Clinical trials: Alcohol Abuse/Dependence
Alcoholism
Varenicline for Alcohol Dependence
The primary objective of this study is to assess the efficacy of varenicline in reducing the proportion of heavy drinking days during the last 8 weeks of treatment in subjects with alcohol dependence confirmed by Diagnostic and…
- Trial name
- NCIG 003 (NCT01146613)
- Testing
- Varenicline
- Where
- 7 sites in United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Social Anxiety Disorder, Social Phobia
Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism
The purpose of the study is to determine whether an SSRI, paroxetine, improves social anxiety symptoms and alcohol use in individuals who drink to cope with social anxiety disorder.
- Conditions
- Social Anxiety Disorder, Social Phobia, Alcohol Use Disorder, Alcohol Abuse
- Trial name
- NCT00246441
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Medical University of South Carolina
Alcohol, Drinking, Alcohol Use Disorder
Sustaining Patient-centered Alcohol-related Care
Alcohol use is the third greatest cause of disability and death for US adults. Care for unhealthy alcohol use is lacking in most primary care settings.
- Trial name
- SPARC (NCT02675777)
- Testing
- Quality Improvement Intervention
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Abuse
Smartphone Based Continuing Care for Alcohol
Investigators will recruit 280 alcohol dependent patients in treatment programs in the Philadelphia area to test the efficacy and cost efficiency of a smartphone based application for treating alcohol addiction (ACHESS) with…
- Trial name
- NCT02681406
- Testing
- ACHESS, TMC
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- University of Pennsylvania
Bipolar Disorder, Alcoholism
Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder
The purpose of this study is determine whether the use of topiramate is effective in the treatment of alcohol dependence (i.e. decreases drinking) in patients with bipolar disorder.
- Conditions
- Bipolar Disorder, Alcoholism, Alcohol Dependence
- Trial name
- NCT00572117
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Alcoholism, Alcohol Abuse
Zonisamide vs. Placebo in the Treatment of Alcohol Dependence
This is a pilot study designed to examine the potential efficacy and tolerability of zonisamide compared to placebo for the treatment of alcohol dependence.
- Conditions
- Alcoholism, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT00595556
- Testing
- zonisamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UConn Health
Cocaine Dependence, Alcohol Dependence
VIVITROL as a Treatment for Cocaine and Alcohol Dependence
To evaluate the efficacy of VIVITROL (naltrexone for extended-release injectable suspension) for the treatment of co-occurring cocaine and alcohol dependence
- Trial name
- NCT00777062
- Testing
- VIVITROL (Naltrexone extended-release injectable suspension)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania
Alcohol Dependence, Alcoholism
Topiramate for Alcohol Use in Posttraumatic Stress Disorder
Alcohol abuse and dependence (alcohol use disorders, AUDs) and posttraumatic stress disorder (PTSD) are both prevalent in Veterans.
- Conditions
- Alcohol Dependence, Alcoholism, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- NCT01408641
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
Alcohol-Related Disorders, Alcoholism
Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence
Modafinil is a medication that may enhance mood and increase energy in cocaine addicts, which may be useful in preventing cocaine relapse. Naltrexone is a medication that is currently used to treat drug and alcohol addiction.
- Conditions
- Alcohol-Related Disorders, Alcoholism, Cocaine-Related Disorders
- Trial name
- Mod-Nal (NCT00142818)
- Testing
- Naltrexone, Modafinil
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Kyle Kampman