Clinical trials: Alcohol Disorders
Alcohol Use Disorder
Understanding Genetic Risk for Alcohol Use Disorder
The purpose of this study is to evaluate an online educational tool that will help individuals better understand alcohol use disorder, risk factors, and genetic risk information and to better understand participant's beliefs…
- Trial name
- NCT05143073
- Testing
- Alcohol use disorder and strategies to reduce risk educational material, Complex polygenic risk scores, alcohol use disorder, and strategies to reduce risk educational material
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Alcohol Abuse
Optimisation of Functional MRI-based Neurofeedback for Alcohol Use Disorders
Participants will undergo a single session of functional magnetic resonance imaging (fMRI)-based neurofeedback (approximately 1 hour).
- Trial name
- NCT02406456
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Hepatobiliary Diseases
Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases
The investigators hypothesize that the extent of sulfation of toxic BAs and their urinary elimination can be used as a biomarker to predict the severity and prognosis of hepatobiliary diseases.
- Trial name
- NCT01200082
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Alcohol Withdrawal Delirium
Treatment Of Alcohol Withdrawal Syndrome: Dexmedetomidine Vs Diazepam In A Hospital O'horán
The cessation of alcohol consumption of people suffering from alcohol abuse frequently leads to the development of an alcohol withdrawal syndrome (AWS).
- Trial name
- NCT03877120
- Testing
- Dexmedetomidine 0.004 MG/ML, Diazepam Injectable Solution
- Where
- Mexico
- Volunteers
- 2 people
- Sponsor
- Centro Medico Nacional La Raza, IMSS
Substance-Related Disorders
Medical Office Intervention for Adolescent Drug Use
The goal of this study is to assess the efficacy of a new intervention based on motivational enhancement therapy among adolescents with a history of substance use.
- Trial name
- NCT00229983
- Testing
- Motivational Enhancement Therapy
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Boston Children's Hospital
Alcoholism, Substance-Related Disorders
Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study
This study is an assessment of the long-term effect of oxytocin nasal spray on alcohol withdrawal and dependence in adults admitted for detoxification of alcohol after 60 days and 1 year.
- Trial name
- NCT03339024
- Testing
- intranasal oxytocin spray, intranasal spray without oxytocin
- Where
- Norway
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Alcohol Use Disorder, Posttraumatic Stress Disorder
Mobile Mindfulness for Alcohol Use and PTSD Among Veterans
The purpose of the present study is to develop and test a mobile mindfulness intervention for Alcohol Use Disorder and PTSD among OEF/OIF veterans
- Trial name
- NCT04769986
- Testing
- Mobile Mindfulness-Relapse Prevention (mMBRP), Exercise/healthy eating mobile app
- Where
- 3 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Coronary Heart Disease
The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease
To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease.
- Trial name
- NCT00382551
- Testing
- Moderate daily consumption of Red wine, Moderate daily consumption of beer, Moderate consumption of fruit juice rich in polyphenolics
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- Aalborg University Hospital
Opioid Use Disorder, Alcohol Use Disorder
Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
The opioid epidemic has become one of America's deadliest crises, surpassing car crashes, firearms, and HIV/AIDS as a leading cause of death for Americans under fifty years of age.
- Conditions
- Opioid Use Disorder, Alcohol Use Disorder, Health Risk Behaviors, Criminal Behavior
- Trial name
- RB (NCT05665179)
- Testing
- Removing Barriers to Recovery
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Michigan
Alcohol Dependence
Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence
This study will test the safety and efficacy of the PROMETA® Treatment Protocol (which includes the benzodiazepine antagonist flumazenil) in reversing the neurocognitive impairment and this in turn will lead to improved ability…
- Trial name
- NCT00570388
- Testing
- Prometa Treatment Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Institute of Addiction Medicine
Alcohol and Substance-Related Mental Disorders, Sexually Transmitted Diseases
Women SHARE Study: Reducing Sexual Risk
This study will investigate whether BI and technology extenders are feasible and acceptable for female patients at a reproductive health center (ages 18-29).
- Trial name
- HIV (NCT03323086)
- Testing
- Brief Intervention (BI) with Technology Extender, Brochure
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Substance Use Disorders
The Effects of an Acute Bout of Exercise on Alcohol and Cocaine Craving - an fNIRS Study
The study is a crossover randomised controlled trial. Alcohol or cocaine dependent participants will be recruited from inpatient and outpatient psychiatric treatment centres, on the approval of their treating physician.
- Trial name
- ExAlCo (NCT03502486)
- Testing
- Moderate exercise, Intense exercise, Reading
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Basel
Alcohol-Related Disorders
Exercise as Alcohol Use Disorders Intervention for Non-Treatment Seeking Adults
Alcohol use disorders are common and few individuals with the disorder ever seek help. This study proposes to intervene in a novel way - exercise, as it has many mental and physical health benefits and is an activity that is…
- Trial name
- NCT01399554
- Testing
- Motivational Enhancement Therapy plus Contingency Management
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- St. Louis University
Alcoholic Hepatitis
Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis
This multicenter, randomized, double blinded, placebo-controlled clinical trial is focused on novel treatments for severe alcoholic hepatitis (AH), a life-threatening stage of alcoholic liver injury that has a short-term…
- Trial name
- AlcHepNet (NCT04072822)
- Testing
- Anakinra and Zinc, Prednisone
- Where
- 10 sites in United States
- Volunteers
- 147 people
- Sponsor
- Indiana University
Drinking, Binge
Multisensory Processing of Alcohol Cues in Young Adult Binge Drinkers
Binge drinking is common among young adults and is related to many negative health outcomes including blackouts, risky sex, drunk driving, alcohol use disorder, and liver disease.
- Trial name
- NCT06885190
- Testing
- Presentation of alcohol-related and neutral stimuli
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
Alcohol Dependence
The Efficacy and Neurobehavioural Mechanism of N-acetyl Cysteine (NAC) for Alcohol Dependence
The study will explore the efficacy and tolerability of a regimen of NAC (2400 mg) versus placebo for the treatment of alcohol dependence.
- Trial name
- NCT03879759
- Testing
- NAC 2400mg/day
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South West Sydney Local Health District
MASLD, Liver Cirrhosis, Alcoholic
Acquisition of Cardiac Function Parameters in MRI and Echocardiography in Patients With Ethyltoxic Liver Cirrhosis and Transjugular Intrahepatic Portosystemic Shunt (TIPSS) Placement
The aim of this clinical trial is to investigate the development of cardiac decompensation following transjugular intrahepatic portosystemic shunt (TIPSS) implantation in order to draw conclusions for future treatment methods or…
- Conditions
- MASLD, Liver Cirrhosis, Alcoholic, Cirrhosis of Liver, Heart Decompensation
- Trial name
- EVALUATION (NCT06814990)
- Testing
- Cardiac MRI, Blood samples, Echocardiography
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Stephanie Gräger
Alcohol Use Disorder, Alcohol Dependence
Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study
Alcohol use disorder (AUD) is a complex chronic brain disease characterized by compulsive alcohol use, loss of control over drinking, and negative emotional states.
- Conditions
- Alcohol Use Disorder, Alcohol Dependence, Alcohol Consumption
- Trial name
- TMS (NCT06770556)
- Testing
- Active iTBS, 10 Hz TMS, 1 Hz TMS
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Alcohol Abuse, Tobacco Use Disorder
Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking
The goal of this project is to evaluate the feasibility, acceptability, and effect size of a new computerized Motivational Enhancement Therapy (cMET) intervention for alcohol-involved adolescents in primary care.
- Conditions
- Alcohol Abuse, Tobacco Use Disorder, Substance Use
- Trial name
- NCT01881841
- Testing
- cMET
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Boston Children's Hospital
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