Clinical trials: Alcohol-induced Disorders
Pancreatitis, Acute, Helicobacter Infections
Helicobacter Pylori and Acute Alcohol Induced Pancreatitis
This study is performed to measure wether Helicobacter Pylori has an effect on the incidence and course of acute alcohol induced pancreatitis
- Trial name
- NCT00490386
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Tampere University
Alcohol Use Disorder
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
This study aims to determine the safety and preliminary efficacy of psilocybin-assisted psychotherapy in improving alcohol-related outcomes among adults with severe alcohol use disorder in a a double-blind, dose-comparison…
- Trial name
- NCT07296094
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Brigham and Women's Hospital
Alcohol Use Disorder, Trauma, Psychological
Adverse Childhood Experiences in Substance-related Disorders
Aversive childhood experiences (ACE) and their relation to the development of an alcohol use disorder will be measured with fMRI.
- Trial name
- NCT03758053
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Alcohol Dependence
A Study of Brain Receptor Occupancy in Healthy Subjects
To measure the occupancy of brain kappa opioid receptors after single oral doses of LY2456302.
- Trial name
- NCT01232439
- Testing
- opioid receptor kappa antagonist
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Alcohol Dependence
The Approach and Avoidance Task (AAT) in Alcoholic Inpatients
The approach and avoidance task (AAT) has evolved as a promising treatment add-on in the realm of psychology. Certain psychiatric diseases, such as behavioural addictions, social anxiety disorder, and arachnophobia, are…
- Trial name
- NCT04054336
- Testing
- Inhibit AAT, classical AAT, Control Group
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Substance Use (Drugs, Alcohol)
Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention
The purpose of this research study is to learn if an emergency department screening and telehealth intervention reduces substance use among individuals receiving emergency department treatment at The Ohio State University Wexner…
- Trial name
- ED-SMART (NCT07527871)
- Testing
- ED-SMART intervention, Substance use information
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Purdue University
Alcohol Use Disorder (AUD)
Evaluation of a Virtual Reality-based Version of the Multiple Errands Test in Alcohol Use Disorder
The goal of this study is to validate the virtual version of the Multiple Errands Test (V-MET) as a tool for assessing executive functions in patients with alcohol use disorder (AUD). More specifically, the project aims to: 1.
- Trial name
- EVIMETAL (NCT07593664)
- Testing
- Multiple Errand Test (MET), Virtual MET
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome
Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders
The purpose of this study is to determine whether choline supplementation can improve cognitive functioning of children with prenatal alcohol exposure.
- Conditions
- Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol-related Neurodevelopmental Disorder
- Trial name
- NCT01911299
- Testing
- Choline
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- San Diego State University
Substance Use Disorders, Alcohol Abuse
Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment
The Contracts, Prompts, and Social Reinforcement (CPR) intervention was designed to address the continuing care adherence needs of veterans presenting for substance use disorder (SUD) treatment.
- Conditions
- Substance Use Disorders, Alcohol Abuse, Alcoholism, Substance Dependence
- Trial name
- NCT00288886
- Testing
- Contracting, Prompting and Reinforcement arm, Control arm
- Where
- 2 sites in United States
- Volunteers
- 183 people
- Sponsor
- US Department of Veterans Affairs
Alcohol Use Disorder, Alcohol Drinking
Pitolisant Effects on Alcohol Self-Administration in Heavy Drinkers
This is a double-blind, randomized, placebo-controlled, crossover design trial that will test the effect of pitolisant on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT04596267
- Testing
- Pitolisant
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Medical Center
Alcohol Use Disorder
Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 2
Directly reinforcing abstinence from alcohol with monetary incentives is an effective treatment for alcohol dependence, but barriers in obtaining frequent, verified biochemical measures of abstinence limit the dissemination of…
- Trial name
- NCT03942770
- Testing
- Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Mikhail N Koffarnus
Alcohol Dependence, Cocaine Dependence
Combined Treatment for Cocaine-Alcohol Dependence - 1
The purpose of this study is to examine whether Naltrexone and cognitive behavioral therapy can be helpful in patients who want to stop using cocaine and alcohol.
- Trial name
- NCT00218569
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Alcohol Dependence
Effectiveness of Naltrexone and/or Ondansetron to Reduce Craving for Alcohol and Drinking
The purpose of this study is to determine whether naltrexone (an opiate blocking agent approved for the treatment of alcohol dependence), ondansetron a serotonin 3 antagonist medication approved to treat nausea) or their…
- Trial name
- NCT00183222
- Testing
- naltrexone (up to 50 mg/day) for 8 days; ondansetron (0.25 mg twice a day) for 8 days
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Addiction
Tdcs And cogNitive traininG cOmbined for AUD (TANGO)
The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches using transcranial direct…
- Trial name
- NCT05062369
- Testing
- TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Alcoholism
Prospective Assessment of Adolescent Drinking Trajectories With Computer-Assisted Self-administration of Ethanol (CASE)
The Computer-Assisted Self-administration of Ethanol (CASE)will be administered twice, at the ages 18 and 20, in a prospective study of 80 adolescents living in the Dresden area.
- Trial name
- NCT01063166
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alcohol Consumption, Alcohol Intoxication
A Text Message Behavioral Intervention to Reduce Alcohol Consumption in Young Adults
Investigators aim to test the effectiveness of a text-message-based behaivoral intervention in reducing binge drinking among young adults.
- Trial name
- TRAC (NCT01688245)
- Testing
- SMS Assessments & Feedback, SMS Assessments
- Where
- United States
- Volunteers
- 765 people
- Sponsor
- University of Pittsburgh
Tobacco Use Disorder, Alcohol Use Disorder
Cytisine for Smoking Cessation
The goal of this clinical trial is to evaluate the safety and effectiveness of cytisine as a smoking cessation treatment in individuals with concurrent alcohol use disorder.
- Conditions
- Tobacco Use Disorder, Alcohol Use Disorder, Smoking Cessation
- Trial name
- NCT05729243
- Testing
- Cytisine
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking, Tobacco Dependence
Varenicline Treatment for Active Alcoholic Smokers
Alcohol dependence is a significant and prevalent public health problem affecting approximately 4% of the U.S. adult population.
- Conditions
- Smoking, Tobacco Dependence, Alcohol Dependence
- Trial name
- NCT01347112
- Testing
- Varenicline
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alcohol-Related Disorders, Depressive Disorder
Psilocybin in Alcohol Use Disorder With Comorbid Depression
Up to 40% of people with alcohol use disorder (AUD) experience depression. Depression is a risk factor for early relapse of AUD after withdrawal in a controlled environment.
- Conditions
- Alcohol-Related Disorders, Depressive Disorder, Addiction
- Trial name
- PAD (NCT06235411)
- Testing
- Psilocybin therapy, Inactive Psilocybin therapy, Electroencephalogram
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Alcohol Use Disorder, Alcohol-associated Liver Disease
Implementation Facilitation Pilot for Alcohol Use Disorder (AUD) in Alcohol-associated Liver Disease (ALD)
The goal of this project is to improve provision of integrated medications for alcohol use disorder (MAUD) with brief counseling for patients with alcohol use disorder (AUD) and alcohol-associated liver disease (ALD) in…
- Trial name
- NCT07525258
- Testing
- Implementation Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yale University
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