Clinical trials: Alcohol Problems
Alcohol Use, Underage, Alcohol Problem Drinking
Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change
This study will be the first to explore mindfulness as a prevention intervention among transition age youth and those with previous involvement in the juvenile or criminal justice system with substance use problems and history of…
- Conditions
- Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
- Trial name
- NCT04160754
- Testing
- Mindfulness Based Relapse Prevention, Control (CTL)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol-Related Disorders, Alcohol Use Disorders
Tailored Mobile Text Messaging to Reduce Problem Drinking
This study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in stopping or reducing their alcohol consumption; and test and compare it to…
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT01885312
- Testing
- Adaptive Tailored Intervention, Consequence-based Intervention, Tailored, not adaptive, based Intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Alcohol Drinking, Alcohol-Related Disorders
Feasibility and Potential Effectiveness of a Case Management Intervention for Alcohol Use-Related Problems in Frequent Users of an Emergency Department: a Pilot Study
Alcohol use and its consequences represent an important public health problem. As well as alcohol dependence, hazardous drinking also contributes to a high burden in terms of morbidity and mortality.
- Trial name
- MALUA_Freq_P (NCT04938258)
- Testing
- Intensive Case Management
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Hospital Clinic of Barcelona
Alcohol Drinking, Alcohol Abuse
Promoting Self-Change From Alcohol Problems: Mechanisms of Change in a Community-Based Intervention
Research has found that natural recovery (self-change) is a very common pathway to change for individuals with alcohol problems, accounting for nearly 75% of recoveries in several national surveys.
- Trial name
- PSC3 (NCT00732095)
- Testing
- Promoting Self-Change with Ads
- Where
- United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Alcohol Use Disorders
Internet Based Cognitive Behavior Treatment for Alcohol Problems
The purpose of this study is to determine whether internet based cognitive behavior therapy might be effective in the treatment of alcohol problems.
- Trial name
- ICBT-AP (NCT02384278)
- Testing
- Internet-based CBT for alcohol problems
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Karolinska Institutet
Chronic Pain, Alcohol Use, Unspecified
St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin
This study is a 3-arm pilot, randomized, double-blinded, placebo-controlled study of low-dose naltrexone and gabapentin versus placebo among HIV-positive persons with heavy alcohol use and chronic pain to provide estimates of…
- Conditions
- Chronic Pain, Alcohol Use, Unspecified, HIV Infections
- Trial name
- UH3 (NCT04052139)
- Testing
- Low-dose naltrexone, Gabapentin
- Where
- Russia
- Volunteers
- 45 people
- Sponsor
- Boston Medical Center
Opioid Use Disorder, Alcohol Use Disorder
Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
The opioid epidemic has become one of America's deadliest crises, surpassing car crashes, firearms, and HIV/AIDS as a leading cause of death for Americans under fifty years of age.
- Conditions
- Opioid Use Disorder, Alcohol Use Disorder, Health Risk Behaviors, Criminal Behavior
- Trial name
- RB (NCT05665179)
- Testing
- Removing Barriers to Recovery
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Michigan
Alcohol Use Disorder, Insomnia
Mobile App Intervention for Sleep Problems and Alcohol Use Among Veterans
The goal of this clinical trial is to test the preliminary efficacy of a brief mobile app targeting insomnia symptoms among veterans.
- Trial name
- NCT06487793
- Testing
- Enhanced Insomnia Coach, Sleep hygiene comparator
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Insomnia, Alcohol Problem
A Timeline Study of Alcohol Use and Its Relationship to Insomnia
This study is an epidemiological and descriptive study of the lifetime relationship of insomnia to alcohol problems.
- Trial name
- NCT00580411
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcoholism, Alcohol Dependence
Baclofen for Treating Anxiety and Alcoholism
Background: Baclofen is a drug used to control muscle stiffness in people with neurological diseases. Some studies suggest that baclofen may reduce alcohol craving and use.
- Conditions
- Alcoholism, Alcohol Dependence, Alcohol Drinking Related Problems, Alcohol Drinking
- Trial name
- NCT01751386
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol-Related Disorders, Alcohol Use Disorders
Adaptive Interventions for Problem Drinkers
The purpose of this study is to understand how certain interventions help people reduce or quit their drinking and how certain interventions may help best at certain points in time in the change process.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT02511808
- Testing
- Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Northwell Health
Drinking, Alcohol
Improving Outcomes for Emergency Department Patients With Alcohol Problems
The investigators will conduct a study to examine the impact of an alcohol peer-mentor intervention starting in the emergency department (ED) combined with 6 peer booster sessions to reduce hazardous drinking and facilitate…
- Trial name
- Project GOAL (NCT03536546)
- Testing
- Alcohol Peer Mentor Intervention, Brief Advice
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- VA Office of Research and Development
Alcohol Abuse, Alcohol Problem
Efficacy of a Brief Alcohol Intervention for Non Dependant Alcohol-misusing Patients Undergoing a Scheduled Surgery
Excessive alcohol consumption is a worldwide major public health problem. Brief interventions have shown to be an efficient treatment modality for problem drinkers, but have never been tested in scheduled surgery.
- Conditions
- Alcohol Abuse, Alcohol Problem, AOD Misuse
- Trial name
- ITBCHIR (NCT01348113)
- Testing
- Brief Alcohol intervention
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Rennes University Hospital
Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders
Helping College Students With ADHD Lead Healthier Lifestyles
There are currently no published randomized controlled studies examining psychosocial interventions for college students with ADHD, and none specifically targeting AUDs in this population at any age, despite the clear indication…
- Conditions
- Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders, Substance-Related Disorders
- Trial name
- NCT02829970
- Testing
- SUCCEEDS Program, Living a Healthy College Lifestyle
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- University of Maryland, College Park
Alcoholism, Alcohol-Related Disorders
A Novel Compound for Alcoholism Treatment
Background: Hormones are naturally occurring chemicals in your body. Ghrelin is a hormone that is mainly produced by the stomach and stimulates appetite. Some studies suggest it may stimulate alcohol craving and use.
- Conditions
- Alcoholism, Alcohol-Related Disorders, Alcohol Dependence, Alcohol Drinking Related Problems
- Trial name
- NCT02039349
- Testing
- PF-05190457
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Post-Traumatic Stress Symptoms, Problematic Use of Alcohol or Other Drugs
Web-based CBT for Recent Veterans Experiencing Problems With Trauma Symptoms or Alcohol/Drug Use
The proposed study involves developing and evaluating an interactive, web-based CBT intervention for OEF/OIF Veterans with hazardous or problematic substance use and PTSD symptoms (PTSD or subsyndromal PTSD).
- Trial name
- Web CBT (NCT01710943)
- Testing
- Web-based Cognitive Behavioral Treatment
- Where
- 2 sites in United States
- Volunteers
- 216 people
- Sponsor
- National Development and Research Institutes, Inc.
Anxiety, Depression
Research of Prevention and Intervention of Mental Health Problems
The purpose of this research is to establish a suitable community-based model for Chinese culture,to improve the community recognition of common mental disorders,as well as its treatment and control.
- Conditions
- Anxiety, Depression, Alcohol-abuse
- Trial name
- RPIMHP (NCT01422447)
- Testing
- regular intervention, community intervention
- Where
- 7 sites in China
- Volunteers
- 42,016 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Drinking, Alcohol Drinking Related Problems
Effects of a New Behavioral Intervention on Alcohol Craving and Drinking
Background: Sights, sounds, and smells can be associated with alcohol and tempt people to drink. The connection between encountering cues and wanting to drink might be reduced by behavioral techniques, like giving the cues at…
- Trial name
- NCT02831049
- Testing
- Retrieval-extinction, Alcohol-related cues, Soft-drink related cues
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Underage Drinking
Facilitating Adolescent Self-Change for Alcohol Problems
This present multi-site investigation compares a voluntary brief intervention for adolescent alcohol problems to an educational comparison condition.
- Trial name
- NCT01690026
- Testing
- Motivation interviewing based brief intervention, Standard Intervention
- Where
- 3 sites in United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Binge Drinking, Suicidal Ideation
Open Pilot Trial Evaluating an Avatar-Guided Intervention for Emerging Adults With Alcohol Use Problems and Suicide Risk
This study is an open pilot usability trial to test the 1) usability of a newly developed mobile health intervention to help manage suicidal ideation and alcohol use problems and 2) feasibility of research protocols with emerging…
- Trial name
- EA-Avatar (NCT06595862)
- Testing
- EA-Avatar
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester