in patients with ESLD undergoing OLT and its impact on the perioperative course, as well as…
- Trial name
- NCT03448679
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Preeclampsia, Pulmonary Edema
Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia
The study is planned to describe the prevalence and severity of cardiac, lung and optic-nerve sheath diameter (ONSD) ultrasound abnormalities in women with early onset preeclampsia with severe features.
- Conditions
- Preeclampsia, Pulmonary Edema, Cardiac Function
- Trial name
- NCT05662995
- Testing
- Lung ultrasound
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- University of Cape Town
Advanced Solid Tumors
A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors
This study adopts a multi-center, open-label, non-randomized trial design. It plans to enroll patients with Advanced solid tumor.
- Trial name
- NCT07241936
- Testing
- sirolimus (albumin-bound), DP303c, SYS6043
- Where
- China
- Volunteers
- 444 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Albuminuria
Study of Dietary Additive Phosphorus on Proteinuria and Fibroblast Growth Factor-23
Phosphorus-based food additives are commonly used by food manufacturers for many applications, such as enhancing flavor, in ready-to-eat foods and beverages.
- Trial name
- SODA-POP (NCT02020785)
- Testing
- Higher phosphorus period, Lower phosphorus period
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Geisinger Clinic
Acute Kidney Injury
Influence of Albumin on Acute Renal Dysfunction Associated With Cardiac Surgery Under Extracorporeal Circulation
Acute renal dysfunction associated with cardiac surgery (DRA-ACC) in our hospital population affects 39% of patients, being an important cause of morbidity and mortality, increasing the need for dialysis and assuming a…
- Trial name
- NCT03373318
- Testing
- Human albumin, Plasmalyte
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau