Clinical trials: Alcohol Use Disorder, completed
Use; Tobacco, Harmful, Alcohol Abuse
Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
The purpose of the project is to improve adolescent behavioral counseling services in healthcare settings with a new Internet/Intranet-based Motivational Enhancement Therapy (iMET) intervention that targets the use of tobacco…
- Conditions
- Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
- Trial name
- NCT00907309
- Testing
- iMET, iMET/TE
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Boston Children's Hospital
Alcohol Use Disorder
Phase 1b Study of DCR-AUD in Healthy Volunteers
The goal of this clinical trial is to test the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of of repeat doses of DCR-AUD in adult healthy volunteers who are social drinkers.
- Trial name
- NCT05845398
- Testing
- DCR-AUD
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Insomnia, Alcohol Problem
A Timeline Study of Alcohol Use and Its Relationship to Insomnia
This study is an epidemiological and descriptive study of the lifetime relationship of insomnia to alcohol problems.
- Trial name
- NCT00580411
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Domestic Violence, Substance Abuse
The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug Use
This research is a stage 1b developmental trial evaluating an intervention called "The Men's Domestic Abuse Check-Up" with adult men abusing their intimate partners and also struggling with alcohol or drug use.
- Trial name
- MDACU (NCT01621334)
- Testing
- Motivational Enhancement Therapy, Educational information
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Dependence
Treatment Strategy for Alcohol Use Disorders in Veterans With TBI
The purpose of this research study is to understand the effectiveness of valproate (a common mood stabilizer) to further reduce alcohol misuse when given in addition to attending an alcohol rehabilitation program as well as the…
- Trial name
- AUD (NCT01342549)
- Testing
- Valproate, Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder (AUD)
Multimodal Intervention for GGT Reduction in Alcohol Use Disorder (GGT-AUD)
The aim of this clinical trial is to evaluate whether a combined nutraceutical and psychological intervention can reduce gamma-glutamyl transferase (GGT) levels in individuals with Alcohol Use Disorder (AUD).
- Trial name
- GGT-AUD (NCT07603726)
- Testing
- Alcohol Reduction Counseling, Nutraceutical Treatment, Psychological Intervention
- Where
- Romania
- Volunteers
- 197 people
- Sponsor
- Medical Center TOPMED
Alcohol Use Disorder, Post Traumatic Stress Disorder
Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma
The U.S. Deaf community - more than 500,000 Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure as compared to the…
- Trial name
- NCT03845985
- Testing
- Seeking Safety + Signs of Safety toolkit
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Massachusetts, Worcester
Alcohol Related Disorders, Substance Related Disorders
The Co-Venture Trial: A Cluster Randomized Trial of Personality-targeted Interventions on Adolescent Substance Use and Cognitive Outcomes
The Preventure Program is the first and only school-based alcohol and drug prevention program that has been shown to prevent onset and growth in alcohol and substance misuse in British and Canadian youth.
- Trial name
- NCT01655615
- Testing
- Preventure programme
- Where
- Canada
- Volunteers
- 3,900 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use Disorder
Smoking Cessation Treatment for Substance Use Dependents
The present research project aims to develop an innovative and empirically validated intervention protocol for smoking cessation among patients with substance use disorders (SUDs).
- Trial name
- NCT03551704
- Testing
- CBT + EFT, CBT + EFT + CM
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Oviedo
Alcohol Use Disorder, Couples
Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder
This project will develop and pilot test a new smartphone-based system for AUD patients, their partners, and clinicians called PartnerCHESS. PartnerCHESS will integrate key features of ABCT and A-CHESS.
- Conditions
- Alcohol Use Disorder, Couples, Behavior, Addictive
- Trial name
- NCT04059549
- Testing
- PartnerCHESS, A-CHESS
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Wisconsin, Madison
HIV Infection, Alcohol Use
Alcohol's Impact on Inflammatory Markers in HIV Disease - Russia ARCH Cohort
The purpose of this study is to assess the longitudinal association between alcohol consumption and biomarkers of microbial translocation (sCD14) and inflammation/altered coagulation (IL-6/D-dimer); to establish a cohort of…
- Trial name
- NCT01614626
- Where
- Russia
- Volunteers
- 351 people
- Sponsor
- Boston Medical Center
Alcohol Use Disorder
Addiction Risk: Psychoeducational Intervention to Change Risk Perception Among Alcohol Patients in Residential Treatment
Based on previous research (Odenwald \& Semrau, 2012) the investigators know that psychoeducation on comorbid mental disorders during residential alcohol detoxification can improve subsequent treatment utilization.
- Trial name
- NCT03339674
- Testing
- Psychoeducational Group Intervention on Alcohol Drinking Related to Stress, Cognitive Training
- Where
- Germany
- Volunteers
- 144 people
- Sponsor
- University of Konstanz
Alcohol Abstinence
Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)
Guanfacine may preferentially reduce craving and improve cognitive control in women with Alcohol Use Disorder (AUD), compared to men.
- Trial name
- NCT03137082
- Testing
- Guanfacine XR 3mgs/daily
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stony Brook University
Addiction, Alcohol
Recovery of Individuals With Alcohol Use Disorders Based on Roy Adaptation Model
Abstract Aim: This study aimed to determine the effect of individualized nursing interventions based on the Roy Adaptation Model on the recovery of alcohol addicts.
- Trial name
- NCT06114316
- Testing
- individualized nursing interventions based on the Roy Adaptation Model /experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Izmir Katip Celebi University
Alcohol-Related Disorders, Alcohol Use Disorders
Adaptive Interventions for Problem Drinkers
The purpose of this study is to understand how certain interventions help people reduce or quit their drinking and how certain interventions may help best at certain points in time in the change process.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT02511808
- Testing
- Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Northwell Health
Alcohol Use Disorder (AUD)
Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery
The overarching goal of this study is to develop and examine the feasibility of a music-listening intervention that can be deployed in "real time" to regulate emotions and reduce momentary stress among young adults within the…
- Trial name
- CalmiFy (NCT07052318)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington State University
Smoking, Nicotine Dependence
Alcohol Counseling for Telephone Quitline Callers
The goal of this study is to train phone counselors working for the New York (NY) State Smokers' Quitline to advise callers who drink at hazardous levels to limit or abstain from alcohol use to determine whether this improves…
- Conditions
- Smoking, Nicotine Dependence, Alcohol Dependence
- Trial name
- NCT01120080
- Testing
- Practical Counseling, Alcohol Intervention Counseling
- Where
- United States
- Volunteers
- 1,948 people
- Sponsor
- Yale University
Alcoholism
High Dose Vitamin B1 to Reduce Abusive Alcohol Use
B1AS tests the hypothesis that increased vitamin B1 (thiamine) intake can repair brain systems damaged by alcohol and help people with alcohol problems control their alcohol use.
- Trial name
- B1AS (NCT00680121)
- Testing
- Benfotiamine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas
Alcohol Dependence
Transcranial Magnetic Stimulation in Alcohol Use Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) of the dorsolateral prefrontal cortex may affect neuro-adaptations associated with alcohol use disorder (AUD), potentially influencing craving and alcohol intake.
- Trial name
- NCT02862093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Catholic University of the Sacred Heart