Clinical trials: Alcohol-induced Disorders
Alcohol; Use, Problem, Marijuana Usage
Project RAD: A Brief Intervention for Young Adult Alcohol or Marijuana Users
This is a pilot study of the feasibility, acceptability, and effectiveness of a brief, one-session intervention for a diverse sample of 44 young adults who report alcohol binge drinking or marijuana use in the past month.
- Trial name
- NCT03801096
- Testing
- Narrative Based Therapuetic Assessment (NbTa), Health Education Control Condition (HE)
- Volunteers
- 44 people
- Sponsor
- University of Houston
Psychiatric Disorder, Psychiatric Hospitalization
Advanced Chronic Liver Disease Screening by Transient Elstography in Patients Hospitalised in a Psychiatric Unit
Scares data exists concerning the prevalence of chronic liver diseases in people with psychiatric disorders. There are still many barriers to screening and linkage to care for patients having somatic illness.
- Conditions
- Psychiatric Disorder, Psychiatric Hospitalization, Advanced Chronic Liver Disease, Liver Fibrosis
- Trial name
- HEPSY (NCT05602870)
- Testing
- non invasive evaluation of liver fibrosis by transient elastography (Fibroscan ®)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Montpellier
Alcohol Abuse
Alcohol and Employment
The purpose of the study is to determine whether welfare-to-work schemes combined with alcohol treatment are more efficient than a welfare-to-work scheme alone, for unemployed citizens with alcohol problems.
- Trial name
- NCT01416103
- Testing
- Intervention group, Control group
- Where
- Denmark
- Volunteers
- 113 people
- Sponsor
- University of Southern Denmark
Alcoholic Hepatitis
Efficacy of Monotherapy vs Combination Therapy of Corticosteroids With GCSF in Severe Alcoholic Hepatitis Patients.
The patients of Severe Alcoholic Hepatitis (SAH) will be included in study based on inclusion and exclusion criteria. The patients will be then randomized in 3 groups for therapy.
- Trial name
- NCT04066179
- Testing
- Gcsf, Prednisolone
- Where
- India
- Volunteers
- 126 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency
The Whole Day First Grade Program
This five-year prevention services application is concerned with preventing substance abuse, comorbid mental and behavioral disorders, and school failure.
- Conditions
- Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco
- Trial name
- NCT00257088
- Testing
- whole day first grade program
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- American Institutes for Research
Substance Abuse, Criminal Behavior
Swift, Certain, and Fair: Reducing Recidivism and Improving Outcomes for Alcohol and Drug Users on State Parole
This research project will study the outcomes of medium- to high-risk parolees with a history of substance abuse in Alleghany County, Pennsylvania supervised under Swift-Certain-Fair parole.
- Trial name
- NCT03826420
- Testing
- SCF Supervision with Secure Confinement Sanctioning, SCF Supervision with Work Release Sanctioning, SCF Supervision with GPS Supervision Sanctioning
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Botec Analysis, LLC
Alcoholism
The Effects of Levetiracetam on Alcohol Dependent Subjects
This study will attempt to examine whether Levetiracetam (Keppra (TM)) can help people with alcohol dependence cut down on their alcohol consumption.
- Trial name
- NCT00325182
- Testing
- Levetiracetam, Historical controls
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University
Bulimia Nervosa, Alcohol Use Disorders
Examining Common Substrates of Eating and Alcohol Use Disorders
A substantial percentage of individuals with bulimia nervosa (BN) also meet criteria for a co-occurring substance use disorder, such as alcohol abuse or dependence; however, research examining this sub-group of patients with BN…
- Trial name
- NCT01172210
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Alcohol Use Disorder
Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
Twenty participants, age 18 or older, who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for moderate to severe Alcohol Use Disorder will be randomized to open-label psilocybin (25 mg) therapy with…
- Trial name
- NCT04410913
- Testing
- Psilocybin plus Visual Healing Set and Setting, Psilocybin plus Standard Set and Setting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Keith Heinzerling
Chronic Hepatitis, Chronic Hepatitis C
The Effect of High Dose Vitamin C on the Liver Function in Chronic Hepatitis Patients
The investigators will evaluate the efficacy of high dose vitamin C in chronic hepatitis patients whose serum liver enzymes are elevated more than upper limit.
- Conditions
- Chronic Hepatitis, Chronic Hepatitis C, Chronic Alcoholic Hepatitis
- Trial name
- NCT01413360
- Testing
- High dose vitamin C
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Substance Use Disorders, Opiate Dependence
The Effect of Self-Forgiveness on Self-Stigma in Addiction.
This study has an experimental design and will examine the difference in pre-test and post-test data on the Self-Forgiveness Dual Process Scale (SFDPS) (Griffin, Worthington, Davis, Hook, \& Maguen, 2018) and the Substance Abuse…
- Conditions
- Substance Use Disorders, Opiate Dependence, Opiate Withdrawal Syndrome, Opioid-use Disorder
- Trial name
- NCT03971097
- Testing
- Six Step Model of Self-Forgiveness, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Pittsburgh
Alcohol-dependence
The Effects of Treatment With Naltrexone in Alcohol and Cannabis-dependent Patients
Alcohol dependence is a major health problem worldwide and recently in Israel and it has major health care costs. Cannabis dependence is also a major health issue and many cannabis users find it difficult to quit.
- Trial name
- NCT01560013
- Testing
- Naltrexone
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Drug Dependence, Alcohol Dependence
Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits
Addiction to illicit and prescribed drugs, alcohol and tobacco is associated with a panoply of brain changes that contribute to structural and micro-structural deficits, altered metabolism and neurotransmission, and related…
- Trial name
- NCT01171677
- Testing
- IntenSati
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Alcohol Use Disorder, Deep Brain Stimulation
Efficacy and Safety of Dual-target Deep Brain Stimulation for Treatment-resistant Alcohol Use Disorder
This is a multi-center, single arm, prospective, open-label, extendable study for the efficacy and safety of dual-target deep brain stimulation for treatment-resistant alcohol use disorder.
- Trial name
- NCT05884619
- Testing
- Dual-target deep brain stimulation
- Where
- 4 sites in China
- Volunteers
- 12 people
- Sponsor
- Second Xiangya Hospital of Central South University
Alcohol Use Disorder (AUD)
Mobile Rewarding Activity Centered Treatment
Alcohol Use Disorder (AUD) is a highly prevalent and significant public health problem. Behavioral treatments based in the principles of social learning theory and cognitive behavior therapy have been developed and tested for…
- Trial name
- mReACT (NCT05064228)
- Testing
- Mobile Rewarding Activity Centered Treatment (m-ReACT)
- Volunteers
- 50 people
- Sponsor
- University of Central Florida
Alcohol-Related Disorders, Alcohol Use Disorders
Component Analysis for Motivational Interviewing
The purpose of this study is to investigate the critical components of motivational interviewing (MI), a psychotherapeutic intervention, in reducing heavy or problematic drinking.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT01642381
- Testing
- Full Motivational Interviewing ("FMI"), Spirit Only Motivational Interviewing ("SOMI")
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Northwell Health
Stress Disorders, Post-Traumatic, Substance Use Disorders
Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment
Many people who have posttraumatic stress disorder (PTSD) also struggle with problematic alcohol or drug use (substance use disorders [SUD]). Patients with both conditions prefer PTSD be treated alongside SUD.
- Trial name
- COMPASS (NCT04581434)
- Testing
- Prolonged Exposure Therapy, Cognitive Processing Therapy, Present Centered Therapy
- Where
- 14 sites in United States
- Volunteers
- 426 people
- Sponsor
- Center for Veterans Research and Education
BHB Transport, Alcohol Use Disorder
Metabolism in the Human Brain Following Consumption of a Keto-ester in Alcohol Use Disorder (AUD) With Proton Magnetic Resonance Spectroscopic Imaging (MRSI)
The objective of this study is to determine whether BHB levels in the brain will be positively associated with alcohol consumption, due to hypothesized enhancement of BHB transport into the brain.
- Trial name
- NCT05937893
- Testing
- Keto-ester followed by Magnetic Resonance Spectroscopic Imaging (MRSI) scans
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Brief Family Involved Treatment Telehealth
Improving alcohol use disorder (AUD) treatment among Veterans is a national public health problem. The rate of AUD among Veterans is twice that of civilians, with up to 50% of Veterans having AUD.
- Trial name
- B-FIT (NCT05674409)
- Testing
- Brief Family-Involved Treatment (B-FIT), Cognitive Behavioral Therapy for Alcohol Use Disorder (CBT for AUD)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Medical University of South Carolina
Alcoholic Liver Disease, Chronic Hepatitis C Virus Infection
sgp130 in Chronic Human Liver Disease
Chronic liver disease are characterized by increased levels of plasma IL-6, but the bioactivity of this cytokine in this disease is not well known.
- Trial name
- NCT00770198
- Where
- Belgium
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
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