Clinical trials: Alcohol Abstinence
Healthy Adult, Alcohol Abstinence
Evaluation of Sodium Excretion and Dietary Intake Via a New Sodium Food Frequency Questionnaire
DETERMINATION OF URINARY SODIUM EXCRETION AND DIETARY SODIUM INTAKE IN ADULTS BY DEVELOPING A FOOD FREQUENCY QUESTIONNAIRE FOR ADDED-SALT FOODS Dear Participant, A doctoral thesis study titled "Determination of Urinary Sodium…
- Conditions
- Healthy Adult, Alcohol Abstinence, Tobacco Abstinence
- Trial name
- NCT07717645
- Testing
- Dietary Assessment (BTS-Salt), Urinary Analysis (Gold Standard vs. Practical), Nutritional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Toros University
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol Use Disorder (AUD)
Medication Development in Alcoholism: Suvorexant Versus Placebo
The primary hypotheses under test are that alcohol dependent subjects treated with suvorexant will report decreased craving for alcohol following alcohol exposure in the laboratory and report significantly less drinking under…
- Trial name
- NCT04229095
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- The Scripps Research Institute
Liver Cirrhosis, Alcoholic
Efficacy of Baclofen in the Treatment of Alcohol Addiction
Intervention to achieve alcohol abstinence represents the most effective treatment for alcoholic patients with liver cirrhosis. However no trials have evaluated the efficacy of anti-craving drugs in these patients because of the…
- Trial name
- NCT00525252
- Testing
- Baclofen
- Volunteers
- 86 people
- Sponsor
- Catholic University of the Sacred Heart
Alcoholism
Integrative Therapy in Alcoholism
The main aim of this project consists in the investigation of the interaction of behavior therapy and Acamprosate in the outpatient treatment of alcoholic patients in a randomized, prospective and (regarding study medication…
- Trial name
- NCT00159107
- Testing
- Acamprosate, Integrative behavior therapy
- Where
- Germany
- Volunteers
- 371 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Alcohol Abuse
Motivational Incentives for Alcohol Abstinence in American Indian and Native Alaskan Adults
This study examines the impact of a culturally tailored version of contingency management treatment on alcohol in 400 alcohol dependent American Indians and Alaskan Natives.
- Trial name
- NCT02174315
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Washington State University
Marijuana Dependence
Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management
Cognitive-behavioral coping skills therapy (CBT) is a widely used and recognized treatment that has been empirically validated for a range of substance use disorders, often with emergent effects and continuing improvement even…
- Trial name
- NCT00350649
- Testing
- Standard CBT, CBT+CM/adherence, CM/abstinence
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Yale University
Alcohol-Related Disorders, Alcohol Use Disorders
Adaptive Interventions for Problem Drinkers
The purpose of this study is to understand how certain interventions help people reduce or quit their drinking and how certain interventions may help best at certain points in time in the change process.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT02511808
- Testing
- Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Northwell Health
Alcohol Use Disorder
Medication Development for Protracted Abstinence in Alcoholism: CORT118335 Versus Placebo
The hypotheses under test are that subjects with alcohol use disorder (AUD) of moderate or greater severity treated with CORT118335 will report decreased craving for alcohol following alcohol exposure in the laboratory and report…
- Trial name
- NCT04466215
- Testing
- Miricorilant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Scripps Research Institute
Alcohol Drinking, Alcohol Use Disorder
Alkontrol-herbal Effects on Alcohol Drinking
Participants will enroll in a 14-week study (2 weeks of baseline, 8 weeks of treatment, and 4 weeks of follow-up) investigating the impact that Alkontrol-herbal (Isoflavone; Kudzu) has on alcohol intake in a population seeking…
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Abstinence
- Trial name
- Alkontrol (NCT03099590)
- Testing
- kudzu extract, puerarin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Mclean Hospital
Alcohol Use
Remote Monitoring and Contingency Management Reinforcement for Alcohol Abstinence
This pilot project proposes to monitor real-world alcohol use using a novel technology-cell phone videorecordings in conjunction with breathalyzer recordings-and to conduct a small randomized study of this technology for…
- Trial name
- NCT01307345
- Testing
- contingency management for abstinence
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- UConn Health
Alcohol Withdrawal
Liver Stiffness Measurement in Alcohol-dependent Subjects in Relation to Abstinence After Withdrawal
This study is complementary to the main study "Brain Derived Neurotrophic Factor Serum Levels Evolution During the Six Months After Alcohol Withdrawal " NCT01491347.
- Trial name
- NCT02202148
- Where
- France
- Volunteers
- 195 people
- Sponsor
- Centre Hospitalier Esquirol
Alcohol Dependence
The Efficacy of A Smartphone-based Support System to Reinforce Alcohol Abstinence in Treatment-seeking Patients
Background: Interactive and mobile technology to manage alcohol use problem potentially provide continuing care by offering emotional and instrumental support anywhere and in time, but the effectiveness for maintaining abstinence…
- Trial name
- NCT02385643
- Testing
- SmartPhone Support System
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Ming-Chyi Huang
Alcohol Dependence
Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence
The purpose of this study was to assess efficacy and safety of the study drug Odelepran, 125 mg as compared to placebo in the treatment of alcohol dependence in adult outpatients.
- Trial name
- NCT03663374
- Testing
- Odelepan
- Where
- 22 sites in Kazakhstan, Russia
- Volunteers
- 644 people
- Sponsor
- R-Pharm
Smoking Cessation, Alcohol Drinking
Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking
Alcohol misuse and smoking constitute two of the three leading preventable causes of death in the United States. The purpose of this research study is to develop an intervention designed to help people stop drinking alcohol and…
- Trial name
- NCT02995915
- Testing
- Nicotine Replacement Therapy, Bupropion, Cognitive Behavioral Treatment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Alcohol Abuse, Posttraumatic Stress Disorder
Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder
The purpose of this study is to determine whether the drug prazosin is effective for the treatment of alcohol dependency and symptoms of Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01518972
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Opioid-use Disorder, Neonatal Abstinence Syndrome
MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study
This is a multi-center prospective comparative cohort study examining the safety, efficacy, pharmacokinetics, and pharmacogenomics of naltrexone for pregnant women with opioid use disorder.
- Conditions
- Opioid-use Disorder, Neonatal Abstinence Syndrome, Pregnancy, High Risk, Alcohol Use Disorder
- Trial name
- NCT03718104
- Testing
- Pharmacokinetic analysis, Safety and Efficacy, Genetic and epigenetic analysis
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Boston Medical Center
Alcohol Use Disorder
Anxiety During Abstinence in AUD
The goal of this study is to better understand the underlying neurobiological basis of anxiety that emerges during abstinence in patients with alcohol use disorder (AUD). The main questions it aims to answer are: 1.
- Trial name
- NCT06793488
- Testing
- Disulfiram 250 mg, functional MRI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Alcohol Abstinence
The Use of Telephone-based ACT for Quitting Alcohol in the Young Population With Hazardous or Harmful Alcohol Use.
Objectives: To investigate the effectiveness of a telephone-based acceptance and commitment therapy (ACT) in assisting young adult drinkers with hazardous or harmful alcohol use (HH drinkers) to quit drinking.
- Trial name
- NCT07450248
- Testing
- Telephone-based ACT, Telephone-based social support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University