Clinical trials: Alcohol Disorders
Alcohol-Related Disorders, Alcohol Use Disorders
Adaptive Interventions for Problem Drinkers
The purpose of this study is to understand how certain interventions help people reduce or quit their drinking and how certain interventions may help best at certain points in time in the change process.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT02511808
- Testing
- Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Northwell Health
Alcoholism
Naltrexone, Craving, and Drinking
This 5-week study will examine the effects of naltrexone on alcohol craving, drinking rates, and reaction to drinking-related triggers, or cues, in participants' everyday environment and in laboratory sessions.
- Trial name
- NCT00006203
- Testing
- Naltrexone 50 Mg
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Brown University
Alcoholic Liver Disease
THE IMMUNOLOGICAL EFFECTS AND METABOLIC TOLERANCE OF LIPID INFUSION IN PATIENTS WITH CIRRHOSIS.
The study will be an experimental pre-post trial in which patients with ethanol related liver disease (both severe alcoholic hepatitis and decompensated ) admitted in our institute from Jun 2013-Dec 2014 will be enrolled in the…
- Trial name
- NCT02381769
- Testing
- Soybean based lipid emulsion
- Where
- India
- Volunteers
- 55 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Healthy Volunteers, Alcohol Drinking Related Problems
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
Background: Problem drinking affects nearly half the people who drink alcohol. Drinking alcohol affects a person's social behavior and brain structure, but researchers don't have a good understanding of how.
- Conditions
- Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
- Trial name
- NCT03535129
- Testing
- Real time fMRI neurofeedback
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alcoholic Hepatitis
Pegfilgrastim in Patients With Alcoholic Hepatitis
This is a multi-center, prospective, randomized trial of standard of care vs. standard of care + pegfilgrastim (Neulasta®) among patients with a clinical diagnosis of alcoholic hepatitis and DF≥32.
- Trial name
- NCT02776059
- Testing
- Standard of care + pegfiltrastim, Standard of care
- Where
- 5 sites in United States
- Volunteers
- 34 people
- Sponsor
- Timothy Morgan, MD
Fetal Alcohol Spectrum Disorders
Dissecting the Genetics of Fetal Alcohol Spectrum Disorders
The purpose of this study is to help scientists understand why some people who were exposed to alcohol in the womb have special facial features but other people do not.
- Trial name
- DiGFASD (NCT04072809)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Indiana University
Acute Alcoholic Hepatitis
Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis
This study will compare two different treatments of acute alcoholic hepatitis. The current standard of care is treatment with corticosteroids (methylprednisolone).
- Trial name
- NCT01809132
- Testing
- Anakinra, Pentoxifylline, Zinc Sulfate
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Mack Mitchell
Alcoholism
Alcoholism: Emotion and Thinking
The purpose of this study is to determine whether long-term chronic alcoholism is associated with changes in emotional functioning and brain structure and function.
- Trial name
- NCT00300638
- Testing
- Magnetic Resonance Imaging (MRI), Interviews, cognitive tests, and emotional measurements
- Where
- United States
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcoholism, Depression
Sertraline and Cognitive Therapy in Depressed Alcoholics
This study will assess whether individuals treated with sertraline (Zoloft) and cognitive behavior therapy will experience improvement with their depression and consume less alcohol than individuals treated with a placebo and…
- Trial name
- NCT00000458
- Testing
- sertraline (Zoloft), cognitive behavior therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder
Ibudilast for the Treatment of Alcohol Use Disorder
This study is a double-blind, placebo-controlled randomized clinical trial of Ibudilast (IBUD) (50mg twice a day) for the treatment of Alcohol Use Disorder (AUD).
- Trial name
- NCT03594435
- Testing
- Ibudilast
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of California, Los Angeles
Bipolar Disorder
Cognitive-Behavior Therapy for Young Adults With Bipolar Disorder
The aim of the study is to develop and pilot test a cognitive-behavioral (CBT) intervention for young adults, ages 18-24 with bipolar disorder.
- Trial name
- NCT01176825
- Testing
- cognitive-behavior therapy (CBT)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Massachusetts General Hospital
Alcohol Abuse
Web Intervention for Concerned Partners to Prevent Service Member Alcohol Abuse Abuse
The purpose of this study is to adapt and pilot-test a web-based intervention intended to help concerned partners provide support to service members with alcohol misuse and to begin development of a service member module based on…
- Trial name
- PC (NCT02073825)
- Testing
- Web Brief Intervention (WBI)
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- RAND
Fatty Liver Without Mention of Alcohol
A Clinical Study of Curcuvail® in Patients With Non-alcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. It comprises a wide spectrum of disorders that range from simple steatosis to nonalcoholic steatohepatitis (NASH), advanced fibrosis…
- Trial name
- NAFLD (NCT06256926)
- Testing
- Test Product: Curcuvail® 250mg capsule (Curcuma longa Extractcontaining 35% Curcuminoids)
- Where
- India
- Volunteers
- 30 people
- Sponsor
- COD Research Private Ltd
Cocaine Abuse, Cocaine Dependence
Substance Abuse Pre-Treatment Screening Study
The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for…
- Conditions
- Cocaine Abuse, Cocaine Dependence, Opiate Dependence, Alcohol Dependence
- Trial name
- NCT00439049
- Testing
- modafinil, d-amphetamine, L-Dopa
- Where
- United States
- Volunteers
- 7,500 people
- Sponsor
- The University of Texas Health Science Center, Houston
Alcohol-related Liver Disease
Alcohol Biomarkers in Post-Liver Transplant Patients
The aim of this study is to compare the predictive validity and reliability of PEth testing at detecting alcohol use in post liver transplant patients. A prospective cohort study will be used to test the primary hypothesis.
- Trial name
- NCT01812226
- Where
- 2 sites in United States
- Volunteers
- 214 people
- Sponsor
- Northwestern University
Human Immunodeficiency Virus, Alcohol-Related Disorders
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
The purpose of this study is to evaluate a stepped care behavioral intervention for HIV medication adherence and substance use ("Khanya") integrated into an HIV primary care setting in South Africa.
- Conditions
- Human Immunodeficiency Virus, Alcohol-Related Disorders, Drug Use, Substance Use
- Trial name
- NCT05933226
- Testing
- Khanya
- Where
- South Africa
- Volunteers
- 160 people
- Sponsor
- University of Maryland, College Park
Alcohol Associated Hepatitis
FXR Effect on Severe Alcohol-Associated Hepatitis (FRESH) Study
The purpose of this trial is to assess dose related safety, efficacy, and pharmacokinetics (PK) of INT-787 in participants with severe alcohol-associated hepatitis (sAH).
- Trial name
- FRESH (NCT05639543)
- Testing
- INT-787
- Where
- 29 sites in United States, France and 1 more
- Volunteers
- 67 people
- Sponsor
- Intercept Pharmaceuticals
Opioid Use, Alcohol Use Disorder
rTMS as Add on Treatment for Substance Use Disorders
This pilot study is designed to test feasibility and superiority of rTMS types and target locations for the optimal rTMS intervention for individuals seeking treatment for Alcohol Use Disorder (AUD) or Opioid Use Disorder (OUD).
- Trial name
- NCT06963476
- Testing
- repetitive transcranial magnetic stimulation (rTMS) for AUD, repetitive transcranial magnetic stimulation (rTMS) for OUD
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Yale University
Alcohol-related Liver Disease
Contingency Management to Incentivise Treatment Adherence in Alcohol-related Liver Disease
A sample of 30 alcohol-related liver disease patients will be recruited through consecutive sampling, facilitated through the Alcohol Care Team, which will identify potential participants to the study that have been referred to…
- Trial name
- NCT06183710
- Testing
- Contingency management
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Liver Diseases, Alcoholic, Alcoholism
Integrated Stepped Care for Unhealthy Alcohol Use in HIV
The study is a series of 3 linked randomized clinical trials of 6 month duration, with a total of 12 month follow-up, to evaluate the effect of Integrated Stepped Care on drinking outcomes and HIV biologic markers (including VACS…
- Conditions
- Liver Diseases, Alcoholic, Alcoholism, HIV, Hepatitis C
- Trial name
- NCT01410123
- Testing
- Integrated Stepped Care (ISC), Treatment as Usual
- Where
- 5 sites in United States
- Volunteers
- 319 people
- Sponsor
- Yale University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.