Clinical trials: Alcohol, Drinking
Alcohol Use Disorders
Effectiveness and Costs of Internet-based Treatment for Harmful Alcohol Use and Face-to-face Treatment in Addiction Care
The purpose of this trial is to compare the effectiveness and costs of a five-module Internet-based treatment program (including therapist support) for harmful alcohol use with the effectiveness and cost of the same treatment…
- Trial name
- NCT02671019
- Testing
- Guide to better alcohol habits
- Where
- Sweden
- Volunteers
- 303 people
- Sponsor
- Karolinska Institutet
Alcohol Use
The Less is More Study
In this project, the investigators will implement innovations to extend use of Contingency Management (CM) to facilitate alcohol use reduction among people living with HIV (PLWH).
- Trial name
- NCT05153811
- Testing
- Counseling, mHealth
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Alcohol Consumption
Parent Intervention to Reduce Binge Drinking
Parent and peer interventions to reduce student drinking
- Trial name
- GOALS (NCT01126164)
- Testing
- Parent Handbook and Peer Basics
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Penn State University
Alcohol Dependence
The Self Match Study: A Study of Informed Choice in the Treatment of Addiction
The purpose of this study is to determine whether patient self-matching (as compared with treatment as usual by expert matching) improves quality of life, retention, and outcome for patients being treated for alcohol problems.
- Trial name
- NCT03278821
- Testing
- Self Match, Expert Match
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Kjeld Andersen
Father-Child Relations, Depression
Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya
The goal of this study is to evaluate the feasibility and acceptability of a peer-father counselor delivered psychosocial intervention for fathers at risk for depression and some alcohol use in Eldoret, Kenya in a pilot…
- Conditions
- Father-Child Relations, Depression, Alcohol Use, Unspecified
- Trial name
- NCT06489314
- Testing
- LEAD (Learn, Engage, Act, Dedicate)
- Where
- Kenya
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Florida International University
Alcohol Use Disorder
HLAB-002 of ANS-6637 for Alcohol Use Disorder
Primary: The primary objective of this study was to evaluate the effects of 2 different doses of ANS-6637, 200 mg (given as 2 x 100 mg tablets) and 600 mg (given as 2 x 300 mg tablets) once a day, and matched placebo, on alcohol…
- Trial name
- NCT03970109
- Testing
- ANS-6637
- Where
- 3 sites in United States
- Volunteers
- 43 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Drinking
Investigating the Interactions of AZD0530 With Alcohol in Social Drinkers
The purpose of this alcohol-interaction pilot study is to provide information on the effect of AZD0530 (Saracatinib) on the pharmacokinetics of alcohol and on alcohol responses, including stimulation, sedation, intoxication, body…
- Trial name
- NCT02732587
- Testing
- Saracatinib
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Clinical Outcome of a Patented Pharmaceutical Composition (KT-110) to Treat Alcohol Use Disorder While Avoiding Major Side Effects
Double-blind randomised, parallel-group, three-arm, multicentre, placebo-controlled study The primary objective is to demonstrate the superiority of the combination of Periactine® (cyproheptadine 8 mg/day or 12 mg/day) and…
- Trial name
- COCKTAIL (NCT04108104)
- Testing
- Cyproheptadine, Alpress LP
- Where
- 35 sites in France
- Volunteers
- 154 people
- Sponsor
- Kinnov Therapeutics
Alcohol Dependency
Alcohol Screening, Brief Intervention, and Referral to Treatment in a Military Treatment Facility
An alcohol Screening, Brief Intervention and Referral to Treatment (SBIRT) approach will be adapted for use in a large military hospital setting, and then pilot tested in a military emergency department (ED) to assess its…
- Trial name
- NCT02228967
- Testing
- SBIRT
- Where
- United States
- Volunteers
- 791 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Alcohol Drinking, Depression
Effect of Ethanol and Genetic Polymorphisms on Bupropion Metabolism
The two purposes of this study are 1. to determine what effect the chronic and moderate/heavy drinking of alcoholic beverages has 1.
- Conditions
- Alcohol Drinking, Depression, Smoking Cessation, Attention Deficit Disorder
- Trial name
- NCT00330434
- Testing
- Trial Withdrawn 1, Trial Withdrawn 2
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tufts University
Risk Behavior
Effectiveness of Counseling Interventions to Modify Risk Behaviors in Patients at the Hospital San Ignacio.
Randomized clinical trial that aims to determine the effectiveness of a counseling intervention to modify the stage of behavioral change in risk behaviors (smoking and risky alcohol consumption) in patients candidates for…
- Trial name
- EFICO (NCT03521622)
- Testing
- brief counseling
- Where
- Colombia
- Volunteers
- 440 people
- Sponsor
- Hospital Universitario San Ignacio
Alcohol Use Disorders, Stress Disorders, Posttraumatic
Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers With and Without PTSD
The purpose of the study is to evaluate if the drug prazosin: will decrease alcohol use in active duty members of the military who served in Iraq and/or Afghanistan and determine if presence or absence of posttraumatic stress…
- Conditions
- Alcohol Use Disorders, Stress Disorders, Posttraumatic, Combat Disorders
- Trial name
- NCT02226367
- Testing
- prazosin hydrochloride
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Alcohol Use Disorder (AUD)
Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder
Alcohol use disorder (AUD) is the second highest preventable cause of death in France. Only 3% of patients are prescribed approved drugs for reducing alcohol consumption or maintenance of abstinence.
- Trial name
- MBRP (NCT04598399)
- Testing
- Mindfulness Based Relapse Prevention, Relaxation/ meditation
- Where
- 7 sites in France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Breast Cancer, Smoking Cessation
Brief Intervention for Tobacco and Alcohol Risk Reduction for Couple During Breast Cancer Treatment.
This study will examine the benefits of involving partner in a Screening, Brief Intervention and Referral to Treatment (SBIRT) program for tobacco and alcohol for women treated for breast cancer.
- Conditions
- Breast Cancer, Smoking Cessation, Alcohol Use, Unspecified
- Trial name
- IBMC (NCT04007549)
- Testing
- Brief motivational interview on tobacco/alcohol risk reduction
- Where
- France
- Sponsor
- Institut Bergonié
Alcohol Use Disorder (AUD)
Measuring Beliefs and Norms About Persons With Alcohol Use Disorder
Survey experiment to estimate drivers of stigma toward people with alcohol use disorder
- Trial name
- NCT04832321
- Testing
- Survey questionnaire
- Where
- Uganda
- Volunteers
- 1,363 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alcohol Use Disorder
Phase 1b Study of DCR-AUD in Healthy Volunteers
The goal of this clinical trial is to test the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of of repeat doses of DCR-AUD in adult healthy volunteers who are social drinkers.
- Trial name
- NCT05845398
- Testing
- DCR-AUD
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Alcohol Reactivity
Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
The purpose of this study is the examine the effect of varenicline on cognition to a high dose (0.08 g/dL) of alcohol (vs. placebo alcohol) over the ascending and descending limb of the blood alcohol curve.
- Trial name
- NCT01000987
- Testing
- varenicline
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Alcohol Use Disorder
Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder
BACLOPHONE is a prospective multicenter cohort study, conducted in two nearby French regions (Hauts-de-France and Normandie). BACLOPHONE consists of the monthly phone-based monitoring of 792 patients during their first year of…
- Trial name
- BACLOPHONE (NCT02596763)
- Testing
- Baclofen
- Where
- 19 sites in France
- Volunteers
- 239 people
- Sponsor
- University Hospital, Lille
Binge Drinking, Harmful Use of Alcohol
Efficacy of a Fully Automated Electronic Screening and Brief Intervention to Reduce Harmful Alcohol Consumption: A Randomized Clinical Trial
This epidemiological study (randomized clinical trial) aims to evaluate a digital Screening and Brief Intervention (e-SBI) system for reducing and preventing harmful alcohol consumption in patients treated by the Brazilian…
- Trial name
- PROSA e-SBI (NCT07675447)
- Testing
- screening and brief intervention, electronic screening and brief intervention tool (e-SBI) for reducing rate of harmful alcohol consumption (HAC)
- Where
- Brazil
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Sleep, Alcohol Misuse
Mechanisms of Cannabidiol and Sleep in the Context of Alcohol Use
The goal of this clinical trial is to learn if cannabidiol helps to improve sleep and decrease alcohol use. It will also learn about the safety of cannabidiol.
- Trial name
- CALM (NCT07527338)
- Testing
- Cannabidiol
- Volunteers
- 58 people
- Sponsor
- University of Colorado, Boulder