Clinical trials: Alcohol Abuse/Dependence
Stress Disorders, Post-Traumatic, Alcohol Abuse
Combined Treatment for Alcohol-Dependent Individuals With PTSD
This treatment intervention trial is designed for men and women with either alcohol misuse (e.g. hazardous or binge drinking) or alcohol use disorders (alcohol abuse or dependence) and comorbid PTSD.
- Conditions
- Stress Disorders, Post-Traumatic, Alcohol Abuse, Substance-Related Disorders
- Trial name
- NCT00262223
- Testing
- Seeking Safety, Sertraline
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- New York State Psychiatric Institute
Schizophrenia, Mood Disorders
Alcohol Use Disorders in Schizophrenia
The purpose of the study is to evaluate a new treatment to help patients who have problems because of their use of alcohol. The treatment is called Behavioral Treatment for Alcohol Abuse in Schizophrenia (BTAAS).We are interested…
- Conditions
- Schizophrenia, Mood Disorders, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT00280813
- Testing
- Supportive Treatment in Addiction Recovery (STAR)
- Where
- 4 sites in United States
- Volunteers
- 54 people
- Sponsor
- University of Maryland, Baltimore
Alcohol Dependence
Mindfulness Meditation for Health
The purpose of this 52-week clinical trial is to see if the meditation-based intervention, adjunctive to standard of care therapy, can reduce relapse and improve psychological health among adults recovering from alcohol…
- Trial name
- NCT01056484
- Testing
- Mindfulness Based Relapse Prevention for Alcohol Dependence, "Wait-list" control
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Wisconsin, Madison
Alcohol Dependence
Citicoline for Alcohol Dependence
The purpose of this study is to determine if citicoline, as an add-on therapy, will help reduce alcohol use in outpatients with alcohol dependence.
- Trial name
- NCT02074735
- Testing
- Citicoline
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Texas Southwestern Medical Center
Alcohol, Drinking
Michigan SPARC Trial
Unhealthy alcohol use is a major contributor to morbidity and mortality in the US. Although effective prevention for unhealthy alcohol use and medication treatment for alcohol use disorders (AUDs) can be provided in primary care…
- Conditions
- Alcohol, Drinking, Alcohol Use Disorder (AUD)
- Trial name
- MI-SPARC (NCT04861792)
- Testing
- Michigan SPARC Quality Improvement Intervention
- Where
- United States
- Volunteers
- 9,590 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Domestic Violence, Substance Abuse
Treatment of Intimate Partner Violence and Substance Abuse in a Substance Abuse Treatment Facility
Intimate partner violence is a significant societal problem. There is considerable evidence that a strong relationship between the use of alcohol and other drugs and intimate partner violence exists.
- Trial name
- NCT00847873
- Testing
- substance abuse/domestic violence treatment, Cognitive behavioral therapy addressing substance abuse
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- VU University of Amsterdam
Alcohol Abuse, Cannabis Abuse
Trial of Computerized SBI to Reduce Teen Alcohol Use
The goal of this project is to test the effectiveness of a computer-facilitated alcohol screening and brief intervention (c-ASBI) system for 12- to 18-year-old primary care patients in a multi-site, randomized comparative…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Nicotine Dependence
- Trial name
- NCT01784627
- Testing
- c-ASBI
- Where
- 6 sites in United States
- Sponsor
- Boston Children's Hospital
Alcohol Dependence, Alcohol Abuse
Sweet Preference and Alcohol Craving
Purpose: The proposed 2-year investigation will be the first double-blind, placebo-controlled trial examining the hedonic response to sweet taste (HRST) as a phenotypic predictor of naltrexone (NTX) response in alcohol…
- Trial name
- SweetNal (NCT01296646)
- Testing
- Naltrexone, Brenda Therapy Sessions
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Abuse, Alcoholism
Consequences of At-risk Alcohol Consumption in ICU Patients
At-risk drinking is known to cause a high incidence of alcohol withdrawal syndrome which has a high impact on morbidity and mortality.
- Trial name
- NCT03565016
- Testing
- no interventional study
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Bipolar Disorder, Alcohol Abuse/Dependence
Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
The abuse of alcohol is especially common in people with bipolar disorder. However, very little is known about the pharmacotherapy of people with both bipolar disorder and alcohol abuse/dependence.
- Trial name
- NCT00223249
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Anger
Clinical Trial With Ziprasidone for the Treatment of Psychiatric Pathology Associated to Alcoholism
Alcohol dependent patients show comorbid psychiatric symptoms, related to malfunction of dopamine, norepinephrine and serotonin neurotransmission, during early recovery.
- Conditions
- Depression, Anger, Anxiety, Alcoholism
- Trial name
- NCT00197951
- Testing
- Treatment of psychiatric symptoms associated to alcoholism
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Post Traumatic Stress Disorder, Alcohol Use Disorder
Zonisamide Outpatient Study
The objective of this study is to determine if, compared to placebo, zonisamide (400mg/day) is a safe and efficacious treatment for post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) in Veterans with PTSD and…
- Trial name
- NCT03376139
- Testing
- Zonisamide
- Where
- United States
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Binge Drinking, Alcohol Abuse
Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans
This study will determine whether a cognitive behavioral intervention that demonstrates strong evidence in the U.S. of reducing alcohol use is effective when delivered by paraprofessionals in Kenya and compared against a usual…
- Conditions
- Binge Drinking, Alcohol Abuse, Alcohol Dependence, HIV Infections
- Trial name
- KHBS (NCT00792519)
- Testing
- HIV support group, CBT
- Where
- Kenya
- Volunteers
- 75 people
- Sponsor
- Brown University
Alcohol Dependence
Combination of Naltrexone and Baclofen for Alcohol Dependence:A Pilot Study.
The purpose of this research study is to learn about the use of a combination of two medications, baclofen and naltrexone, for the treatment of alcohol dependence in men and women ages 25-60 years old.
- Trial name
- NCT00614328
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Dependence, Alcohol Abuse
Carisbamate as a Potential Treatment for Alcohol Dependence
The purpose of this study is to determine the effects of treatment with carisbamate compared to treatment with placebo, on alcohol-induced stimulant and subjective effects in non-treatment seeking alcohol-dependent human…
- Conditions
- Alcohol Dependence, Alcohol Abuse, Substance Abuse
- Trial name
- NCT02435381
- Testing
- Carisbamate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Baylor College of Medicine
Depression, Alcoholism
Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism
We will study patients with a current major depressive episode, comorbid alcoholism and a history of a past suicide attempt. All subjects with alcohol dependence will be evaluated for risk of alcohol withdrawal prior to…
- Conditions
- Depression, Alcoholism, Suicidal Behavior
- Trial name
- NCT00449007
- Testing
- fluoxetine, bupropion
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- New York State Psychiatric Institute
Alcoholism
Alcohol and Women : Screening in General
The alcohol consumption of adults has been decreasing in France since the sixties. When focusing on the particular case of women, this trend goes on the opposite direction.
- Trial name
- NCT04647565
- Testing
- interviews
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Alcohol Dependence
Does Varenicline Influence Alcohol Consumption in Alcohol Dependent Individuals?
The aim of the present clinical trial is to investigate whether 14 weeks of treatment with a prescription medication for smoking cessation (European trade name: Champix(R); US trade name: Chantix(R)), can reduce alcohol…
- Trial name
- NCT00846859
- Testing
- varenicline (Champix/Chantix)
- Where
- 3 sites in Sweden
- Volunteers
- 162 people
- Sponsor
- Sahlgrenska University Hospital
Alcohol Abuse, Alcohol Drinking
TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda
The investigators will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcoholism, Alcohol Use Disorder
- Trial name
- TREAT C-AUD (NCT04743024)
- Where
- Uganda
- Volunteers
- 7,188 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma