Clinical trials: Alcohol Abuse/Dependence
Alcohol Abuse or Dependence, Alcohol Use Disorder
Examination of Whether an Exercise Programme Reduces Alcohol Consumption Among Alcohol-Dependent Adults
This study is composed of two phases. Phase 1 will determine baseline demographic characteristics of participants, currently drinking harmful amounts of alcohol, who would be interested in an alternative treatment option to…
- Trial name
- AOA (NCT03848000)
- Testing
- Exercise Programme, NHS Standard Care
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- Queen Mary University of London
Alcohol, Drinking, Alcohol Use Disorder
Sustaining Patient-centered Alcohol-related Care
Alcohol use is the third greatest cause of disability and death for US adults. Care for unhealthy alcohol use is lacking in most primary care settings.
- Trial name
- SPARC (NCT02675777)
- Testing
- Quality Improvement Intervention
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Abuse
Smartphone Based Continuing Care for Alcohol
Investigators will recruit 280 alcohol dependent patients in treatment programs in the Philadelphia area to test the efficacy and cost efficiency of a smartphone based application for treating alcohol addiction (ACHESS) with…
- Trial name
- NCT02681406
- Testing
- ACHESS, TMC
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- University of Pennsylvania
Substance Abuse, Substance Dependence
fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults
The purpose of this study is to determine whether drug-dependent adults who participate in a dual processing relapse prevention treatment protocol that allows for sensory-based exposure experiences over 10-weeks in outpatient…
- Conditions
- Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use
- Trial name
- NCT01320748
- Testing
- Dual Processing, Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Inova Health Care Services
Bipolar Disorder, Alcoholism
Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder
The purpose of this study is determine whether the use of topiramate is effective in the treatment of alcohol dependence (i.e. decreases drinking) in patients with bipolar disorder.
- Conditions
- Bipolar Disorder, Alcoholism, Alcohol Dependence
- Trial name
- NCT00572117
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Alcoholism, Alcohol Abuse
Zonisamide vs. Placebo in the Treatment of Alcohol Dependence
This is a pilot study designed to examine the potential efficacy and tolerability of zonisamide compared to placebo for the treatment of alcohol dependence.
- Conditions
- Alcoholism, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT00595556
- Testing
- zonisamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UConn Health
Problem Drinking, Alcohol Dependence
Screening and Brief Intervention in the ED Among Mexican-origin Young Adults
The aims of this study are to: 1) examine the effectiveness of Screening, Brief Intervention and Referral to Treatment (SBIRT) among Mexican-origin young adults (age 18-25), using a motivational intervention delivered by a Health…
- Trial name
- NCT02056535
- Testing
- Brief Motivational Intervention
- Where
- United States
- Volunteers
- 698 people
- Sponsor
- Public Health Institute, California
AOD Use, Abuse, and Dependence, Depression
Treatment for Teens With Alcohol Abuse and Depression
The investigators will recruit adolescents with alcohol or cannabis abuse and clinically significant depression. All participants will receive 12 sessions of an evidence-based treatment for alcohol abuse, Motivation Enhancement…
- Trial name
- T-TAAD (NCT02227589)
- Testing
- MET/CBT-12, CBT-D, D-TAU
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Duke University
Alcohol Use Disorder, Alcohol Dependence
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
This study will collect data that measures the effects of a psychedelic intervention on patients struggling with alcohol use disorder (AUD).
- Conditions
- Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
- Trial name
- Psi or Ket (NCT06405607)
- Testing
- Psilocybin, Ketamine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Iowa
Drug Addiction, Stimulant Dependence
CRAFT Behavior Therapy: Treatment Entry Component
This research compares the benefits of the original treatment, Community Reinforcement and Family Training (CRAFT), with the Treatment Entry Training (TEnT) component of CRAFT to determine if TEnt alone can produce the primary…
- Conditions
- Drug Addiction, Stimulant Dependence, Opiate Dependence, Alcohol Dependence
- Trial name
- NCT00842036
- Testing
- Community Reinforcement and Family Training, Treatment Entry Training, 12- step Al/Nar- Anon Facilitation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Treatment Research Institute
Alcoholism, Gambling
Effectiveness of Sertraline in Treating Pathological Gamblers With a Diagnosis of Alcohol Dependence - 1
Pathological gamblers often are also dependent on alcohol and clinically depressed. Sertraline (Zoloft) is currently used to treat depression, panic disorder, and obsessive-compulsive disorder.
- Trial name
- NCT00249431
- Testing
- Sertraline, Relapse Prevention Therapy
- Volunteers
- 9 people
- Sponsor
- New York State Psychiatric Institute
Alcohol Dependence, Alcohol Abuse
A Smartphone Based Intervention for the Prevention of Relapse in Alcohol Dependence
The rate of relapse following an inpatient alcohol rehabilitation program has been around 50% for a number of years. Offered treatments mainly focus on conscious and controllable aspects of behaviour, but research has found that…
- Conditions
- Alcohol Dependence, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- SPIRA (NCT03952429)
- Testing
- Anti Alcohol App with Active Cognitive Bias, Inactive Cognitive Bias Modification
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Salus Klinik Lindow
Alcohol Dependence
Helping Problem Drinkers on the Internet
The main aim of this study is to compare the impact of a minimal and a full Internet-based self-help intervention for problem drinkers in the general population.
- Trial name
- NCT01114919
- Testing
- Check Your Drinking (CYD), Alcohol Help Centre (AHC)
- Where
- Canada
- Volunteers
- 246 people
- Sponsor
- Centre for Addiction and Mental Health
Alcohol Use Disorder, Substance Use Disorders
Evaluating a One-Year Version of the Parent-Child Assistance Program
The proposed project seeks to achieve three objectives that will, collectively, evaluate the effectiveness of a one-year version of the Parent-Child Assistance Program (PCAP-1) -a model for a home visitation and case management…
- Conditions
- Alcohol Use Disorder, Substance Use Disorders, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use Disorders
- Trial name
- PCAP-1 (NCT06163651)
- Testing
- Parent-Child Assistance Program - One-Year Version
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Oklahoma
Alcohol Abuse, Alcohol Dependence
The iHealth Study in College Students
The objective of this project was to test the feasibility of electronic mail recruitment and web screening for hazardous drinking, to compare different approaches to encouraging screening, and to estimate the effects of minimal…
- Conditions
- Alcohol Abuse, Alcohol Dependence, Unhealthy Alcohol Use, Risky Alcohol Consumption Amounts
- Trial name
- NCT00183131
- Testing
- Brief Personalized Feedback
- Where
- United States
- Volunteers
- 4,300 people
- Sponsor
- Boston Medical Center
Cocaine Dependence, Alcohol Dependence
VIVITROL as a Treatment for Cocaine and Alcohol Dependence
To evaluate the efficacy of VIVITROL (naltrexone for extended-release injectable suspension) for the treatment of co-occurring cocaine and alcohol dependence
- Trial name
- NCT00777062
- Testing
- VIVITROL (Naltrexone extended-release injectable suspension)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania
Alcohol Abuse/Dependence, Alcohol Use Disorder (AUD)
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder
The goal of this clinical trial is to learn about the effects of the combination of ketamine and realtime functional magnetic resonance imaging (fMRI) neurofeedback training on the treatment of individuals with alcohol use…
- Conditions
- Alcohol Abuse/Dependence, Alcohol Use Disorder (AUD), Alcoholism
- Trial name
- Nektar (NCT06969937)
- Testing
- Ketamine, Real-time fMRI Neurofeedback Training
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Dr. med. Marcus Herdener
Alcohol Abuse, Alcohol Dependence
Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons
This research is designed to assess if problem drinking by treatment seeking individuals can be treated (reduced) by kudzu extract pharmacotherapy plus medical management therapy.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Heavy Drinking Days
- Trial name
- NCT01853293
- Testing
- Kudzu extract, Medical Management
- Where
- United States
- Sponsor
- Mclean Hospital
Use; Tobacco, Harmful, Alcohol Abuse
Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
The purpose of the project is to improve adolescent behavioral counseling services in healthcare settings with a new Internet/Intranet-based Motivational Enhancement Therapy (iMET) intervention that targets the use of tobacco…
- Conditions
- Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
- Trial name
- NCT00907309
- Testing
- iMET, iMET/TE
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Boston Children's Hospital
Alcohol Dependence
Aripiprazole and Topiramate on Free-Choice Alcohol Use
The current study investigates the effects of two potential alcohol treatment medications on drinking in a laboratory setting. Aripiprazole (APZ), effects dopamine and serotonin receptors with fewer limiting side effects seen…
- Trial name
- AT (NCT00884884)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)