Clinical trials: Alcohol Use Disorder (AUD)
AUD
Phase II Clinical Study on the Efficacy and Safety of Naltrexone Implant in Patients With Alcohol Use Disorder
This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial. The study plans to enroll 210 adult patients with alcohol use disorder.
- Trial name
- NCT07333638
- Testing
- low-dose group (naltrexone implant 0.9 g + general supportive psychological counseling), high-dose group (naltrexone implant 1.5 g + general supportive psychological counseling)
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Shenzhen Sciencare Medical Industries Co., Ltd.
Alcohol Use Disorder (AUD)
A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder
TMP-301 has been shown in preclinical models to reduce consumption of alcohol and other addictive substances. It has been tested in healthy subjects and has been found to be safe and tolerated at doses predicted to be efficacious…
- Trial name
- LIBERATE-A (NCT06648655)
- Testing
- TMP-301
- Where
- 14 sites in United States
- Volunteers
- 110 people
- Sponsor
- Tempero Bio, Inc.
Alcohol Use Disorder (AUD)
Study of DCR-AUD in Healthy Volunteers
DCR-AUD will be evaluated for safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy volunteers.
- Trial name
- NCT05021640
- Testing
- DCR-AUD
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company