Clinical trials: Alcohol-dependence
Alcohol Use Disorder
Pilot Human Laboratory Study of Alcohol Approach Bias Modification (AABM) for Alcohol Use Disorder (AUD)
The overall goal of the proposed project is to improve the treatment of individuals with Alcohol Use Disorder (AUD). We will conduct a pilot feasibility trial of Approach Bias Modification (AABM) training of heavy-drinking…
- Trial name
- ADP + AABM (NCT03898323)
- Testing
- Alcohol Approach Bias Modification
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Use Disorders
Therapeutic Alliances in Alcoholism Treatment
This project is studying the role of the therapeutic alliance between the therapist and patient in the outpatient treatment of persons with alcohol use disorders.
- Trial name
- NCT01689103
- Testing
- Cognitive-behavioral treatment
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- State University of New York at Buffalo
Potential Treatment for Alcohol Dependence-Alcohol Interaction
Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)
The purpose of this clinical study is to assess pharmacokinetic interactions between ethanol (EtOH) and PT150 (900 mg qd) in non-treatment-seeking alcohol-experienced volunteers-(to include military service members, veterans…
- Trial name
- NCT04331288
- Testing
- PT150, Beverage
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pop Test Oncology LLC
Alcohol Dependence
Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Alcohol Dependence
Alcohol dependence is one of most common substance dependence, which brings great burden on health worldwide. Alcohol dependence may lead to many serious diseases or consequences including cancer, cardiovascular diseases and…
- Trial name
- TAD (NCT03910686)
- Testing
- Transcranial magnetic stimulation and cognitive behavioral therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Alcohol Abuse, Obesity
Project ACTIVE a Clinical Intervention
This is a clinical Randomized Controlled Trial where the study personnel will run a personalized prevention clinic with patients in attempts to improve their preventive health outcomes and compare their health outcomes with a…
- Trial name
- NCT04211883
- Testing
- ACTIVE intervention
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alcohol Use Disorder, Opioid Use Disorder
TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)
The study aims to explore the potential of Transcranial Magnetic Stimulation (TMS), particularly Theta Burst Stimulation (TBS), as an adjunctive treatment to enhance recovery outcomes (consumption and craving; withdrawal…
- Trial name
- TMS4OUDAUD (NCT07171359)
- Testing
- TMS Low-Dose, TMS High-Dose
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington State University
HIV/AIDS, Dysglycemia
Alcohol & Metabolic Comorbidities in PLWHA: Evidence Driven Interventions
Cross-sectional and prospective studies are proposed to test the prediction that a higher proportion of HIV+ individuals with hazardous alcohol drinking with subclinical fasting dysglycemia will present with impaired oral glucose…
- Conditions
- HIV/AIDS, Dysglycemia, Alcohol Use Disorder
- Trial name
- ALIVE-Ex (NCT03299205)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Alcohol Use Disorder
Neural and Hormonal Influences on Sex Differences in Risk for AUD
The sex gap in alcohol consumption is closing rapidly, due to alarming increases among women. From 2002-2013, Alcohol Use Disorder (AUD) increased 84% for women, compared to 35% for men.
- Trial name
- NCT04929288
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jessica Weafer
Alcoholism
Clinical Study of TripleA for Treatment of Alcohol Addiction in Outpatient Care
The primary objective is to investigate differences in the alcohol consumption pattern between alcohol addicts receiving conventional treatment and those who receive a combination of conventional treatment and TripleA.
- Trial name
- NCT03195894
- Testing
- TripleA
- Volunteers
- 115 people
- Sponsor
- Kontigo Care AB
HIV-infection/Aids, Intimate Partner Violence
Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention
This study will develop and pilot test a couples-based intervention to help adolescent girls and young women living with HIV (WLHIV (15-24 years) living in Uganda access HIV care and improve the outcomes of their HIV treatment by…
- Conditions
- HIV-infection/Aids, Intimate Partner Violence, Domestic Violence, Alcohol Use Disorder
- Trial name
- NCT05947539
- Testing
- Kisoboka Mukwano ("It is possible, my love!") Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 80 people
- Sponsor
- Arizona State University
Alcohol Use Disorder (AUD)
Non-invasive Brain Stimulation of the Prefrontal Cortex in Substance Use Disorders
Every year, alcohol causes 3 million deaths worldwide. Even though a lot of treatments already exist, many of them are characterized by a high percentage of drop-out or relapse.
- Trial name
- NIBSSUD (NCT05471154)
- Testing
- High Definition transcranial direct current stimulation (HD-tDCS)
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Alcohol Use Disorder
Quality of Life in Patients With Alcohol Use Disorder
The primary purpose of this study is to investigate the factors associated with quality of life of patients with alcohol use disorder (AUD) undergoing a detoxification program (cross-sectional analysis).
- Trial name
- QUALIFACT (NCT04748822)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Hôpital le Vinatier
Alcohol Use Disorder
Neurofeedback Training of Metacognition in Subjects With Alcohol Use Disorder. Disorder Induces Neural Modifications: an Event-related Potentials Study
Addressing cognitive deficits in alcohol use disorder (AUD) supports recovery. Impaired metacognitive functioning in AUD causes compromised recognition of the interoceptive state leading to the maintenance of alcohol abuse…
- Trial name
- NCT05913518
- Testing
- Neurofeedback active
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Brugmann University Hospital
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency
The Whole Day First Grade Program
This five-year prevention services application is concerned with preventing substance abuse, comorbid mental and behavioral disorders, and school failure.
- Conditions
- Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco
- Trial name
- NCT00257088
- Testing
- whole day first grade program
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- American Institutes for Research
Addiction, Addiction Disorders
Can Selfcompassion Training Reduce Alcohol Consumption in Patients With Alcohol Use Disosrder ?
The objective of this interventional study is to evaluate the effectiveness of the Mindful Self-Compassion (MSC) program in reducing alcohol consumption in a population of individuals with Alcohol Use Disorder (AUD), six months…
- Conditions
- Addiction, Addiction Disorders, Alcohol Use Disorders, Alcohol Dependence
- Trial name
- COMPAL (NCT07131124)
- Testing
- Mindful Self-Compassion program, Treatment As Usual (TAU) program
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Alcohol Withdrawal Syndrome
MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA)
This study examine the efficacy of oral magnesium supplementation as an adjuvant therapy for decreasing intensity of alcohol withdrawal symptoms among inpatients requiring pharmacological treatment of their AWS.
- Trial name
- MAGMA (NCT03033823)
- Testing
- Magnesium
- Where
- 11 sites in France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Abuse, Alcohol Addiction
Internet-Based Relapse Prevention vs Face to Face Therapy at an Employee Assistance Program
Objectives: This study will evaluate the efficacy of internet-based relapse prevention with therapist support, as compared to face-to-face therapy at an employee assistance program.
- Trial name
- FoBeMA (NCT02014779)
- Testing
- eChange, Face-to-face therapy
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Karolinska Institutet
Alcoholism
Ketamine/Placebo Family History Positive Study
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00588952
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine
The primary objectives of this study are twofold. The first primary objective is to evaluate the feasibility, acceptability, and tolerability of atomoxetine (40 mg/day for 3 days then 80 mg/day thereafter) as compared to placebo…
- Trial name
- NCT04565288
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Brown University
Drug Dependence
Brain Function in Response to Motivational Stimuli
This study seeks more information about the biology of substance dependency by exploring the brain areas involved in feeling positive and negative emotions.
- Trial name
- NCT00047866
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)