Clinical trials: Alcohol Withdrawal Syndrome
Alcohol Withdrawal Syndrome
Clinical Quality Improvement of Benzodiazepine-Resistant Alcohol Withdrawal Syndrome
The overarching goal of this project is to improve the clinical quality of patients with Benzodiazepine-resistant alcohol withdrawal syndrome.
- Trial name
- NCT01652326
- Testing
- Diazepam
- Where
- United States
- Volunteers
- 792 people
- Sponsor
- University of Pittsburgh
Alcohol Withdrawal
Gabapentin vs Chlordiazepoxide for Ambulatory Alcohol Withdrawal
A randomized, double-blind controlled trial comparing treatment outcomes between chlordiazepoxide, or gabapentin to treat alcohol withdrawal syndrome in alcohol dependent veteran subjects.
- Trial name
- NCT01573052
- Testing
- Chlordiazepoxide, Gabapentin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- VA Salt Lake City Health Care System
Alcohol Withdrawal
Liver Stiffness Measurement in Alcohol-dependent Subjects in Relation to Abstinence After Withdrawal
This study is complementary to the main study "Brain Derived Neurotrophic Factor Serum Levels Evolution During the Six Months After Alcohol Withdrawal " NCT01491347.
- Trial name
- NCT02202148
- Where
- France
- Volunteers
- 195 people
- Sponsor
- Centre Hospitalier Esquirol
Alcoholics
Alcohol Abuse or Alcohol Withdrawal: Risk of Latent Scurvy
Scurvy, or latent scurvy, may be underestimated in developed countries, but continue to be described, often as case report. Little is known about the prevalence of vitamin C deficiency in a specific population as withdrawal…
- Trial name
- NCT03467022
- Testing
- Vitamin C
- Volunteers
- 47 people
- Sponsor
- SCP Battistelli
Alcohol Use Disorder, Alcohol Withdrawal
Does a Ketogenic Dietary Supplement Reduce Alcohol Withdrawal Symptoms in Humans?
A ketogenic diet (KD) is high in fat and low in carbohydrates and induces ketosis. KD is an approved non-pharmacological therapy for drug-resistant child epilepsy.
- Conditions
- Alcohol Use Disorder, Alcohol Withdrawal, Ketosis
- Trial name
- KME (NCT03878225)
- Testing
- H.V.M.N. Ketone Ester
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Alcoholism, Alcohol Withdrawal
Preventing Alcohol Withdrawal With Oral Baclofen
The purpose of this study is determine if the medication baclofen can prevent the symptoms of Alcohol Withdrawal Syndrome (AWS) in hospitalized patients who may be at risk for AWS.
- Trial name
- BACLOFEN III (NCT01937364)
- Testing
- Baclofen
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Essentia Health
Alcohol Withdrawal
Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal
This study is designed to evaluate the addition of ketamine to dexmedetomidine as adjunctive therapies of severe alcohol withdrawal in medical ICU patients.
- Trial name
- NCT02823977
- Testing
- Ketamine, Dexmedetomidine, Normal saline
- Where
- United States
- Sponsor
- University of Colorado, Denver
Alcohol Withdrawal, Anxiety
Comparison of the Effect on Anxiety of Combining Hypnosis and Aromatherapy Through Olfactory Anchoring Versus Standard Care in Patients Undergoing Alcohol Withdrawal
According to a meta-analysis published in 2019, hypnosis has demonstrated positive effects in the treatment of certain mental illnesses, particularly anxiety.
- Trial name
- ASHA (NCT07444255)
- Testing
- Usual treatment, Experimental treatment
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Alcohol Drinking, Alcohol Intoxication
Family Based Prevention of Alcohol and Risky Sex for Older Teens
An online, interactive web-based program for older teens and their parents is designed to address teen alcohol use and teen relationships.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders
- Trial name
- NCT03521115
- Testing
- Smart Choices 4 Teens
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Alcohol Use Disorder
Psychosocial Intervention For Domiciliary Alcohol Detoxification
Alcohol Use Disorders (AUD) form a major public health issue in India. In a densely populated country with limited mental health resources, it is challenging to treat those with AUD appropriately.
- Trial name
- NCT05563740
- Testing
- Psychosocial
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Dr Sneha B Suresh
Alcohol Withdrawal State
Dexmedetomidine Addition to Benzodiazepines for Patients With Alcohol Withdrawal State in the ICU
The objective of this randomized controlled study was to evaluate whether DEX addition to benzodiazepine therapy is effective and safe for AWS patients in the intensive care unit (ICU).
- Trial name
- NCT02496650
- Testing
- Dexmedetomidine
- Volunteers
- 70 people
- Sponsor
- Bogomolets National Medical University
Alcohol Withdrawal Syndrome(AWS)
Comparing the Treatment of Alcohol Withdrawal Syndrome Using Gabapentin Versus Lorazepam
The purpose of this study was to evaluate if the medication Gabapentin, which is not approved for the treatment of alcohol withdrawal, is effective in the treatment of alcohol withdrawal syndrome compared to treatment with…
- Trial name
- NCT00229125
- Testing
- Gabapentin, Lorazepam
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Withdrawal, Alcohol Dependence
Oxytocin Treatment of Alcohol Dependence
This study will test in individuals who have alcohol dependence (alcohol addiction) the hypotheses 1) that intranasal oxytocin treatment will decrease withdrawal symptoms during medical detoxification and 2) that intranasal…
- Trial name
- OT-ETOH2 (NCT02275611)
- Testing
- intranasal oxytocin spray
- Volunteers
- 13 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Withdrawal Syndrome
Assessment of Energetic Resonance by Cutaneous Stimulation on Withdrawal Alcohol Symptoms.
The purpose of RESC study is to assess the efficacy of Energetic Resonance by Cutaneous Stimulation on alcohol withdrawal symptoms measured by CUSHMAN score and in a second time to measure the benzodiazepine amount prescribed…
- Trial name
- RESC (NCT02146716)
- Testing
- Energetic Resonance by Cutaneous Stimulation
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Alcohol Withdrawal
Prazosin for Alcohol Use Disorder With Withdrawal Symptoms
This is a Phase 2 single site randomized clinical trial (RCT) to be supported by a new NIH-NIAAA grant, R01-AA029113-01, to assess the efficacy of Prazosin (16mg/day) versus Placebo over a 12 week treatment period, followed by a…
- Trial name
- NCT04793685
- Testing
- Prazosin, 12-Step Facilitation with Relapse Prevention and Contingency Management
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Yale University
Alcohol Withdrawal, Lactic Acidosis
Alcohol: Thiamine and or Magnesium 1
Patients who suffer Alcohol Use Disorder (AUD) have a 30-80% incidence of thiamine deficiency causing Wernicke's Encephalopathy (WE).
- Conditions
- Alcohol Withdrawal, Lactic Acidosis, Vitamin B1 Deficiency, Magnesium Deficiency
- Trial name
- AToM1 (NCT03466528)
- Testing
- Magnesium Sulfate, Pabrinex
- Where
- United Kingdom
- Volunteers
- 127 people
- Sponsor
- Glasgow Royal Infirmary
Alcohol Withdrawal Syndrome, Alcohol Dependence
Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome
Benzodiazepines (BDZs) are the gold standard in the treatment of alcohol withdrawal syndrome (AWS). Gamma-Hydroxybutyric acid also known as sodium oxybate (SMO) has been tested as a treatment for AWS with encouraging results.
- Trial name
- GATE I (NCT02090504)
- Testing
- Sodium Oxybate (SMO), Oxazepam
- Where
- 3 sites in Austria, Italy
- Volunteers
- 127 people
- Sponsor
- Catholic University of the Sacred Heart
Alcohol Withdrawal
Use of tAN® in Alcohol Withdrawal Management
This research study is being conducted to learn if Transcutaneous Auricular Neurostimulation (tAN®) may be effective in treating alcohol withdrawal syndrome.
- Trial name
- NCT06771037
- Testing
- Transcutaneous Auricular Neurostimulation (tAN)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Erin Takemoto
Topiramate, Lamotrigine
Antiglutamate Anticonvulsants in the Treatment of Alcohol Withdrawal Syndrome
The study is aimed to evaluate the efficacy of antiglutamate anticonvulsants (topiramate, lamotrigine, and memantine) in the treatment of alcohol withdrawal syndrome
- Conditions
- Topiramate, Lamotrigine, Memnatine, Diazepam
- Trial name
- NCT00241995
- Testing
- Anticonvulsants
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Petersburg State Pavlov Medical University
Alcohol Withdrawal Delirium
Treating Alcohol Withdrawal With Oral Baclofen
The purpose of this study is determine if subjects with alcohol withdrawal who receive oral baclofen, plus standard benzodiazepine therapy, will experience less severe withdrawal symptoms than those who receive placebo plus…
- Trial name
- NCT00597701
- Testing
- Baclofen, Lorazepam
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Essentia Health