Clinical trials: Alcohol Use Disorder, completed
Alcohol Use Disorder
Increasing the Temporal Window in Individuals With Alcohol Use Disorder
Episodic future thinking (EFT) is based on the new science of prospection, which was first identified in a Science publication in 2007 and refers to pre-experiencing the future by simulation.
- Trial name
- RP1A (NCT04125238)
- Testing
- Episodic Future Thinking, Control Episodic Thinking
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Virginia Polytechnic Institute and State University
Fetal Alcohol Syndrome, Substance Abuse
Fetal Alcohol Damage Prevention Study
The goal of this study was to determine whether a series of blood markers of alcohol use obtained from alcohol using pregnant women could help them to change their behavior.
- Trial name
- NCT00696085
- Testing
- Brief motivational intervention
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic, Substance Use Disorders
Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment
Many people who have posttraumatic stress disorder (PTSD) also struggle with problematic alcohol or drug use (substance use disorders [SUD]). Patients with both conditions prefer PTSD be treated alongside SUD.
- Trial name
- COMPASS (NCT04581434)
- Testing
- Prolonged Exposure Therapy, Cognitive Processing Therapy, Present Centered Therapy
- Where
- 14 sites in United States
- Volunteers
- 426 people
- Sponsor
- Center for Veterans Research and Education
PTSD, Alcohol Use Disorder
BioWare for AUD and PTSD
This study examines the ability of an innovative telehealth technology system to enhance Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure (COPE) talk-therapy for individuals with posttraumatic…
- Trial name
- NCT05187364
- Testing
- COPE
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Depression
Testing a Lifestyle Physical Activity Intervention for Women With Depression in Alcohol Treatment
The primary aim of this project is to test the efficacy of a technology-supported lifestyle physical activity (LPA) intervention for preventing relapse among women with depression engaged in alcohol treatment.
- Trial name
- HEART (NCT04667520)
- Testing
- Lifestyle Physical Activity (LPA), Fitbit Only
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Butler Hospital
Substance Use Disorders (SUD)
Substance-focused SBI as a Complement to Internet-based Psychiatric Treatment: RCT
Objectives: This study evaluates the efficacy of eScreen for internet psychiatry patients treated for major depressive disorder, panic anxiety and social phobia.
- Trial name
- eScreeniPsy (NCT01885026)
- Testing
- eScreen, Assessment only of alcohol and drug use., Internet-based treatment for depression or anxiety
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Karolinska Institutet
Tobacco Dependence, Alcohol Dependence
Effect of Varenicline on Reactivity to Smoking and Drinking Cues
Alcohol and nicotine dependence are often co-morbid, with 85% of alcoholics also smoking. However, very little research has been conducted into the nature of this co-occurrence.
- Trial name
- NCT00873535
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
SARS-CoV-2 Infection, COVID-19
Effect of COVID-19 Lockdown on Alcohol and Tobacco Use in Two Chilean Universities
This is a longitudinal study of participants from two university communities in Chile. The primary objective is to examine the effect of a regional lockdown on alcohol and tobacco use, using a difference-in-difference analysis to…
- Trial name
- NCT05069090
- Testing
- Lockdown and other social distancing measures
- Where
- 2 sites in Chile
- Volunteers
- 1,038 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Nicotine Dependence, Alcohol Use Disorder
Combining Varenicline and Naltrexone for Smoking Cessation
This study is a double-blind, randomized clinical trial using a two group medication design consisting of the combination of VAR (1 mg twice daily) + NTX (50 mg once daily) and VAR (1 mg twice daily) + PLA (matched to NTX), for…
- Trial name
- NCT02698215
- Testing
- Varenicline, Varenicline plus Naltrexone
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- University of California, Los Angeles
Substance Use Disorder (SUD), Alcohol Use Disorder (AUD)
Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community
Theoretical Framework: Cigarette smoking is the leading preventable cause of death worldwide, with nicotine dependence notably common among individuals with Substance Use Disorders (SUD).
- Conditions
- Substance Use Disorder (SUD), Alcohol Use Disorder (AUD), Nicotine Addiction, Healthy Adult Participants
- Trial name
- NCT06803706
- Testing
- 6-weeks CBT smoking cessation programme, Long-term drug therapy within a therapeutic community
- Where
- 3 sites in Austria
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Alcohol Use Disorder
Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 1
Directly reinforcing abstinence from alcohol with monetary incentives is an effective treatment for alcohol dependence, but barriers in obtaining frequent, verified biochemical measures of abstinence limit the dissemination of…
- Trial name
- NCT03883126
- Testing
- Contingency management
- Where
- 3 sites in United States
- Volunteers
- 211 people
- Sponsor
- Mikhail N Koffarnus
PTSD, Alcohol Abuse
Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy
The proposed project aims to: 1. Obtain a preliminary assessment of the efficacy of topiramate treatment in reducing alcohol use in veterans with Post Traumatic Stress Disorder (PTSD) and alcohol dependence; 2.
- Conditions
- PTSD, Alcohol Abuse, Alcoholism
- Trial name
- TAP (NCT01087736)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Alcohol Use Disorders.
D-Cycloserine to Enhance Extinction to Alcohol Cues
There is considerable evidence that Alcohol Use Disorders (AUDs) can be understood as a form of dysregulated learning and are influenced by classical conditioning.
- Trial name
- NCT01362309
- Testing
- d-cycloserine.
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Georgia
Alcohol Use Disorder, Alcohol Withdrawal
Digitally Assisted Recovery Coach
The aims of this proof-of-concept study are to determine the feasibility of 1) using a smartphone app ("Lifeguard") to facilitate engagement with a peer recovery coach, 2) monitoring post-detox using a modified Brief Addiction…
- Trial name
- NCT05393544
- Testing
- Digitally assisted peer recovery coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Bipolar Disorder, Alcohol Drinking
Familial Risk for Bipolar Disorder and Alcohol Sensitivity
Early identification in individuals with bipolar disorder who are at risk for AUDs could inform novel intervention strategies and improve life-long outcomes.
- Conditions
- Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
- Trial name
- FACS (NCT04716036)
- Testing
- Alcohol beverage
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Game Plan for PrEP
This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their…
- Trial name
- NCT04973267
- Testing
- Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Use Disorder (AUD)
Comprehensive Process Model of AA-related Behavior Change
Alcoholics Anonymous (AA) is one of the most popular resources for dealing with alcohol-related problems, and 12-step therapy (TS), based upon AA doctrine and practice, is one of the prevailing alcohol treatment approaches in the…
- Trial name
- NCT04618653
- Testing
- assessment only
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of New Mexico
Alcohol Dependence, Alcohol Drinking
Behavioral and Functional Task Development, Implementation, and Testing
Background: Scientists know that alcohol use disorders affect brain structure. They want to know more about the effects of alcohol use disorders on a person s behavior.
- Conditions
- Alcohol Dependence, Alcohol Drinking, Alcoholism, Alcohol Use Disorder
- Trial name
- NCT02108054
- Testing
- 7T MRI
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Abuse
Optimisation of Functional MRI-based Neurofeedback for Alcohol Use Disorders
Participants will undergo a single session of functional magnetic resonance imaging (fMRI)-based neurofeedback (approximately 1 hour).
- Trial name
- NCT02406456
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Insomnia, Alcohol; Harmful Use
Insomnia Treatment and Problems (the iTAP Study)
This project aims to evaluate the efficacy of insomnia treatment in improving insomnia symptoms and alcohol-related problems among heavy-drinking young adults.
- Trial name
- iTAP (NCT03627832)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep Hygiene
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia