Clinical trials: Alcohol-induced Disorders
Depression, Alcohol Abuse
Therapy for Undergraduate College Students Who Binge Drink and Are Depressed
The purpose of this study is to investigate the effectiveness of 2 different therapy courses for undergraduate college students who binge drink and experience depressive symptoms.
- Trial name
- TREADS (NCT01632319)
- Testing
- Combined Motivational Interviewing and Cognitive Behavioral Therapy, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Massachusetts General Hospital
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Alcohol Use Disorder (AUD)
Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder
Alcohol use disorder (AUD) is the second highest preventable cause of death in France. Only 3% of patients are prescribed approved drugs for reducing alcohol consumption or maintenance of abstinence.
- Trial name
- MBRP (NCT04598399)
- Testing
- Mindfulness Based Relapse Prevention, Relaxation/ meditation
- Where
- 7 sites in France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Alcohol Use Disorder
Clinical Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder (AUD)
This study is a randomized controlled trial of oral semaglutide among treatment-seeking individuals with AUD. The investigators will randomly assign 50 participants to receive semaglutide (titrated to 7 milligrams (mg) per day)…
- Trial name
- NCT05892432
- Testing
- Semaglutide 3 MG [Rybelsus], Semaglutide 7 MG [Rybelsus]
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Alcoholism, Schizophrenia
Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism
This placebo-controlled study is designed to evaluate the efficacy of glycine, an agonist of the glycine-B co-agonist site of the NMDA receptor, on alcohol consumption and craving as well as negative symptoms in schizophrenia.
- Trial name
- NCT00338598
- Testing
- Glycine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Alcohol Use, Unspecified, Substance Use
ANCHORS Alcohol & Sexual Health Study: UH3 Project
80 young adult men will complete an initial survey and receive 1 of 2 types of alcohol and sexual health education and information to encourage prevention of alcohol-related problems, HIV and other sexually transmitted infections…
- Conditions
- Alcohol Use, Unspecified, Substance Use, Sex Behavior
- Trial name
- NCT04331704
- Testing
- PrEP acronym (pre-exposure prophylaxis), Initial Web Survey, Interactive Voice Response (IVR) monitoring
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Drinking, Alcoholism
Digital Human-Based Brief Interventions for Harmful Alcohol Use: The PAHOLA Project
Alcohol use disorders are among the most prevalent mental disorders in Canada; however, due to numerous barriers, including fear of treatment, privacy concerns, stigma, time conflicts, and lack of availability of treatment, less…
- Trial name
- NCT05906979
- Testing
- PAHOLA (digital health assistant), Standard information on alcohol use and health
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Alcohol Dependence
Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence
This study will test the safety and efficacy of the PROMETA® Treatment Protocol (which includes the benzodiazepine antagonist flumazenil) in reversing the neurocognitive impairment and this in turn will lead to improved ability…
- Trial name
- NCT00570388
- Testing
- Prometa Treatment Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Institute of Addiction Medicine
Alcohol Addiction, Mouth Diseases
Testing Interventions to Reduce Alcohol Consumption Among Outpatients in a Dental Setting
The investigators wish to investigate the feasibility of using a web based drinking app (www.drinksmeter.com) to reduce alcohol consumption among patients attending an outpatient clinic in a dental setting.
- Trial name
- NCT02374905
- Testing
- Drinksmeter, Brief Advice of Alcohol Use
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Sepsis, Alcoholism
Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis
Patients with alcohol use disorders are often cared for in the intensive care unit (ICU). We estimate that close to half of the patients we care for in our ICU have alcohol use disorders.
- Trial name
- NCT00615862
- Testing
- Observational study; no interventions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Alcohol Dependence
Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Alcohol Dependence
Alcohol dependence is one of most common substance dependence, which brings great burden on health worldwide. Alcohol dependence may lead to many serious diseases or consequences including cancer, cardiovascular diseases and…
- Trial name
- TAD (NCT03910686)
- Testing
- Transcranial magnetic stimulation and cognitive behavioral therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Alcohol-related Disorders, Drinking and Driving
Evaluation of an School-based Alcohol Prevention Program for Middle School Students
The purpose of this research is to create and evaluate the efficacy of an exciting (fun to use), and potentially disseminable computer-based prevention program, Click City®: Alcohol, for use by 7th graders with a booster in 8th…
- Conditions
- Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
- Trial name
- AlcoholINET (NCT01847183)
- Testing
- Click City®: Alcohol
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Oregon Research Institute
Alcoholism, Stress
Alcohol and Gender Effects on Stress Circuit Function
The purpose of this study is to look at the stress hormone response to medication-induced stress and a placebo (an inactive compound) in non-drinking, recovering male and female alcoholics, with a specific emphasis on the…
- Conditions
- Alcoholism, Stress, Alcohol Dependence
- Trial name
- NCT00226694
- Testing
- Citalopram
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Alcoholic Liver Disease
Herbal Supplements for Improvement of Liver Function in Participants With Alcoholic Liver Disease
Alcoholic liver disease represents the major health issues and it ranges from simple steatosis to cirrhosis. There is a paucity of data to support the allopathic intervention among these group of patients.
- Trial name
- NCT03503708
- Testing
- Livitol-70
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Composite Interceptive Med Science
Alcohol Dependence
Biomarkers to Measure Treatment Response for Alcohol Dependence
The purpose of the research study of the K23 award is to develop a blood test that can check how much alcohol a person has consumed in the past few days.
- Trial name
- NCT02315885
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Alcohol Use Disorder
Emotional Attention Bias Modification and Targeted Memory Reactivation in Alcohol Use Disorder
Through this protocol, researchers examine whether Targeted Memory Reactivation (TMR), a technique used to enhance memory, can augment the control of craving levels in patients with Alcohol Use Disorder by enhancing positive…
- Trial name
- NCT06457113
- Testing
- Emotional Attention Bias Modification and Targeted memory reactivation during REM sleep, Emotional Attention Bias Modification
- Volunteers
- 74 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Use Disorder
Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder
Research about patients with alcohol use disorder has shown that task-related brain activation patterns as well as resting-state connectivity (measured with functional magnetic resonance imaging) change with clinical parameters…
- Trial name
- NIQA (NCT05843435)
- Testing
- Go-Nogo-task during functional magnetic resonance imaging, Resting-state functional magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcohol Dependence, Stress Disorders, Post-Traumatic
Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
Prazosin is an alpha-1 adrenergic receptor antagonist that has been used successfully in the treatment of trauma nightmares and sleep disturbance in combat veterans with PTSD, and alcohol dependence.
- Trial name
- NCT00744055
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Yale University
Alcoholism
Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder
This is a pilot study designed to evaluate the safety, tolerability of Topiramate (TPM) + N-Acetyl Cysteine (NAC) in combination versus Topiramate (TPM) + placebo for the treatment of alcohol use disorder (AUD).
- Trial name
- NCT03120468
- Testing
- Topiramate and N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Nassima Ait-Daoud Tiouririne
Alcohol Dependence
Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence
Alcohol dependence (AD) is a prevalent and burdensome clinical condition with high relapse rates. A central risk factor for relapse is craving for alcohol, which can be evoked by both real-world and virtual cues in immersive…
- Trial name
- NCT07388693
- Testing
- VR Cue-Exposure Including Olfactory Stimuli
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
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