Clinical trials: Alcohol Consumption
Alcohol Use Disorder
Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects
Impulsivity is a central feature of addiction. Nalmefen is an authorized treatment for alcohol addiction. Baclofen has empathically been advocated to have some efficacy in this indication.
- Trial name
- NCT03034408
- Testing
- Nalmefene, Baclofen
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Prof. Daniele Zullino
Alcohol Use Disorder
Automated Reinforcement Management System (ARMS)
Alcohol abuse remains a significant cause of preventable morbidity and mortality in the US. Yet only 15% of those with alcohol use disorders receive treatment.
- Trial name
- ARMS (NCT04656925)
- Testing
- Contingency management
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Washington State University
Bariatric Surgery, Alcohol Consumption
Effect of Moderate Alcohol Consumption to Cognitive Functioning After Roux-en Y Gastric Bypass
Objectives: Alcohol metabolism is changed in gastric bypass patients, leading to faster resorption and higher alcohol peak concentrations in blood.
- Conditions
- Bariatric Surgery, Alcohol Consumption, Cognitive Function
- Trial name
- NCT02380950
- Testing
- 250 ml alcohol consumption
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- eSwiss Medical & Surgical Center
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Alcohol Dependence
Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use
The purpose of this study is to explore the treatment effects of Selincro in alcohol dependent patients with liver impairment.
- Trial name
- NCT02197598
- Testing
- nalmefene
- Where
- 3 sites in Germany
- Volunteers
- 45 people
- Sponsor
- H. Lundbeck A/S
Alcohol Drinking, Alcohol Abuse
Using Counter Attitudinal Advocacy to Change Drinking Behavior
High volume drinking by young adults has proven resistant to change, so new approaches are needed. We adapt a theory-based attitude change strategy for use in alcohol prevention.
- Trial name
- NCT04042909
- Testing
- Counter Attitudinal Advocacy, Personalized Normative Feedback
- Where
- 2 sites in United States
- Volunteers
- 591 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Use, Unspecified, Homelessness
Life Enhancing Alcohol-management Program
People experiencing chronic homelessness comprise a small yet high-morbidity, high-cost subset of the larger homeless population and are disproportionately impacted by alcohol-related harm.
- Conditions
- Alcohol Use, Unspecified, Homelessness, Harm Reduction, Community Based Participatory Research
- Trial name
- LEAP (NCT04302740)
- Testing
- LEAP
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Washington
Post-Traumatic Stress Disorder, Alcohol Use Disorder
Resolving Psychological Stress
The investigators have developed a mobile app called Resolving Psychological Stress (REPS) to help alleviate symptoms of PTSD. The app will administer threat-related attention bias modification to individuals who have both a…
- Trial name
- RePS (NCT03996876)
- Testing
- RePS (Resolving Psychological Stress) - Threat ABM Training, RePS (Resolving Psychological Stress) - Neutral Attention Training
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
Alcoholism, Alcohol Related Disorders
Laboratory Studies on Oxytocin for Treatment of Alcohol Use Disorder
This study will examine the utility of the neuropeptide oxytocin (OT) as a potential new medication for the treatment of Alcohol use disorder (AUD).
- Trial name
- NCT02407340
- Testing
- oxytocin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University
Coronary Heart Disease
Alcohol Consumption and Coronary Heart Disease Onset
The primary aim of this study is to examine if long-term patterns of alcohol consumption are associated with time-to-onset for incident coronary heart disease (fatal and non-fatal), using data from multiple cohorts.
- Trial name
- NCT03133689
- Where
- United Kingdom
- Volunteers
- 35,132 people
- Sponsor
- University College, London
Alcohol Use Disorder (AUD), Obesity (BMI Equal to or >30)
Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
This study will examine two doses of 1.0 mg and 2.0 mg of Semaglutide versus placebo in patients with Alcohol Use Disorder (AUD) and Obesity (Ob) to assess if these doses improve alcohol craving, stress and alcohol use outcomes.
- Trial name
- SEMA AUD (NCT07772960)
- Testing
- Semaglutide 1.0 mg, Semaglutide 2.0 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Yale University
Alcohol Use Disorder (AUD), Alcohol Abuse
Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs)
Harmful alcohol use is a global risk factor for disease, injuries and death. Research on treatment of Alcohol use disorders (AUDs) indicates that different treatment modalities are equally effective, but also that a large group…
- Conditions
- Alcohol Use Disorder (AUD), Alcohol Abuse, Drug Abuse, Psychiatric Disorder
- Trial name
- NCT04822987
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- The Hospital of Vestfold
Posttraumatic Stress Disorder, Depression
Trauma Survivors Outcomes and Support Study IV
After traumatic injuries some people have difficulty returning to the routine of their everyday activities and may experience physical and emotional pain.
- Conditions
- Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury
- Trial name
- TSOS IV (NCT01625416)
- Testing
- Stepped Care Management
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Washington
HIV Infection, Alcohol Use
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort
The purpose of this study is to expand and continue a cohort of HIV-infected adults to establish the longitudinal Boston ARCH Cohort of 250 HIV-infected men and women with current substance dependence or ever injection drug use…
- Conditions
- HIV Infection, Alcohol Use, Bone Disease, Substance-Related Disorders
- Trial name
- NCT01740115
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Smoking Cessation, Alcohol Use
Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors
This study will examine the efficacy of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) compared to standard care among cancer survivors who smoke cigarettes and engage in at-risk alcohol use.
- Trial name
- NCT07447635
- Testing
- Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA), Quitline Support
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Alcool Use Disorder
Effectiveness of Virtual Reality Therapy in Alcohol Use Disorder Study
Intro: Virtual reality exposure therapy (VRET) has been widely assessed in several mental disorders, including substances use disorders.
- Trial name
- e-ReVA (NCT06104176)
- Testing
- CBT in group, Virtual reality exposure, individual CBT
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Opioid-use Disorder, Cocaine Use Disorder
Navigation Services to Avoid Rehospitalization (NavSTAR)
This study will examine the clinical effectiveness and health economic profile of services to link hospital patients with substance use disorders to addiction treatment, promote their medical stabilization, and reduce hospital…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Alcohol Use Disorder
- Trial name
- NavSTAR (NCT02599818)
- Testing
- NavSTAR
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Friends Research Institute, Inc.
Father-Child Relations, Depression
Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya
The goal of this study is to evaluate the feasibility and acceptability of a peer-father counselor delivered psychosocial intervention for fathers at risk for depression and some alcohol use in Eldoret, Kenya in a pilot…
- Conditions
- Father-Child Relations, Depression, Alcohol Use, Unspecified
- Trial name
- NCT06489314
- Testing
- LEAD (Learn, Engage, Act, Dedicate)
- Where
- Kenya
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Florida International University
Alcohol Consumption
Reducing Driving Offenses of Adolescent Drinkers
To determine the effectiveness of four group session of motivational counseling plus six hours of direct observations of the emergency department trauma services in comparison to four group session and six hours of community…
- Trial name
- ROAD (NCT00851058)
- Testing
- Brief group counseling, Community Counseling, Prototypic community service
- Where
- United States
- Volunteers
- 786 people
- Sponsor
- Rhode Island Hospital
Alcohol Drinking, Chronic Pain
Mobile App-based Approach for Reducing Pain and Hazardous Drinking: a Pilot Study
Chronic pain and heavy drinking are common co-occurring conditions among patients presenting to primary care settings. Given their impact on functioning and medical outcomes, there would be considerable benefit to developing an…
- Trial name
- NCT06281821
- Testing
- mhealth-pc
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Boston University Charles River Campus