Clinical trials: Alcohol Addiction, open to volunteers
Alcohol Use Disorder (AUD)
OEA for Young Adults With Alcohol Use Disorder
The goal of this clinical trial is to evaluate the effects of oleoylethanolamide (OEA) supplementation on inflammation, the oral microbiome, neurocognitive function, and alcohol use in young adults ages 18 to 25 with alcohol use…
- Trial name
- NCT07503782
- Testing
- oleoylethanolamide
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Substance Use Disorders
Modification of Inhibitory Control and Craving Through Transcranial Direct Current Stimulation (tDCS) as an Add-On Treatment for Substance Use Disorder
The aim of this project is to investigate the potential of transcranial direct current stimulation (tDCS) to reduce cognitive deficits and substance craving in individuals with substance use disorders (SUD), with a focus on…
- Trial name
- NCT06959342
- Testing
- Transcranial direct current stimulation (tDCS), Inhibition Training
- Where
- 2 sites in Germany
- Volunteers
- 162 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Alcohol Use Disorder, Alcohol-related Liver Disease
Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease
This protocol describes a randomized controlled trial testing the effectiveness and implementability of the CHESS Health Connections smartphone application among patients with alcohol-associated liver disease (ALD) at two medical…
- Trial name
- IMPACT-ALD (NCT06305624)
- Testing
- Connections App
- Where
- 3 sites in United States
- Volunteers
- 298 people
- Sponsor
- University of Wisconsin, Madison
Alcohol Use Disorder, Alcoholism
Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use
During the first funding period (1st FP) we investigated the impact of acute and chronic stress (Trier Social Stress Test, TSST) on Pavlovian-to-instrumental transfer (PIT).
- Conditions
- Alcohol Use Disorder, Alcoholism, Stress Reaction, Ostracism
- Trial name
- ReCoDe (NCT06256952)
- Testing
- PIT paradigm, social exclusion (Cyberball task), Saliva samples
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Alcohol Use Disorder (AUD), Alcohol-Related Disorders
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.
- Conditions
- Alcohol Use Disorder (AUD), Alcohol-Related Disorders, Alcohol Use
- Trial name
- NCT06070649
- Testing
- 0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion, 0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion, 25 mg Diphenhydramine (5 min) + Normal Saline
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Yale University
Alcohol Use Disorder (AUD)
Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder
Alcohol use disorder (AUD) is the second highest preventable cause of death in France. Only 3% of patients are prescribed approved drugs for reducing alcohol consumption or maintenance of abstinence.
- Trial name
- MBRP (NCT04598399)
- Testing
- Mindfulness Based Relapse Prevention, Relaxation/ meditation
- Where
- 7 sites in France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Alcohol Use Disorder, Insomnia
Mobile App Intervention for Sleep Problems and Alcohol Use Among Veterans
The goal of this clinical trial is to test the preliminary efficacy of a brief mobile app targeting insomnia symptoms among veterans.
- Trial name
- NCT06487793
- Testing
- Enhanced Insomnia Coach, Sleep hygiene comparator
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity
Situation and Evolution of the Misuse of Alcohol and Other Addictive Behaviors in Obese Patients Being Managed at Nîmes University Hospital
Obesity is a multifactorial pathology in which external (lifestyle, environment) and internal (psychological or biological, especially genetic) factors are involved. These are responsible for a positive energy balance.
- Trial name
- ADOB (NCT04613791)
- Testing
- Blood test
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes