Clinical trials: Alcohol-induced Disorders
Alcohol Withdrawal, Alcohol Abstinence
Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients
Alcohol withdrawal syndrome is a highly morbid condition affecting a substantial percentage of patients hospitalized who have alcohol use disorders, estimated at 5-6% of all hospitalized patients.
- Conditions
- Alcohol Withdrawal, Alcohol Abstinence, Alcohol Use Disorder
- Trial name
- NCT07810946
- Testing
- Sodium Acetate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder
CBT4CBT With Spanish Alcohol Users
Specific aims are as follows: To adapt our existing CBT4CBT program for use with Spanish-speaking alcohol users in a web-based platform To conduct an 8-week randomized trial evaluating the feasibility and efficacy of adding…
- Trial name
- NCT03474588
- Testing
- Standard treatment (ST) PLUS web-based CBT4CBT, Standard Treatment (ST)
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- Yale University
Chronic Pain
Managing Chronic Pain in Veterans With Substance Use Disorders
The proposed project will provide crucial data on the effectiveness of a pain management intervention designed for veterans with co-occurring pain and substance use disorders.
- Trial name
- NCT00982410
- Testing
- cognitive-behavioral treatment, educational supportive group
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- US Department of Veterans Affairs
Alcohol Withdrawal Delirium
Treatment Of Alcohol Withdrawal Syndrome: Dexmedetomidine Vs Diazepam In A Hospital O'horán
The cessation of alcohol consumption of people suffering from alcohol abuse frequently leads to the development of an alcohol withdrawal syndrome (AWS).
- Trial name
- NCT03877120
- Testing
- Dexmedetomidine 0.004 MG/ML, Diazepam Injectable Solution
- Where
- Mexico
- Volunteers
- 2 people
- Sponsor
- Centro Medico Nacional La Raza, IMSS
Infection, Alcohol Abuse
Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure
This study plans to learn more about people who are sick in the hospital with a lung infection, or respiratory failure. Respiratory failure, or severe lung failure, is a life-threatening disease.
- Conditions
- Infection, Alcohol Abuse, Drugs of Abuse, Lung Injury
- Trial name
- NCT02299921
- Testing
- Characterize alcohol and drug use
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Substance-related Disorders, Alcohol-related Disorders
Specialized Substance Abuse Supervision (SSAS) Versus Non-SSAS Recidivism Rates Among Nebraska Felony Drug Offenders
This social science study hypothesizes that convicted felony drug offenders in Nebraska who participated in Specialized Substance Abuse Supervision (SSAS) as part of their probation or parole showed significantly better outcomes…
- Trial name
- SSAS (NCT00690352)
- Testing
- Specialized Substance Abuse Supervision (SSAS)
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Nebraska
Prostate Cancer, Urologic Cancer
The Man Van Project
National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care…
- Conditions
- Prostate Cancer, Urologic Cancer, Urologic Diseases, Bladder Cancer
- Trial name
- MV (NCT06357416)
- Testing
- MV-POCT Sub-study, Main Man Van Group Sub-study (MV-Eco), MV-QualQ Sub-study
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Alcohol Abuse With Alcohol-Induced Sleep Disorder, Alcohol Use Disorder (AUD)
Smartphone-Based Intervention for Sleep Disturbance in Individuals Recovering From Alcohol Use Disorder
In order to assess the efficacy of the rhythm stabilization component of Health Rhythms' product in addressing sleep problems, investigators will recruit 128 outpatients over the age of 18, who are in early recovery (at least 2…
- Conditions
- Alcohol Abuse With Alcohol-Induced Sleep Disorder, Alcohol Use Disorder (AUD), Sleep Disorder, Sleep Disturbance
- Trial name
- NCT06108115
- Testing
- CueToSleep (Full Intervention Package)
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- HealthRhythms, Inc.
Alcoholism
Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support
Hazardous drinking is common among Veteran primary care patients and increases risk for more costly and complex medical problems over the long-term. Yet, the vast majority of these Veterans go untreated.
- Trial name
- PS-Stand Down (NCT05473598)
- Testing
- Stand Down app, Peer-Supported Stand Down, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 234 people
- Sponsor
- VA Office of Research and Development
Alcoholism
Study To Examine Effect Of CP-866,087 On Consumption And Craving Of Alcohol In Alcohol Dependent Subjects.
Test the hypothesis that increasing doses of CP-866,087 will decrease the total number of drinks consumed during a 2 hour acute alcohol consumption assessment and to determine the safety and tolerability of multiple doses of…
- Trial name
- NCT00147576
- Testing
- CP-866,087
- Where
- 11 sites in United States
- Volunteers
- 88 people
- Sponsor
- Pfizer
Alcohol Dependence
Fish Oil vs. Placebo on Subjective Effects of Alcohol
This project represents a first step in examining the potential use of fish oil for the treatment of alcohol use disorder (AUD).
- Trial name
- NCT03010917
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV, Substance Use (Drugs, Alcohol)
VR Mindfulness for People With HIV and Substance Use
The goal of this clinical trial is to explore whether a virtual reality (VR) mindfulness app is acceptable, appropriate, and feasible for supporting people with HIV and substance use problems.
- Trial name
- NCT07088289
- Testing
- TRIPP
- Volunteers
- 30 people
- Sponsor
- Tulane University
Teen Drinking
Online Education Hubs and Chat-based Text Messaging for Reducing Alcohol Consumption and Binge Drinking in Adolescents: A Pilot Randomized Controlled Trial
Online education hubs and Chat-based text messaging for reducing alcohol consumption and binge drinking in adolescents: A pilot randomized controlled trial
- Trial name
- NCT07143565
- Testing
- Online platform hub and mHealth Text Messaging, Self-help material
- Where
- 2 sites in Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Alcohol Addiction
Repetitive Transcranial Magnetic Stimulation (rTMS) of the Insula for Treatment of Alcohol Addiction
The purpose of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) targeting the insula on alcohol use and neural responses in alcohol-dependent patients.
- Trial name
- NCT02643264
- Testing
- rTMS 10 Hz targeting the insula
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Linkoeping University
Alcohol Drinking Related Problems, Alcohol Use Disorders
Co-occurence of Mental Illness and Problematic Alcohol Use: an Internet-based Cognitive Behavior Therapy Intervention
The goal of this clinical trial is to learn if internet-based cognitive behavior therapy (ICBT ) works to treat co-occurent of problematic alcohol use and mental illness including mild to moderate symptoms of either depression…
- Conditions
- Alcohol Drinking Related Problems, Alcohol Use Disorders, Depressive Disorders, Mental Illness
- Trial name
- CoMiT (NCT06789250)
- Testing
- Internet-based cognitive behavior therapy
- Where
- 2 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Linkoeping University
Alcohol Use Disorder
Training Inhibition in Alcohol Use Disorder
More and more studies aim to improve neurocognitive functioning in alcohol use disorder, but very few studies have focused on training-inhibitory-control efficacy on alcohol intake.
- Trial name
- TRAIN (NCT03530384)
- Testing
- Cognitive training, Control training
- Where
- France
- Volunteers
- 227 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Suicide, Alcohol Use Disorder
Facilitating Use of the National Suicide Prevention Lifeline in Alcohol Patients (Reach Out)
The purpose of this research study is to learn about people who use the National Suicide Prevention (NSP) Lifeline during a suicidal crisis and those who don't.
- Trial name
- NCT04488055
- Testing
- Crisis Line Facilitation (CLF), Enhanced Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 530 people
- Sponsor
- University of Michigan
Cannabis, Cannabis Use
Marijuana Effects on Simulated Driving Performance
This study will examine the effects of various strains of marijuana on simulated driving performance; the effects of alcohol administration will also be examined to further understand how marijuana-induced driving changes compare…
- Conditions
- Cannabis, Cannabis Use, Marijuana, Marijuana Usage
- Trial name
- NCT03699540
- Testing
- Marijuana, Alcohol, Inactive marijuana
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shanna Babalonis, PhD
Cocaine Dependence, Alcohol Dependence
HBPL Study of the Impact of the NK1 Antagonist Aprepitant
The proposed research will focus on investigating the determinants and consequences of CAD via measurement of physiological, behavioral and subjective effects of physiologic and psychologic stress cues in CAD volunteers in the…
- Trial name
- NCT01176591
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pennsylvania
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