Clinical trials: Alcohol Disorders
Alcohol Use Disorders (AUD)
Mifepristone for the Prevention of Relapses of Alcohol Drinking
The goal of this study is to determine if, under stress, alcohol drinking is reduced using mifepristone
- Trial name
- NCT02243709
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Brown University
Alcoholism
Couples Therapy for Alcoholic Patients
In treating alcoholism, many studies show Behavioral Couples Therapy (BCT) is more effective than typical counseling, but BCT is not widely used because standard BCT delivered one couple at a time is costly to deliver and does…
- Trial name
- CALM (NCT01659957)
- Testing
- Group Couples Counseling, One-on-One Couples Counseling
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- Harvard University
Alcoholic Liver Cirrhosis
Long-Term Follow-up of Patients With Alcoholic Liver Cirrhosis Treated With Cellgram-LC
The goal of this observational study is to learn about the long-term safety of Cellgram-LC in patients with alcoholic liver cirrhosis who previously received Cellgram-LC in the PMC-P-07 study.
- Trial name
- NCT05093881
- Where
- 14 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Pharmicell Co., Ltd.
Asthma
A Pilot Evaluation of the Impact of Alcohol Use on Airway Inflammation and Mechanics in Asthmatics
Since 1980, the number of people in the United States diagnosed with asthma has increased dramatically. Studying what causes and triggers asthma is an important part of understanding and subsequently managing this disease.
- Trial name
- AIM Asthma (NCT00615407)
- Sponsor
- Emory University
Alcohol Use Disorder
Scale-up of Prevention and Management of Alcohol Use Disorders and Comorbid Depression in Latin America
A quasi-experimental study will compare primary health care-based prevention and management of alcohol use disorder, operationalized by heavy drinking, in three intervention cities from Colombia, Mexico and Peru with three…
- Trial name
- SCALA (NCT03524599)
- Testing
- Intervention municipality
- Where
- Colombia
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Neutropenia
Mouthwash With Chlorhexidine 0.12%/Ethyl Alcohol 7% Compared to Ethyl Alcohol 7%
Clinical triple-blind randomized controlled trial to assess the use of two different mouthwashes to reduce the oral colonization by gramnegative bacteria in patients with chemotherapy
- Trial name
- NCT02414581
- Testing
- chlorhexidine 0.12%/Ethyl alcohol 7%, Ethyl Alcohol 7%, Chlorhexidine 2%/Ethyl alcohol 7%
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Lysosomal Acid Lipase Deficiency
Clinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase Deficiency
This was an open-label, repeat-dose, study of sebelipase alfa in infants with rapidly progressive lysosomal acid lipase deficiency (LAL-D). Eligible participants received once-weekly infusions of sebelipase alfa for up to 3 years.
- Trial name
- NCT02193867
- Testing
- Sebelipase Alfa
- Where
- 5 sites in United States, Finland and 2 more
- Volunteers
- 10 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
HIV Infections
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial
YouTHrive (YT) is a two-arm randomized control trial (RCT) to test the efficacy of an adapted version of the Thrive With Me (TWM) intervention for youth living with HIV (YLWH).
- Trial name
- NCT03149757
- Testing
- YouTHrive, Information-only Control
- Where
- 7 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alcohol Use Disorders
Effectiveness and Costs of Internet-based Treatment for Harmful Alcohol Use and Face-to-face Treatment in Addiction Care
The purpose of this trial is to compare the effectiveness and costs of a five-module Internet-based treatment program (including therapist support) for harmful alcohol use with the effectiveness and cost of the same treatment…
- Trial name
- NCT02671019
- Testing
- Guide to better alcohol habits
- Where
- Sweden
- Volunteers
- 303 people
- Sponsor
- Karolinska Institutet
Alcohol Use Disorder
Cognitive and Metacognitive Remediation in Addiction Treatment.
Cognitive and metacognitive remediation in addiction treatment: Value of Adding a cognitive remediation program to improve overall self-efficacy in patients with alcohol use disorder.
- Trial name
- R'COMET (NCT07390877)
- Testing
- cognitive remediation group, Relaxation control program
- Where
- 6 sites in France
- Volunteers
- 130 people
- Sponsor
- Nantes University Hospital
Alcohol Use Disorder, Posttraumatic Stress Disorder
Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship
Intimate partner violence (IPV) is a serious public health problem that results in significant health and economic burdens including mortality, morbidity, and poor treatment outcomes.
- Conditions
- Alcohol Use Disorder, Posttraumatic Stress Disorder, Couples
- Trial name
- NCT05786157
- Testing
- Alcohol Administration
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Medical University of South Carolina
Postoperative Complications, Alcohol Use Disorder
Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
This study aims to see if there's a link between a substance called phosphatidylethanol (PEth) and how patients who have surgery at University Hospitals do after surgery.
- Trial name
- NCT06864819
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- University Hospitals Cleveland Medical Center
Alcohol Use Disorder
AAT for Alcohol Use Disorder in Veterans
The proposed study will test a novel treatment for alcohol use disorders (AUD) to determine if it helps Veterans reduce their hazardous drinking and recover from alcohol-related functional impairments across social, occupational…
- Trial name
- NCT05372029
- Testing
- Approach Avoidance Training
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- VA Office of Research and Development
Alcoholism
GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
This Project will explore the hypothesis that individuals with a family history positive for alcohol dependence (without any current Axis I disorder, except nicotine dependence), experience an alteration in the reward "valence"…
- Trial name
- NCT00611767
- Testing
- Thiopental
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Dependence
ALK21-003EXT: An Extension of Study ALK21-003 (NCT01218958) to Test the Long-term Safety of Medisorb® Naltrexone (VIVITROL®)
This was a Phase 3 multicenter extension of Alkermes' Study ALK21-003 (NCT01218958 [the base study]) that evaluated the safety of Medisorb® naltrexone (VIVITROL®) administered every 4 weeks for 48 weeks (13 injections) in…
- Trial name
- NCT01218971
- Testing
- Medisorb naltrexone 190 mg, Medisorb naltrexone 380 mg
- Volunteers
- 332 people
- Sponsor
- Alkermes, Inc.
Alcohol Dependence
Combination of Naltrexone and Baclofen for Alcohol Dependence:A Pilot Study.
The purpose of this research study is to learn about the use of a combination of two medications, baclofen and naltrexone, for the treatment of alcohol dependence in men and women ages 25-60 years old.
- Trial name
- NCT00614328
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alexithymia, Alcohol Use Disorder
Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder
Art therapy support combined with standard care for people with an alcohol use disorder coming to a day hospital for withdrawal could be beneficial compared to standard care alone because it would improve the alexithymia of these…
- Trial name
- ALEXART (NCT04206930)
- Testing
- Art Therapy
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Alcoholism, Gambling
Effectiveness of Sertraline in Treating Pathological Gamblers With a Diagnosis of Alcohol Dependence - 1
Pathological gamblers often are also dependent on alcohol and clinically depressed. Sertraline (Zoloft) is currently used to treat depression, panic disorder, and obsessive-compulsive disorder.
- Trial name
- NCT00249431
- Testing
- Sertraline, Relapse Prevention Therapy
- Volunteers
- 9 people
- Sponsor
- New York State Psychiatric Institute
Tobacco Use Disorder, Alcohol Use Disorder
Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth
The goal of this project is to evaluate the effectiveness of a family-based tobacco use prevention intervention directed at immigrant Latino parents of middle school aged youth as delivered in partnership with seven community…
- Conditions
- Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking
- Trial name
- NCT01442753
- Testing
- Family-Skills Training
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.