Clinical trials: Alcohol-induced Disorders
Intoxication Alcohol
Stop-Service to Obviously-Impaired Patrons
The Responsible Retailing Forum ("RRF") seeks to develop a new intervention, Stop Service to Obviously- Impaired Patrons ("S-STOP"), to reduce the incidence and harm associated with overservice of alcohol.
- Trial name
- SSTOP (NCT03608787)
- Testing
- S-STOP
- Where
- United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- RRF Field Services LLC
Amphetamine Addiction
Robot-Assisted Intelligent Rehabilitation Treatment for Methamphetamine Use Disorders.
The purpose of this research is to evaluate the efficacy and safety of Robot-assisted rehabilitation intelligent system as a virtual stand-alone treatment, delivered with minimal clinical monitoring compared with treatment as…
- Trial name
- NCT04531384
- Testing
- robot-assisted rehabilitation intelligent treatment, standard psychotherapy treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Use Disorder, Posttraumatic Stress Disorder (PTSD)
Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders
The purpose of this study is to evaluate whether the combination of prazosin and naltrexone will decrease alcohol cravings and drinking in individuals who have problems with alcohol and have used alcohol at risky levels compare…
- Trial name
- PaN (NCT02322047)
- Testing
- Prazosin, Naltrexone
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Alcoholism
Naltrexone for Early Problem Drinkers
Early problem drinkers are prevalent in the United States. Recent controlled trials have shown that brief interventions in the primary care setting can reduce drinking and alcohol-related problems in patients who lack evidence of…
- Trial name
- NCT00000455
- Testing
- naltrexone
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- UConn Health
Stress Disorders, Post-Traumatic, Intimate Partner Violence
Addressing the Health Concerns of VA Women With Sexual Trauma
Lifetime sexual trauma (ST) (i.e., behaviors that range from unwanted sexual touching to attempted or completed rape) is a significant social and public health problem among women Veterans.
- Conditions
- Stress Disorders, Post-Traumatic, Intimate Partner Violence, Alcohol-Related Disorders
- Trial name
- SHE (NCT02957747)
- Testing
- SHE
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VISN 17 Center of Excellence
Prenatal Alcohol Exposure, Fetal Alcohol Spectrum Disorders
Families Moving Forward Bridges: An Early Intervention for Infants and Toddlers With PAE With or At-risk for FASD
This is an unblinded, feasibility study of an adapted positive parenting intervention to be carried out in a small sample (n=12 dyads) of young children with FASD and their primary caregiver in King County, WA.
- Trial name
- NCT06935461
- Testing
- Families Moving Forward Bridges
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Alcohol Use Disorder (AUD)
Effectiveness of Nurse-Conducted Brief Intervention (NCBI) Supplemented With Mobile for Preventing Alcohol Use Disorders
The study is aimed to find out that combining Nurse-Conducted Brief Intervention (NCBI) with a Smart Mobile is better than Nurse-Conducted Brief Intervention (NCBI) only in preventing relapse among Alcohol Use Disorder patients.
- Trial name
- NCT06652802
- Testing
- Nurse-Conducted Brief Intervention (NCBI). supplemented with mobile based application., Nurse-Conducted Brief Intervention (NCBI)
- Volunteers
- 74 people
- Sponsor
- University of Pittsburgh
Alcohol Use Disorder, Alcoholism
Naltrexone in AUD Reward Drinkers
This study is a phase IV, two-arm, randomized, double-blind, placebo-controlled study to assess whether individuals identified as primarily reward drinkers are significantly more likely to reduce heavy drinking if they receive…
- Trial name
- NCT05028062
- Testing
- XR-NTX 380 mg, intramuscular injection, Medical Management
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Fetal Alcohol Spectrum Disorders
FASST - Fetal Alcohol Spectrum Stimulant Trial
This study is a double-blind, placebo controlled, series of N-of-1 trials of individualised stimulant dose on ADHD symptomatology in children with FASD.
- Trial name
- FASST (NCT04968522)
- Testing
- Methylphenidate Hydrochloride, Methylphenidate Hydrochloride 18 MG, Dexamphetamine sulfate
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Monash Medical Centre
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcoholic Liver Disease
Long Term Effect of Aggressive Nutritional Management on Survival in Patients With Alcoholic Liver Disease
Patient found to be malnourished after the nutritional evaluation would be randomized in the two groups of the study. The control group would receive standard nutritional counseling from a trained dietician where as those in the…
- Trial name
- NCT02140294
- Testing
- Polymeric nutritional supplements, Standard Nutrional Treatment
- Where
- India
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Alcohol Use Disorder
N-Acetylcysteine for Adolescent Alcohol Use Disorder
This is a 8-week randomized, placebo-controlled trial testing the effects of N-acetylcysteine (NAC), on a platform of weekly evidence-based brief alcohol intervention for 120 adolescents with alcohol use disorder (AUD).
- Trial name
- NCT03707951
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Medical University of South Carolina
Alcoholism
Simultaneous Measurement of Electroencephalography (EEG) and Functional Magnetic Resonance Imaging (fMRI) in Patients With Alcoholism
Investigation of inpatients with alcoholism after detoxification with simultaneous Electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI).
- Trial name
- NCT00216905
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Alcoholism, Alcohol Dependence
Behavioral Therapy Plus Naltrexone for Alcoholism
This study will compare cognitive behavioral therapy with a time-limited motivational enhancement therapy to which naltrexone (Revia) or placebo medication is added.
- Trial name
- NCT00000456
- Testing
- naltrexone (Revia), cognitive behavior therapy, motivational enhancement therapy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Medical University of South Carolina
Substance Use (Drugs, Alcohol), Substance Use Risk
Options for Navigating Talking About Risk and Adolescent Choices
This study will examine the effectiveness of ON-TRAC (Options for Navigating Talking about Risk and Adolescent Choices), which is an online substance use prevention program that also teaches emotion regulation skills.
- Conditions
- Substance Use (Drugs, Alcohol), Substance Use Risk, Substance Use, Emotion Regulation
- Trial name
- ON-TRAC (NCT06754527)
- Testing
- ON-TRAC
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
PTSD, Alcohol Abuse
Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy
The proposed project aims to: 1. Obtain a preliminary assessment of the efficacy of topiramate treatment in reducing alcohol use in veterans with Post Traumatic Stress Disorder (PTSD) and alcohol dependence; 2.
- Conditions
- PTSD, Alcohol Abuse, Alcoholism
- Trial name
- TAP (NCT01087736)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Alcohol Use Disorders
Development of Ibudilast for Alcohol Use Disorder
The objective of this proposal is to advance medication development for alcoholism by conducting a safety and initial efficacy study of ibudilast, a neuroimmune modulator and phosphodiesterase inhibitor, for alcohol use disorders.
- Trial name
- NCT02025998
- Testing
- Ibudilast
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Los Angeles
Alcohol Use Disorder
[C-11]PiB PET Imaging in Alcohol Use Disorders
To determine whether alcoholics (AUD) have a greater rate of amyloid positivity (ABeta+) compared to an age-matched cognitively normal control group (HC).
- Trial name
- NCT03746366
- Testing
- [C-11], Pittsburgh Compound B
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Use Disorder
Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders
At least 60% of Veterans with an alcohol use disorder will relapse within 6 months of treatment, irrespective of the type of treatment they receive.
- Trial name
- NCT03191266
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- VA Office of Research and Development
Substance Use (Drugs, Alcohol)
International Latino Research Partnership
Through a grant funded by the National Institute on Drug Abuse (NIDA) the Center for Multicultural Mental Health Research at Cambridge Health Alliance is testing a screening and intervention project designed to improve the…
- Trial name
- ILRP (NCT02038855)
- Testing
- Integrated Intervention for Dual Problems and Early Action
- Where
- 3 sites in United States, Spain
- Volunteers
- 360 people
- Sponsor
- Massachusetts General Hospital