Clinical trials: Alcohol Craving, open to volunteers
Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification
Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving
Cannabidiol (CBD), one of the most prevalent cannabinoids in cannabis (marijuana) has been shown to reduce alcohol withdrawal symptoms in laboratory animals.
- Conditions
- Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification, Craving
- Trial name
- NCT07148843
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Johns Hopkins University
Alcohol Use Disorder, Inflammatory Response
Endotoxin Exposure to Examine the Role of Inflammation in Alcohol Use
The study design consists of a randomized, double-blind, placebo-controlled study of low dose endotoxin. Individuals with current AUD (n=32) and matched controls without AUD (n=32) will be randomly assigned to receive a single…
- Conditions
- Alcohol Use Disorder, Inflammatory Response, Craving
- Trial name
- NCT07452146
- Testing
- Endotoxin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcohol Use Disorder (AUD), Alcohol Consumption
Probenecid Administration for Alcohol Craving and Consumption
This study proposes a 16-week, between-subject, double-blind, randomized controlled trial (RCT) with probenecid (2g /day) compared to placebo in individuals with AUD to test if reduces craving and alcohol consumption.
- Conditions
- Alcohol Use Disorder (AUD), Alcohol Consumption, Craving
- Trial name
- PROB2 (NCT07118618)
- Testing
- Probenecid Oral Tablet
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brown University
Craving, Alcohol Drinking
Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students
The goal of this clinical trial is to examine whether dynamic visual noise (DVN), a short video array of rapidly moving black and white squares, reduces cravings for and consumption of alcohol in college students who drink…
- Trial name
- NCT07157124
- Testing
- Dynamic Visual Noise (DVN), Static Visual Noise (SVN)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Wyoming
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Alcohol Abuse, Craving
Using Neurofeedback to Understand the Relationship Between Stress and Alcohol Consumption
In this research project, the aim is to discover the role specific brain networks play in the relationship between stress reactions and the desire for alcohol and alcohol consumption.
- Conditions
- Alcohol Abuse, Craving, Psychosocial Stressor, Neural Stress Response
- Trial name
- NeuStress (NCT06247306)
- Testing
- ScanSTRESS fMRI-paradigm (Streit et al., 2014), real-time fMRI neurofeedback
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Central Institute of Mental Health, Mannheim