Clinical trials: Alcohol-induced Disorders
HIV-infection/Aids, Intimate Partner Violence
Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention
This study will develop and pilot test a couples-based intervention to help adolescent girls and young women living with HIV (WLHIV (15-24 years) living in Uganda access HIV care and improve the outcomes of their HIV treatment by…
- Conditions
- HIV-infection/Aids, Intimate Partner Violence, Domestic Violence, Alcohol Use Disorder
- Trial name
- NCT05947539
- Testing
- Kisoboka Mukwano ("It is possible, my love!") Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 80 people
- Sponsor
- Arizona State University
Cirrhosis, Cirrhosis, Liver
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
This is a double-blind, phase 2 study to evaluate safety and efficacy of rosuvastatin in comparison to placebo after 2 years in patients with compensated cirrhosis.
- Conditions
- Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B
- Trial name
- LCN RESCU (NCT05832229)
- Testing
- Rosuvastatin
- Where
- 13 sites in United States
- Volunteers
- 260 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy Volunteers, Alcohol Drinking Related Problems
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
Background: Problem drinking affects nearly half the people who drink alcohol. Drinking alcohol affects a person's social behavior and brain structure, but researchers don't have a good understanding of how.
- Conditions
- Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
- Trial name
- NCT03535129
- Testing
- Real time fMRI neurofeedback
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alcohol Use Disorder (AUD)
Non-invasive Brain Stimulation of the Prefrontal Cortex in Substance Use Disorders
Every year, alcohol causes 3 million deaths worldwide. Even though a lot of treatments already exist, many of them are characterized by a high percentage of drop-out or relapse.
- Trial name
- NIBSSUD (NCT05471154)
- Testing
- High Definition transcranial direct current stimulation (HD-tDCS)
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Alcohol Use Disorder
Quality of Life in Patients With Alcohol Use Disorder
The primary purpose of this study is to investigate the factors associated with quality of life of patients with alcohol use disorder (AUD) undergoing a detoxification program (cross-sectional analysis).
- Trial name
- QUALIFACT (NCT04748822)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Hôpital le Vinatier
Alcoholic Hepatitis
Bovine Colostrum In The Treatment Of Severe Alcohol-Associated Hepatitis
Severe Alcohol-associated hepatitis, is associated with significant morbidity and mortality.1,2 Of the various treatment modalities evaluated for treatment of Severe Alcoholic hepatitis, corticosteroids have been the most…
- Trial name
- BASH (NCT07898761)
- Testing
- Bovine Colostrum Preparation
- Where
- India
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Dayanand Medical College and Hospital
Alcoholic Intoxication
Emergency Department (ED) Triage of Alcohol Abuse
Retrospective study of adult patients (> 16 y) admitted to Geneva University Hospitals with alcohol abuse. Triage criteria will be reviewed. Patients characteristics and patient flow in the ED will be described.
- Trial name
- NCT02449772
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 775 people
- Sponsor
- University Hospital, Geneva
Liver Failure, Hepatitis B
RCT Study on Granulocyte Colony-stimulating Factor(G-CSF) Treatment of Hepatic Failure
This study evaluates the Granulocyte colony-stimulating factor (G-CSF) in the treatment of Acute on Chronic Liver Failure in adult.
- Conditions
- Liver Failure, Hepatitis B, Alcoholic Liver Disease
- Trial name
- NCT02331745
- Testing
- Granulocyte colony-stimulating factor, standard treatment
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing 302 Hospital
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder
Neurofeedback Training of Metacognition in Subjects With Alcohol Use Disorder. Disorder Induces Neural Modifications: an Event-related Potentials Study
Addressing cognitive deficits in alcohol use disorder (AUD) supports recovery. Impaired metacognitive functioning in AUD causes compromised recognition of the interoceptive state leading to the maintenance of alcohol abuse…
- Trial name
- NCT05913518
- Testing
- Neurofeedback active
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Brugmann University Hospital
HIV Infection, Alcohol Consumption
Boston ARCH 4F Intervention to Reduce Fall Risk in People With HIV and Alcohol Use
This study is being conducted to assess the acceptability and feasibility of a randomized trial of a 10 week virtual intervention to reduce fall risk in people with HIV who consume alcohol.
- Conditions
- HIV Infection, Alcohol Consumption, Falls, Accidental, Falls
- Trial name
- NCT04804579
- Testing
- Fall Prevention Intervention
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Boston University
Chronic Pain, Post-traumatic Stress Disorder
The Norwegian Addiction, Pain and Trauma Study
In populations with substance use disorders (SUD), there is a high prevalence of chronic pain with various underlying causes. Chronic pain can complicate the treatment of SUD and lead to poorer treatment outcomes.
- Conditions
- Chronic Pain, Post-traumatic Stress Disorder, Substance Use Disorders
- Trial name
- NOR-APT (NCT04908410)
- Where
- 4 sites in Norway
- Volunteers
- 1,650 people
- Sponsor
- University Hospital, Akershus
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency
The Whole Day First Grade Program
This five-year prevention services application is concerned with preventing substance abuse, comorbid mental and behavioral disorders, and school failure.
- Conditions
- Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco
- Trial name
- NCT00257088
- Testing
- whole day first grade program
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- American Institutes for Research
Addiction, Addiction Disorders
Can Selfcompassion Training Reduce Alcohol Consumption in Patients With Alcohol Use Disosrder ?
The objective of this interventional study is to evaluate the effectiveness of the Mindful Self-Compassion (MSC) program in reducing alcohol consumption in a population of individuals with Alcohol Use Disorder (AUD), six months…
- Conditions
- Addiction, Addiction Disorders, Alcohol Use Disorders, Alcohol Dependence
- Trial name
- COMPAL (NCT07131124)
- Testing
- Mindful Self-Compassion program, Treatment As Usual (TAU) program
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Alcohol Withdrawal Syndrome
MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA)
This study examine the efficacy of oral magnesium supplementation as an adjuvant therapy for decreasing intensity of alcohol withdrawal symptoms among inpatients requiring pharmacological treatment of their AWS.
- Trial name
- MAGMA (NCT03033823)
- Testing
- Magnesium
- Where
- 11 sites in France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Abuse, Alcohol Addiction
Internet-Based Relapse Prevention vs Face to Face Therapy at an Employee Assistance Program
Objectives: This study will evaluate the efficacy of internet-based relapse prevention with therapist support, as compared to face-to-face therapy at an employee assistance program.
- Trial name
- FoBeMA (NCT02014779)
- Testing
- eChange, Face-to-face therapy
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Karolinska Institutet
Alcoholism
Ketamine/Placebo Family History Positive Study
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00588952
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine
The primary objectives of this study are twofold. The first primary objective is to evaluate the feasibility, acceptability, and tolerability of atomoxetine (40 mg/day for 3 days then 80 mg/day thereafter) as compared to placebo…
- Trial name
- NCT04565288
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Brown University
Drug Dependence
Brain Function in Response to Motivational Stimuli
This study seeks more information about the biology of substance dependency by exploring the brain areas involved in feeling positive and negative emotions.
- Trial name
- NCT00047866
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Suicide, Alcohol Abuse
Alcohol, Suicide and HIV Prevention for Teens in Mental Health Treatment
This study examines whether an integrated alcohol/substance abuse, suicide, and HIV prevention protocol is associated with lower onset and frequency of alcohol and other drug use, suicidal behavior, and high risk sexual behavior…
- Conditions
- Suicide, Alcohol Abuse, Drug Abuse, HIV
- Trial name
- NCT02228044
- Testing
- Prevention program
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- George Mason University
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