Clinical trials: Alcohol-Related Injury
Anxiety Depression, Alcohol Abuse
CBD Oil for Reducing Emotional Impact of COVID-19
Our purpose is to conduct a 4-arm placebo-controlled clinical trial to investigate the relative clinical efficacy of 300 mg. of pure hemp-derived CBD isolate, 300 mg. of full spectrum CBD oil, 300 mg.
- Conditions
- Anxiety Depression, Alcohol Abuse, Substance Abuse, Anger
- Trial name
- CBDOIL (NCT04603781)
- Testing
- CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
The overall objective of the proposed study is to determine if Dexmedetomidine HCl (BXCL501) is safe for treatment of alcohol use disorder (AUD) with comorbid posttraumatic stress disorder (PTSD) in an outpatient setting and also…
- Trial name
- NCT06335407
- Testing
- Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Alcohol Use Disorder, Alcohol-Related Injury
Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon
Brief Summary Alcohol use is a major contributor to injury burden in Cameroon, particularly among trauma patients presenting to emergency departments.
- Conditions
- Alcohol Use Disorder, Alcohol-Related Injury, Trauma
- Trial name
- NCT07677449
- Testing
- Cameroon-Adapted SBIRT, Usual Care
- Where
- Cameroon
- Volunteers
- 690 people
- Sponsor
- University of Buea
Alcoholism, Anxiety Disorders
Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety
Alcohol use disorders (AUDs) are a major problem facing our society. Their treatment is complex, and involves multiple behavioral and pharmacotherapy interventions.
- Conditions
- Alcoholism, Anxiety Disorders, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00352469
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Creighton University
Alcohol Abuse, Alcohol Dependence
Enhanced Motivational Interviewing With Alcohol Positive Trauma Patients
The primary goal of this study is to test the efficacy of a brief intervention that includes the patient and a significant other, relative to an intervention including the patient only, for reducing alcohol use and…
- Trial name
- NCT00280488
- Testing
- Motivational Interview, Assessment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Brown University
Alcohol Use Disorder, Injury Traumatic
PRACT to Investigate Controlling Alcohol Related Harms in a Low-Income Setting; Emergency Department BIs in Tanzania
Alcohol use is rapidly increasing in low- and middle-income countries, where it is inexpensive, readily available, poorly regulated, and there are few resources devoted to promoting safe alcohol use.
- Conditions
- Alcohol Use Disorder, Injury Traumatic, Trauma
- Trial name
- PRACT (NCT04535011)
- Testing
- PPKAY (brief intervention), Standard Booster, Personalized Booster
- Where
- Tanzania
- Volunteers
- 674 people
- Sponsor
- Duke University
Stress Disorders, Post-Traumatic, Intimate Partner Violence
Addressing the Health Concerns of VA Women With Sexual Trauma
Lifetime sexual trauma (ST) (i.e., behaviors that range from unwanted sexual touching to attempted or completed rape) is a significant social and public health problem among women Veterans.
- Conditions
- Stress Disorders, Post-Traumatic, Intimate Partner Violence, Alcohol-Related Disorders
- Trial name
- SHE (NCT02957747)
- Testing
- SHE
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VISN 17 Center of Excellence
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD)
This treatment intervention trial is designed for men and women with substance dependence and comorbid Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01365247
- Testing
- Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure, Relapse Prevention Treatment, Active Monitoring Control Group
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- The City College of New York
Posttraumatic Stress Disorder, Depression
Trauma Survivors Outcomes and Support Study IV
After traumatic injuries some people have difficulty returning to the routine of their everyday activities and may experience physical and emotional pain.
- Conditions
- Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury
- Trial name
- TSOS IV (NCT01625416)
- Testing
- Stepped Care Management
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Washington
Alcohol Drinking, Alcohol Use Disorder
Effect of Theta Burst Stimulation on Alcohol Cue Reactivity
Alcohol Use Disorder (AUD) is prevalent, devastating, and difficult to treat. The intransigence of AUD is readily apparent in the Trauma Unit of Wake Forest University Baptist Hospital, wherein 23% of trauma related admissions…
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence
- Trial name
- NCT04223154
- Testing
- Real iTBS to the dlPFC
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences