Clinical trials: Alcohol; Use, Problem; Alcohol Use Disorder
Alcohol Use Disorder, Alcohol Abuse/Dependence
Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder
Glucagon-like peptide-1 receptor agonists (GLP-1RAs), approved for the treatment of type 2 diabetes and obesity, have shown promise as a novel treatment for alcohol use disorder (AUD).
- Conditions
- Alcohol Use Disorder, Alcohol Abuse/Dependence, Alcohol Dependence, Alcoholism
- Trial name
- DUALPSYCHIATRY (NCT06939088)
- Testing
- Tirzepatide
- Where
- 2 sites in Denmark
- Volunteers
- 108 people
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Post Traumatic Stress Disorder (PTSD), Addiction
Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)
This is a randomized controlled Phase II clinical trial designed to evaluate the effects of N-acetylcysteine (NAC) in reducing Alcohol Use Disorder (AUD) severity and Post Traumatic Stress Disorder (PTSD) symptomatology among…
- Conditions
- Post Traumatic Stress Disorder (PTSD), Addiction, Alcohol Abuse
- Trial name
- NCT02966873
- Testing
- N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Functional magnetic resonance imaging (fMRI)
- Where
- 2 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder
Counseling for Alcohol Problems in Pregnancy (CAP-Pre) Phase II
Purpose: This study is testing a new counseling program called Counselling for Alcohol Problems in Pregnancy or CAP-Pre, designed to help pregnant women in South Africa to reduce their alcohol use and improve their well-being.
- Trial name
- CAP-Pre (NCT06853873)
- Testing
- The Counselling for Alcohol Problems in Pregnancy (CAP-Pre) intervention
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH
Alcohol Use Disorder, Alcohol Abuse
Effectiveness of a WeChat-based Alcohol Consumption Intervention Mini-program ("Sober Time ACT") in China
The purpose of this study is to explore whether "Sober Time ACT", a digital intervention tool for alcohol use developed based on wechat mini program, is effective in improving risky alcohol use among Chinese local drinkers.
- Trial name
- NCT05827822
- Testing
- Sober Time ACT
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Abuse, Alcohol Abuse/addiction
A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder
This study will evaluate the safety and exploratory efficacy of AFA-281 in patients with Alcohol use disorder on cravings, subjective response to alcohol, pain thresholds, anxiety, depression, and sleep.
- Conditions
- Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold
- Trial name
- NCT06710431
- Testing
- AFA-281
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Afasci Inc
Alcohol-Related Disorders, Alcohol Use Disorders
Messaging Interventions to Reduce Alcohol Problems Project
The study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in reducing their alcohol consumption.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- MIRAP (NCT03695653)
- Testing
- Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO)
- Where
- United States
- Volunteers
- 730 people
- Sponsor
- Partnership to End Addiction
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma
Alcohol Use Disorder (AUD), Pharmacist-Patient Relations
Alcohol Telemedicine Consultation in Primary Care (ATC)
This pragmatic, cluster-randomized trial in adult primary care clinics in a healthcare system with a diverse membership will examine the effectiveness of an innovative, multi-faceted intervention, the Addiction Telemedicine…
- Conditions
- Alcohol Use Disorder (AUD), Pharmacist-Patient Relations, Alcohol Problem
- Trial name
- ATC (NCT05252221)
- Testing
- ATC Intervention
- Where
- 2 sites in United States
- Volunteers
- 41,843 people
- Sponsor
- Kaiser Permanente
Alcohol Abuse
Deep Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
dTMS intervention to reduce recurrent alcohol abuse among alcohol users who are abstinent for at least 5 days.
- Trial name
- NCT02691390
- Testing
- Active dTMS
- Volunteers
- 51 people
- Sponsor
- Soroka University Medical Center
Depression, Anxiety
The EARN-Health Trial of Financial Savings and Health
The current literature in social epidemiology and public health suggests that low financial savings has an unsurprising negative relationship with subjective well-being, and increases the odds of making visits to a healthcare…
- Conditions
- Depression, Anxiety, Alcohol Abuse, Tobacco Abuse
- Trial name
- EARN-Health (NCT02185612)
- Testing
- Savings program
- Where
- United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alcohol Abuse, Cannabis Abuse
Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse
The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Major Depressive Disorder, Substance-Related Disorders
- Trial name
- NCT00108407
- Testing
- Integrated Cognitive Behavioral Therapy, Twelve Step Facilitation Therapy
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Substance Abuse, Substance Dependence
Group Therapy for Women Prisoners With Comorbid Substance Use and Depression
The purpose of the study is to determine whether interpersonal psychotherapy is effective for treating co-occurring depression and substance use among women prisoners.
- Conditions
- Substance Abuse, Substance Dependence, Depressive Disorder
- Trial name
- NCT00606996
- Testing
- Group interpersonal psychotherapy (IPT-G), Psychoeducation on co-occurring disorders (PSYCHOED)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Brown University
Alcohol Use Disorder, Alcohol Abuse
Talk Therapy by Phone to Promote Treatment for Alcohol Problems
A small percentage of individuals with alcohol use disorder (AUD) obtain alcohol-related care despite research showing that treatment is effective.
- Trial name
- NCT03758274
- Testing
- CBT by Phone to Promote Treatment, Reading the Subject a Pamphlet on Obtaining Alcohol Use Disorder Treatment
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester