Clinical trials: Alcohol Disorders
HIV, Acquired Immunodeficiency Syndrome
Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients
This randomized clinical trial uses a health plan's electronic medical record (EMR) alcohol screen; and examines innovative behavioral interventions, and their cost effectiveness, for hazardous drinking within a large HIV primary…
- Conditions
- HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication
- Trial name
- NCT01671501
- Testing
- Motivational Interviewing, Email Feedback, Usual Care
- Where
- United States
- Volunteers
- 614 people
- Sponsor
- University of California, San Francisco
Alcohol Consumption, Insulin Resistance
Identification of Biomarkers for Acute Intake of Beer and Alcohol and Acute Effects on Plasma and Insulin Response
The objective of the study is to identify biomarkers for acute intake of beer and alcohol in individuals with a high or low habitual intake.
- Trial name
- METABEER (NCT02449577)
- Testing
- Beverage sequence ABCD, Beverage sequence CADB, Beverage sequence DACB
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Essential Tremor
Octanol to Treat Essential Tremor
This study will evaluate the effectiveness of 1-octanol, a substance similar to alcohol but less intoxicating, for treating essential tremor.
- Trial name
- NCT00080366
- Testing
- 1-Octanol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alcoholic Liver Cirrhosis, Ascites
Prevention of Decompensation in Liver Cirrhosis
The purpose of this study is to determine whether losartan, an angiotensin II blocker prevents the sodium retention in patients with liver cirrhosis and by that reduces the fluid retention.
- Trial name
- NCT00239096
- Testing
- losartan (drug)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Neuropathic Pain, Anxiety Disorder/Anxiety State
Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer
Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological…
- Conditions
- Neuropathic Pain, Anxiety Disorder/Anxiety State, Pain, Chronic, Alcohol Use Disorder
- Trial name
- DIP-CAOS (NCT05505188)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Drinking, Alcohol
Multimodal Sleep Intervention Using Wearable Technology
This research study is examining three different components of a digital sleep intervention: web-based sleep health advice, sleep and alcohol smartphone diary self-monitoring, and personalized sleep and alcohol consumption…
- Trial name
- NCT03658954
- Testing
- Advice, Self-monitoring, Feedback
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
Study to enroll up to 90 individuals, those with an alcohol use disorder (AUD) (up to n=60) and non-dependent healthy volunteers (HV) (up to n=30).
- Trial name
- AUD (NCT05885594)
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcoholism, Genetics
Genetics of the Acute Response to Alcohol in Social Drinkers
Background: Previous research has shown that a person s genes can influence how they respond to alcohol. But researchers do not yet know all the genes that might be involved.
- Trial name
- NCT01375556
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder (AUD)
Cognitive Rehabilitation Through Personalized Virtual Reality and Paper-and-pencil Interventions in the Alcohol Use Disorder Treatment.
Cognitive dysfunction is one of the different consequences of excessive alcohol consumption, affecting many domains associated with prefrontal and temporal lobes, such as attention, verbal fluency, and memory.
- Trial name
- NCT04639895
- Testing
- Virtual Reality, Paper and Pencil, Control Group
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Universidade da Madeira
Alcohol Use Disorder
Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use Disorder
Background: People with alcohol use disorder (AUD) have trouble controlling their drinking. Medications can help some people with AUD but are not effective for many others.
- Trial name
- NCT03896516
- Testing
- GLWL-01
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcoholism, Alcohol Amnestic Disorder
From Uncomplicated Alcoholism to Korsakoff's Syndrome
This research project aims to identify factors that contribute to the heterogeneity observed in neuroradiological and neuropsychological signs of chronic alcoholism.
- Trial name
- ALCOBRAIN (NCT01455207)
- Testing
- Neuropsychological testing, blood draw, genetic testing
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Alcoholic Hepatitis
Fecal Microbial Transplantation in Severe Alcoholic Hepatitis
1. A subtype of Alcoholic hepatitis (AH), named severe alcoholic hepatitis (SAH) is associated with high short-term mortality (J Hepatol, 2019) 2.
- Trial name
- FMTH7 (NCT04758806)
- Testing
- Fecal microbial transplantation
- Where
- Slovakia
- Volunteers
- 50 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Liver Cirrhosis, Alcoholic
Efficacy of Baclofen in the Treatment of Alcohol Addiction
Intervention to achieve alcohol abstinence represents the most effective treatment for alcoholic patients with liver cirrhosis. However no trials have evaluated the efficacy of anti-craving drugs in these patients because of the…
- Trial name
- NCT00525252
- Testing
- Baclofen
- Volunteers
- 86 people
- Sponsor
- Catholic University of the Sacred Heart
Substance Use Disorder
Substance Use in Elderly Individuals: Brain and Cognitive Correlates and the Effect of Psychotherapy
The prevalence of addictive disorders in old age is increasing. Age specific and appropriate therapeutic concepts tailored to in-patients thus represent a promising approach for the future.
- Trial name
- NCT02835144
- Testing
- TIQAAM_therapy, Psychoeducation
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Prof. Dr. med. Egemen Savaskan
Insomnia
Effects of Insomnia on Simulated Driving (MK-0000-183-00)
This is a double-blind, parallel design study in elderly primary insomnia patients and demographically matched controls. The objectives if this study are primarily: 1.
- Trial name
- NCT01209728
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Alcohol-related Disorders
Evaluation of Case Management to Improve the Outpatient Care of Alcohol-related Disorders
The purpose of this study is to disseminate and transfer the comprehensive quality management interventions (CQM) for alcohol-related disorders in primary care developed during the first funding phase into routine care.
- Trial name
- NCT00314067
- Testing
- Online Comprehensive Quality Management System (CQM) of alcohol-related disorders in primary care, Physician training, Practice team training
- Where
- 2 sites in Germany
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Androgenetic Alopecia
Efficacy Study of a Cosmetic Lotion in the Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to determine whether the Hair Loss Prevention Lotion named MEXIS, M.P.A.F., M6S PATENT is effective in the treatment of Androgenetic Alopecia.
- Trial name
- MEXISPATENT (NCT01701271)
- Testing
- Hair loss prevention lotion
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mexis George
Major Depressive Disorder, Alcohol Use Disorder
Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
To evaluate if naltrexone plus ketamine is effective in reducing depression and alcohol consumption.
- Trial name
- NCT03658330
- Testing
- Ketamine + Naltrexone
- Volunteers
- 5 people
- Sponsor
- VA Connecticut Healthcare System
Alcohol Use Disorder, Alcohol Withdrawal
Digitally Assisted Recovery Coach
The aims of this proof-of-concept study are to determine the feasibility of 1) using a smartphone app ("Lifeguard") to facilitate engagement with a peer recovery coach, 2) monitoring post-detox using a modified Brief Addiction…
- Trial name
- NCT05393544
- Testing
- Digitally assisted peer recovery coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Pregnenolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study
The purpose of this research study is to find out how Zulresso®/brexanolone influences Posttraumatic Stress Disorder (PTSD) symptoms and alcohol use.
- Trial name
- NCT06580444
- Testing
- Brexanolone
- Volunteers
- 40 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
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